Molecular and
nutritional basis for E. coli colonization of the intestine
Current projects
involve investigating the molecular and nutritional factors that
comtribute to the ability of commensal and pathogenic strains of E. coli
to colonizine the intestinal tract. The project makes use of a mouse
model, involves the construction of mutatant strains of E. coli with
altered colonizing ability, and investigation of the underlying molecular
and regulatory mechanisms that enhance of diminish colonizing ability.
