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RI-INBRE > Bioinformatics Software Packages

Bioinformatics Software Packages

Sequencher

Sequencher is the premier choice for DNA sequence assembly and analysis. The program helps users go from sequence data to results quickly via an intuitively designed user interface. Features of Sequencher include:

  • Variance Table to find SNPs quickly
  • Reference Sequence for comparative alignment
  • Extensive Sequence Editing functions
  • Ability to import and edit GenBank Features
  • Support for Confidence Values
  • Reusable Project Templates for repetitive analyses
  • Updated mitotyping tools for forensics

DS Gene

DS Gene is a powerful desktop nucleic acid and protein sequence analysis package. The easy-to-use interface lets users quickly and easily perform many sequence analysis procedures. The program has the ability to access GCG databases with Blast and FastA.

The Wisconsin Package

The Wisconsin Package: a large, comprehensive sequence analysis package, which contains over 130 programs covering almost every aspect of sequence analysis. Based on published algorithms from the fields of mathematical and computational biology, the package includes:

  • Database Searching
  • Multiple Sequence Alignment and Analysis
  • Sequence Editing and Comparison
  • Fragment Assembly
  • Protein Analysis
  • Restriction and Proteolytic Enzyme Mapping
  • Evolutionary Analysis
  • DNA and RNA Folding
  • Pattern, Motif, and Gene Finding
  • Primer Prediction

There are two interfaces to the Wisconsin package:

SeqWeb: SeqWeb provides a simple web interface to a core set of sequence analysis programs in the GCG Wisconsin Package.

The following databases are available through SeqWeb:

  • PIR
  • SWISS-PROT
  • EMBL
  • NRL 3D
  • GenBank

Log onto SeqWeb

SeqLab: SeqLab provides access to sequence analysis applications in the Wisconsin package running on the SunBlade server. SeqLab provides access to 111 sequence analysis applications in the Wisconsin package running on the server. In addition to providing access to wide range of analysis tools in the Wisconsin package, SeqLab also offers a powerful, interactive sequence editor as well as convenient project management capabilities. SeqLab not only allows access to a wider range of applications from the Wisconsin package than SeqWeb, but also is more convenient for frequent users than SeqWeb.

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RI-INBRE Newsletter Winter 2013

Grant Workshop PowerPoint Presentations & Handouts

Balancing Teaching and Research at PUIs


Components of a Successful AREA (R15) Grant


NSF-RUI Program: Strategies and Tips for Success


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NIH Public Access Policy


NIH R15 Submission Deadlines - June 25, October 25, & February 25

3/22/2013 - "Revealing Nonobvious Features in Noncoding Human DNA - Insights for Evolution, Gene Expression and Disease" by Laura Elnitski, Ph.D., National Human Genome Institute, National Institutes of Health


8/14/2013-8/16/2013 - 5th Northeast Regional IDeA Meeting, University of Delaware, Newark, DE


4th Northeast Regional IDeA Meeting, Salve Regina University, Newport, RI


RI Inbre Research Fellows

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