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Faculty
Development Projects
Characterization of
Kinesin-3 and Kinesin-3 Cargo in Transit within the Axon (2009 - Present)
Investigator:
Joseph DeGiorgis,
Providence College
Mentor:
Thomas Reese, National Institute of Health
Abstract:
Axonal transport is a process in which membrane bound particles are in
transit along microtubules powered by motor proteins belonging to the kinesin and cytoplasmic dynein superfamilies.
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Student Training Projects
Genetic Characterization of UTH1 and BXI1, Two Genes Involved in Yeast
Programmed Cell Death (2009 - Present)
Investigator:
Nicanor Austriaco, Providence College Mentor: Brian Kennedy,
University of Washington School of Medicine
Abstract:
Apoptosis is both an important physiological process and
a significant anti-tumor defense mechanism in multicellular organisms.
Cells that bypass apoptosis in response to oncogenic stimuli can
undergo malignant transformation.
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Population Genetics
and Genome Evolution of Viruses in an Aquatic Environment (2009 -
Present)
Investigator:
Marcia
Marston, Roger Williams University
Mentor: David
Rand, Brown University
Abstract:
Bacteriophages are
important conduits for horizontal gene exchange among bacteria and
are directly responsible for the virulence of many bacterial
pathogens. Phage-encoded virulence factors include the shiga toxins
in pathogenic strains of Escherichia coli, the cholera toxin in
Vibrio cholerae, and the botulinum neurotoxins in Clostridium
botulinum.
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Investigating the Significance of Novel Forms of Ufd2a to Muscle
Differentiation (2009 -
Present)
Investigator:
Sarah
Spinette, Rhode Island College Mentor:
David Goldhamer, University of Connecticut
Abstract: The way in which
cells achieve their differentiation program is intimately tied to
changes in their proteome occurring via several mechanisms including,
transcription factor activation or inhibition of transcription events,
tissue specific regulation of splicing machinery resulting in
alternatively spliced transcripts, ubiquitin dependant proteosomal
degradation, and post-translational modification.
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Presentations |
Students Trained |
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Honors & Awards |
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