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Development of Multifunctional Anti-HIV and Anti-Cancer Agents
The purpose of this project is to develop multifunctional anti-HIV or anticancer agents by covalently conjugating several biologically active compounds. The hypothesis underlying this proposal is that safe, potent, and broad-spectrum multifunctional anti-HIV or anti-cancer agents can be designed to deliver and release different active compounds intracellularly at the same time. Furthermore, development of resistance to several active drugs would occur at a much slower rate than to either compound alone. The attachment of fatty acids in some analogs will enhance the lipophilicity and thus the cellular uptake of these multifunctional conjugates.
 News & Events

RI-INBRE Newsletter Fall 2009

RI-INBRE Newsletter Fall 2009

Grant Workshop PowerPoint Presentations & Handouts

Balancing Teaching and Research at PUIs

Components of a Successful AREA (R15) Grant

NSF-RUI Program: Strategies and Tips for Success

Handouts

Important Dates

RI-INBRE Calendar

12/3//09 - Shahram Khademi, Ph.D, University of Iowa - "The structure and mechanism of ammonia channels"

12/4/09 - 4th Annual BioNES Meeting, Roger Williams University, Bristol, RI

1/29/10 - RI-INBRE Research Fellows Meeting & Faculty Retreat, Providence College, Providence, RI

3/1/10 - Application Deadline for the 2010 Summer Undergraduate Research Fellowships

6/16/10 - 6/18/10 National IDeA Symposium of Biomedical Research Excellence, Bethesda, MD

 Supported by grant #  P20RR016457 from:
Contact Info
Contact RI INBRE:  
University of Rhode Island
Fogarty Hall		 | 41 Lower College Rd | Kingston, RI 02881
Phone: (401) 874-9288 | Fax: (401) 874-2646 | E-mail: riinbre@etal.uri.edu