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Elucidation of Biochemical Pathways in the Striatum Involved in Controlling Movement and Drug-Addiction
The striatum is a region of the brain that is involved in controlling movement.  The striatum is also activated by stimuli associated with reward and thus is important drug addiction.  Our lab studies a protein, RGS9-2, that is specifically expressed in the striatum and has been shown to modulate striatal dopamindergic and opioid pathways.  These pathways have been shown to be important in the striatal control of movement and drug addiction, and experiments using mice in which the RGS9 gene has been knocked out have confirmed an important role for RGS9-2 in these processes.  For this project we will study how RGS9-2 modulates the expression and trafficking of dopamine and opioid receptors expressed in striatal neurons so as to better understand the biochemistry of movement and drug-addiction.
 News & Events

RI-INBRE Newsletter Fall 2009

RI-INBRE Newsletter Fall 2009

Grant Workshop PowerPoint Presentations & Handouts

Balancing Teaching and Research at PUIs

Components of a Successful AREA (R15) Grant

NSF-RUI Program: Strategies and Tips for Success

Handouts

Important Dates

RI-INBRE Calendar

12/3//09 - Shahram Khademi, Ph.D, University of Iowa - "The structure and mechanism of ammonia channels"

12/4/09 - 4th Annual BioNES Meeting, Roger Williams University, Bristol, RI

1/29/10 - RI-INBRE Research Fellows Meeting & Faculty Retreat, Providence College, Providence, RI

3/1/10 - Application Deadline for the 2010 Summer Undergraduate Research Fellowships

6/16/10 - 6/18/10 National IDeA Symposium of Biomedical Research Excellence, Bethesda, MD

 Supported by grant #  P20RR016457 from:
Contact Info
Contact RI INBRE:  
University of Rhode Island
Fogarty Hall		 | 41 Lower College Rd | Kingston, RI 02881
Phone: (401) 874-9288 | Fax: (401) 874-2646 | E-mail: riinbre@etal.uri.edu