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Faculty Publications
Compiled by Margaret J. Keefe

Faculty Publications 2010

Biomedical & Pharmaceutical Sciences

Abdelrahim, M., S. KoduriI, M. R. Basha, P. A. Philip and C.H. Baker.  "Angiogenesis: An Update and Potential Drug Approaches." International Journal of Oncology. 36(1):5-18. January 2010.

Abernathy, Amy P., Noreen M. Aziz, Ethan Basch, Janet Bull, Charles S. Cleeland, David C. Curow, Diane Fairclough, Laura Hanson, Joshua Hauser, Danielle Ko, Linda Lloyd, R. Sean Morrison, Shirley Otis-Green, Steve Pantilat, Russell K. Portnoy, Christine Ritchie, Graeme Rocker, Jane L. Wheeler, S. Yousef Zafar and jean S. Kutner. "A Strategy to Advance the Evidence Base in Palliative Medicine: Formation of a Palliative Care Research Cooperative Group." Journal of Palliative Medicine. 13(12):1407-1413. December 2010.

Adams, Lynn S., Sheryl Phung, Natalie Yee, Navindra P. Seeram, Liya Li and Shiuan Chen. "Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells Through Modulation of the Phosphatidylinositol 3-Kinase Pathway." Cancer Research. 70(9):3594-3605. May 1,  2010.

Agarwal, Hitesh K., Anial Kumar, G. F. Doncel and Keykavous Parang. "Synthesis, Antiviral and Contraceptive Activities of Nucleoside-Sodium Cellulaose Sulfate Acetate and Succinale Conjugates." Bioorganic & Medicinal Chemistry Letters. 20(23):6993-6997. December 1, 2010.

Ahmadibeni, Yousef, Chandravnu Dash, Stuart F. J. Le Grice and Keykavous Parang. "Solid-Phase Synthesis of 5'-O-beta-O, Beta-methylenetriphosphate Derivatives of Nucleosides and Evaluation of Their Inhibitory Activity Against HIV-1 Reversed Transcriptase." Tetrahedron Letters. 51(22):3010-3013. June 2010.

Ahmadibeni, Yousef, Rakesh Tiwari, Gustavo F. Doncel and Keykavous Parang. "Synthesis of Bis(cycloSaligenyl) Pronucleotides Containing Two Nucelosides From Bis(Methoxy....Benzone-1,4-diol (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  ORG-1075.

Ahmadibeni, Yousef and Keykavous Parang. "Synthesis of Branded Triphosphatye Triester Conjugates of Anti-HIV Nucleosides  (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  ORGN-1075.

Ahmadibeni, Yousef, Benjamin Carroll, Gustavo F. Doncel and Keykavous Parang. "Synthesis of Lipophite Dodecyl bis(acyleSaligenyl) Nucleoside Monophosphate Triesters  (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  ORGN-1019.

Ahmadibeni, Y., C. Dash, M. J. Hanley, S. F. J. Le Grice, H. K. Agarwal and K. Parang. "Synthesis of Nucleoside 5'-O-alpha, Beta-methylene-Beta-triphosphates and Evaluation of Their Potency Towards Inhibition of HIV-1 Reverse Transcriptase." Organic and Biomolecular Chemistry. 8:1271-1274. March 21, 2010.

Aiello, Robert J., Bret D. Perry, Patricia-Ann Bouressa, Andrew Robertson, Weifan Weng, Delvin R. Knight, Andrew H. Smith, Kosea S. Frederick, Amit Kalgutkar and Ronald P. Glague. "CCR2 Receptor Blockade Alters Blood Monocyte Subpopulationms But Does Not Affect Atherosclerotic Llesions in apoE/Mice." Atheroschlerosis. 208(2):370-375. February 2010.

Aklaghi, Fatemeh.  SEE also: Dostalek, Miroslav; Hu, Susie; Ionita, A.; Narwal, Rajesh; Pabla, Dimple.

Akhlaghi, F. and R. Y. Gohh. "The Level of ATP Production in Nitrogen-Stimulated CD4+ Lymphocytes Is Independent of the Time of Ingestion of Immunosuppresive Agents." Therapeutic Drug Monitoring. 32(1):116-117. 2010.

Akhlaghi, F., S. D. Chitnis, A. E. Mendoza, I. A. Ionita and R. Y. Gohn. "Reduced Level of Biomarkers of Immunosuppressive Activity in Diabetes Kidney Transplant Recipients Is Related Diabetes Type and Glucose Control (Abstract)." Clinical Pharmacology & Therapeutics. 87(Suppl.1):488. February 2010.

Asharobi, Omatola, Liya Li, David Worthen and Navindra Seeram. "Constituents of Maple Syrup Residue, a Waste/Byproduct of the Maple Syrup Industry (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010. AGFD-168.

Atkinson, Thomas M., Tito R. Mendoza, Laura Sit, Steven Passik, Howard I. Scher, Charles Cleeland and Ethan Basch. "The Brief Pain Inventory and Its "Pain at its Worst in the Last 24 Hours" Item: Clinical Trial Endpoint Considerations." Pain Medicine. 11(3):337-346. March 2010.

Aziz, Nazneen, Ashish K. Jha, Chris Thanos, Riyaz Basha and Arijit Bose. "Structural Markers in Prostate Cancer Serum Imaged ex Vivo Using Cryagenic Transmission  Electron Microscopy." Journal of Electron Microscopy. 59(5):451-456. October 2010.

Basch, Ethan M.  SEE also: Abernathy, Amy P.; Atkinson, Thomas M.; Gilligan, Timothy D.;  Jang, Thomas L.; Mularksi, Richard A.; Vickers, Andrew J.; Wang, X. S.

Basch, Ethan. "The Missing Voice of Patients in Drug-Safety Reporting." New England Journal of Medicine. 362(10):865-869. March 11, 2010.

Basch, E. M., L. SIt, M. Fruscione, L. Burke, R. Kane, D. George, M. A. Carducci, P. Matthew, T. M. Beer and H. I. Scher. "Pain and Analgesic Use in Men With Metastic Prostate Cancer (Abstract)." Journal of Clinical Oncology. 27(15,Suppl.S):e2055. May 20, 2010,

Basha, Mahammad Riyaz.  SEE: Abdelrahim, M.; Aziz, Nazneen; Jutooru, I.

Birmingham, Bruce K.  SEE: Wang, Y.

Blystone, Chad R., Grace E. Kissing, Jack B. Bishop, Robert E. Chapin, Gary W. Wolfe and Paul M. D. Foster. "Determination of the Di(2-Ethylhexyl)Phthalate NOAE for Reproductive Development in the Rat: Importance of the Retention of Extra Animals to Adulthood." Toxicological Sciences. 116(2):640-646. August 2010.

Boekelheide, Kim.  SEE also: Campion, Sarah N.; Krewski, Daniel.; Mehta, A.; Pacheco, S.; Yamasaki, Hideki.

Boekelheide, Kim and Eric M. Suuberg. Environmental Health and Chemical Exposures: Law & Science. Rhode Island bar Association. 2010.  70p.

Boekelheide, Kim and Sarah N. Campion. "Toxicity Testing in the 21st Century: Using the New Toxicity Testing Paradigm to Create a Taxonomy of Adverse Effects." Toxicological Sciences. 114(1):20-24. March 2010.

Bolser, Jessica, Liya Li,  Scott McWilliams and Navindra P. Seeram. "Polyphenal and Antioxidant Contents of Fruits Consumed by Migratory Birds in Southern New England (Abstract)." Abstracts of Papers of the American Chemical Society. 2010.  AGFD-237. March 21-25.

Bowman, Christopher J., Randal D. Streck and Robert E. Chapin. "Maternal-Placenta Insulin-Like Growth Factor (1GF_ Signaling and Its Importance to Normal Embryo-Fetal Development." Birth Defects Research. Pt. B - Developmental and Reproductive Toxicology. 89(4):339-349. August 2010.

Campbell, Norm. "Letter to the Editor." Mercury. September 2010.  p.32.

Campion, Sarah N., E. Andres Houseman, Moses A. Sandrof, Janan B. Hensley, Yunxia Sui, Kevin W. Gaido, Zhijin Wu and Kim Boekelheide. "Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. II.  Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways." Toxicological Sciences. 117(2):457-465. October 2010.

Campion, Sarah N., Moses A. Sandoro, Hideki Yamasaki and Kim Boekelheide. "Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. III. Candidate Gene Analysis Identifies a Role for Fas in the Attenuation of X-Ray-Induced Apoptosis." Toxicological Sciences. 117(2):466-474. October 2010.

Celver, Jeremy P.  SEE also: Masuho, Ikuo; Sharma, Meenakshi.

Celver, J., M. Sharma and A. Kovoor. "RGS9-2 Mediates Specific Inhibition of Agonist-Induced Internatlization of D1-Dopamine Receptors." Journal of Nerurochemistry. 114(3):739-749. August 2010.

Celver, Jeremy P., Janet Lowe, Abraham Kovoor, Vsevolod V. Gurevich and Charles Chaukin. "Threonine 180 Is Required for G-Protein-Coupled Receptor Kinase 3- and b-arrestin 2-Mediated Desensitatization of the m-Opioid Receptor in Xenopus Ooeytes." Journal of Biological Chemistry. 285(7):4894-4900. 12 February  2010.

Chapin, Robert E.  SEE: Blystone, Chad R.; Bowman, Christopher J.

Chhikara, Bhupender S. and Keykavos Parang. "Development of Cytarabine Prodrugs and Delvery Systems for Leukemia Treatment." Expert Opinion on  Drug Delivery. 7(12):1399-1421. December 2010.

Chhikara, Bhupender S., Deendayal Mandel and Keykavos Parang. "Synthesis and Anticancer Activity of Fatty Acid Derivatives of Cytarabine (Abstract)." Abstracts of Papers of the American Chemical Society. 2010.  MEMDI-49.

Chhikara, Bhupender S., Deendayal Mandel and Keykavos Parang. "Synthesis and Evolution of Fatty Acyl Ester Derivatives of Cytarabine as Anti-Leukemia Agents." European Journal of Medicinal Chemistry. 45(10):4601-4608. October 2010.

Chichester, Clinton O., III.  SEE: MacDonnell, Celia P.; Vincent, James; Wang, Qinghua.

Cho, Bongsup.  SEE also: Jain, Vipin; Liang, Fengting; Meneni, Srinivasarao; Patniak, Satyakam; Vaidyanathan, V. G.

Cho, Bongsup, Yue Zou, Marina Roginskaya and Benjamin A. Hilton. "Nucleotide Excision Repair of Cluster Bulky DNA Lesions (Abstract)." Clinical Research in Toxicology. 23(1) 283. January 2010.

Cho, Bongsup and Satyakam Patnaik. "Spectroscopic and Thermodynamic Insights Into Sequence Effects of 2-Acetlaminofluorene-Induced Conformational Heterogeneity  (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  TOXI-114.

Cho, Bongsup and Vaidnathan Ganson. "Role of Carcinogen-Induced Conform Meter in Translesion Synthesis (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  TOXI-113.

Cho, Bongsup. "Structure-Function Characteristics of Aromatic Amine-DNA Adducts."  IN: Chemical Biology of Brain Damage, Edited by Suse Borda and Nicholas Geancintov.  2010.  p.217-238.

Cierello, Amanda, Liya Li, Luke R. Howard and Navindra Seeram. "Phytochemicals in Blueberry (Vacinium corymboson) Stems  (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  AGFD-149.

Coles, Jeffrey. M., Jason J. Blum, Gregory D. Jay, Eric M. Darling, Farshid Guilqak and Stefan Zauchscher. "Corrigendum to 'In Situ Friction Measurement on Murine Cartilage by Atomic Force Microscope (Vol.41(3)(2008)541-548)'." Journal of Biomechanics. 43(14):2866. October 18, 2010.

Coles, Jeffrey M., Ling Zhang, Jason J. Blum, Matthew L. Warman, Gregory D. Jay, Farshid Guilak and Stefan Zauscher. "Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4." Arthritis and Rheumatism. 62(6):166-1674. June 2010.

Crooks, Peter A., Aimee K. Bence and David R. Worthen. Agmatine and Agmatine Analogs in the Treatment of Epilepsy, Seizure and Electroconvulsive Disorders. UR Patent 7,816,407. 2010.

Dedhiya, Mahendra.  SEE: Karakatsani, Marianthu.

Deng, Ruitang and Te-Jin Chow. "Hypolipidemic, Antioxidant, and IAntiiflammatory Activities of Microalgae Spirulina." Cardiovascular Therapeutics. 28(4):e33-e45. August 2010.

Dostalek, Miroslav, Joycer S. Macwan, Shripad D. Chitnis, Ileana A. Ionita and Fatemah Aklaghi. "Development and Validation of a Rapid and Sensitive Assay for Simultaneous Qualification of Midazolam, 1'-Hydroxymidazolam, and 4-Hydroxymidazolam by Liquid Chromotography Coupled to Tandem Mass-Spectroscopy." Journal of Chromotography B. 878(19):1629-1633. June 2010.

Dring, Ann M., Linnea E. Anderson, Saima Qamar and Matthew A. Stoner. "Rational Quantitative Structure-Activity Relationship (RQSAR) Screen for PXR and CAR Isoform-Specific Nuclear Reception Ligands." Chemico-Biological Interactions. 188(3):512-552. December 2010.

El-Kattan, Ayman.  SEE: Varma, Manthena V. S.

Elliott, Richard L., Kimberly O. Cameron, Janice E. Chin, Jeremy A.  Bartlett, Elena E. Beretta, Yue Chen, Paul Da Silva, Jardine, Jeffrey S. Dubins, Melissa L. Gillaspy, Diane M. Hartgrove, Amit S. Kalgutkar, Janet A. LaFlamme, Mary E. Mae, Kelly A. Martin, Tristan S. Maurer, Nancy A. Nardone, Robert M. Oliver, Dennis O. Scott, Dexue Sun, Andrew G. Swick, Catherine E. Trebino and Yingxin Zhang. "Discovery of N-benzyl-2-[4S)-4-(1H-indol-3-ylmethyl)--5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triaxolo[4,3-a][1.5] Benzodiazepin-6-yl]-N-isopropylac etamide, an Orally Active, Gut-Selective CCK1 Receptor Agonist for the Potential Treatment of Obesity." Bioorganic & Medicinal Chemistry Letters. 20(22):6796-6801. November 15, 2010.

Eng, H., M. Niosi, T. S. McDonald, A. Wolford, Y. Chen, S. T. M. Simila, J. N. Bauman, J. Warmus and A. S. Kalgutkar. "Utility of the Carboxlesterase Inhibitor Bis-para-nitrophenylphosphate (BNPP) in the Plasma Unbound Fraction Determination for a Hydrolytically Unstable Amide Derivative and Agonist of the TGR5 Receptor." Xenobiotica. 40(6):369-380. June 2010.

Fueyo, Joanna L.  SEE also: Vincent, James; Wang, Qinghua.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Automatically Determining Ideal Treatment Plans for Complex Neuropsychiatric Conditions. U.S. Patent Application No.20100010831. January 14, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Automatically Developing Neuropsychiatric Treatment Plans Based on Neuroimage Data. U.S. Patent Application No.2010010827. January 14, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Differential Diagnosis of Neuropsychiatric Conditions. Japanese Patent Office. JP20100017519 (A). January 28, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Differential Diagnosis of Neuropsychiatric Conditions. Canadian Patent Application CA26555064 (A1). January 8, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Differential Diagnosis of Neuropsychiatric Conditions. European Patent Office (EPO). EP2144180(1). January 13, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Differential Diagnosis of Neuropsychiatric Conditions. Japanese Patent Office. JP4416828 (B2). February 17, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Differential Diagnosis of Neuropsychiatric Conditions. U.S. Patent Application No.20100010316. January 14, 2010.

Fueyo, Joanna L., R. L. Angell, R. R. Friedlander and J. R. Kraemer. Determination of Neuropsychiatric Therapy Mechanisms of Action. U.S. patent Application. No.20100010363. January 14, 2010.

Gilligan, Timothy D., Jerome Seidenfeld, Ethan M. Basch, Laurence H. Einhorn, Timothy Fancher, David C. Smith, Andrew J. Stephenson, David J. Vaughn, Roxanne Cosby and Daniel F. Hayes. "American Society of Clinical Oncology Clinical Practice Guidelines on Uses of Serum Tumor Markers in Adult Males With Germ Cell Tumors." Journal of Clinical Oncology. 28(20):3378-3394. July 10, 2010.

Henning, Susanne M., Navindra P. Seeram, Yanjun Zhang, Luyi Li, Kun Gao, Ru-Po Lee, David C. Wang, Alona Zerlin, Hannah Karp, Gail Thames, Jenny Kotterman, Zhaoping Li and David Heber. "Strawberry Consumption Is Associated With Increased Antioxidant Capacity in Serum." Journal of Medicinal Food. 13(1):116-122. 2010.

Holmes, Roger S., Matthew W. Wright, Stanley J. F. Laulederkind, Laura A. Cox, Masakiyo Hosokawa, Teruko Imai, Shun Ishibashi, Richard Lehner, Masao Miyazaki, Everett J. Perkins, Philip M. Potter, Matthew R. Redinbo, Jacques Robert, Tetsuo Satoh, Tetsuro Yamashita, Bingfan Yan, Ttsuryoshi Yokoi, Rudolf Zechner and Lois J. Maltais. "Recommended Nomenclature for Five Mammalian Carboxylesterase Gene Families: Human, Mouse, and Rat Genes and Proteins." Mammalian Genome. 21(9-10):427-441. September-October 2010.

Hu, Susie, Fatemeh Aklaghi, Shripad Chitnis, Ritche Chiu, Subil Go, Preete Roul, Michael Steffes, J. Dawn Abbott, Lanie Dworkin and Andrew Bostom. "Comparison of Plama Clearance of Iodixanol During Versus After Angiography (Research Letter)." American Journal of Kidney Diseases. 56(6):1219-1220. December 2010.

Ionita, I. A. and F. Akhlaghi. "Quantification of Unbound Prednisolone, Prednisone, Cortisol and Cortisone in Human Plasma by Ultrafication and Direct Injection Into Liquid Chromotography Tandem Mass Spectrometry." Annals of Clinical Biochemistry. 47(4):350-357. July 2010.

Jain, Vipin, Bongsup Cho,  Satyakkam Patnaik, Vaidnathan Ganson, Eve Darien and Alexander D. Mackerel. "Long-Range Sequence Effect on the Arylamine-Induced Conformational Heterogeneity (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  TOSI-115. August 2010.

Jain, Vipin, Fenting Liang, Satyakkam Patnaik, Varsha Biyyala and Bongsup Cho. "Unusual DNA Sequence Effect on the Aminobiphenyl-Induced Conformational Heterogeneity (Abstract)." Clinical Research in Toxicology. 23(1) 90. January 2010.

Jang, Thomas L., Justin E. Bekelman, Yihai Liu, Peter B. Bach, Ethan M. Basch, Elena B. Elkin, Michael J. Zelefsky, Peter T. Scardine, Colin B. Begg and Deborah Schrag. "Physician Visits Point to Treatment for Clinically Localized Prostate Cancer." Archives of Internal Medicine. 170(5):440-450. March 8, 2010.

Jay, Gregory D.  SEE also: Coles, Jeffrey M.; Kobayashi, Leo; Wei, L.; Zhao, C. F.

Jay, Gregory D., Braden C. Fleming, Bryan A. Watkins, Karen A. McHugh, Scott C. Anderson, Ling. X. Zhang, Erin Teeple, Kimberly A. Walker and Khalid A. Elsaid. "Prevention of Cartilage Degeneration and Restoration of Chindorprotection  by Lubricin Tribosupplementation in the Rat Following Anterior Cruciate Ligamernt Transection." Arthritis and Rheumatism. 62(8):2382-239. August 2010.

Jutooru, I., G. Chadalapaka, M. Abdelrahim, M. R. Basha, I. Samudio, M. Konopleva, M. Andrweeff and S. Safe. "Methyl 2-Cyano, 12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a." Molecular Pharmacology.78(2):226-236. August 2010.

Kalgutkar, Amit S.   SEE also: Aiello, Robert J.; Elliott, Richard L.; Eng, H.; Litchfield, John; Schneider, R. P.; Southers, James A.

Kalgutkar, Amit S., D. A. Griffith, T. Ryder, H. Sao, Z. Miao, J. N. Bauman, M. T. Diduik, K. S. Frederick, S. X. Zhao, C. Prakash, J. R. Soglia, S. W. Bagley, B. M. Bechle, R. M. Kelley, K. Dirico, M. Zawistoski, J. Li, R. Oliver, A. Guzman-Perez, K. K. C. Liu, D. P. Walker, J. W. Benbow and J. Morris. "Discovery Tactics to Mitigate Toxicity Risks Due to Reactive Metabolite Formation With 2-(2-Hydroxyaeyl)-5-(trifluormethyl0pyrido[4,3-d]pyrimidiin-4(3H)-one Derivatives, Potent Calcium-Sensing Receptor Antagonists and Clinical Candidate(s) for the Treatment of Osteoporosis." Chemical Research in Toxicology. 23(6):1115-1126. June 21, 2010.

Karakatsani, Marianthi, Mahendra Dedhiya and Fotios M. Plakogiannis. "The Effect of Permeation Enhancers on the Viscosity and the Release Profile of Transdermal Hydroxypropl Methylcellulose Gel Formulations Containing Diltiazem HCI." Drug Development and Industrial Pharmacy. 36(10):1195-1206. October 2010.

Karhu, David, Gerhard Groenewood, Maria Potgieter and Diane Mould. "Dose Proportionality of Once-Daily Trazodone Extended-Release Caplets Under Fasting Conditions." Journal of Clinical Pharmacology. 50(12):1438-1449. December 2010.

King, Roberta S. "Book Review: The Biochemistry of Drug Metabolism: Conjugations of Metabolism: Conjugations of Metabolism, Influencing Factors Edited by Bernard Testa and Stephanie D. Kraemer." Journal of Medicinal Chemistry.  53(17):6524. September 9, 2010.

Kobayashi, Leo, David G. Lindquist, Ilse M. Jenouri, Kevin M. Dushay, Donna Haze, Elizabeth M. Sutton, Jessica L. Smith, Robert J. Tubbs, Frank L. Overly, John Foggle, Jennifer Dunbar-Viveiros, Mark S. Jones, Scott T. Marquette, David L. Werner, Mary R. Cooper, Peggy B. Martin, Dominick Tammaro and Gregory D. Jay. "Comparison of Sudden Cardiac Arrest Resuscitation Performance Data Obtained From In-Hospital Incident Chart Review and In Situ High-Fidelity Medical Simulation." Resuscitation. 81(4):463-471. April 2010.

Kobayashi, L., L. A. Sweeney, A. C. Cousins, K. S. Bertsch, F. G. Gardiner, N. M. Tomaselli, R. M. Boss III, F. J. Gibbs and G. D. Jay. "Emergency Department Personnel Perception of Their Role in Patient Experience (Abstract)." Annals of Emergency Medicine. 56(3,Suppl):S12. September 2010.

Kobayashi, Leo, Jennifer A. Dunbar-Viveiros, Bethany A. Sheahan, Megan H. Rezendes, Jeffrey Devine, Mary R. Cooper, Peggy B. Martin and Gregory D. Jay. "In Situ Simulation Comparing In-Hospital First Responder Sudden Cardiac Arrest Resuscitation Using Semiautomated Defibrillators and Automated External Defibrilators." Simulation in Healthcare. 5(2):82-90. April 2010.

Kovoor, Abraham.  SEE: Celver, Jeremy P.; Masuho, Ikuo; Rochdi, Moulay D.; Sharma, Meenakshi.

Krewski, Daniel, Daniel Acosta, Jr., Melvin Anderson, Henry Anderson, John Bailar III, Kim Boekelheide, Robert Brent, Gail Charnley, Vivian G. Cheung, Sidney Green, Jr., Karl T.Kelsey, Nancy I. Kerkvliet, Abby A. Li, Lawrence McCray, Otto Meyer, Reid D. Patterson, William Pennie, Robert A. Scala, Gina A. Solomon, Martin Stephens, James Yager, Lauren Zeise and the Staff of Faculty Conventions for Tocity Testing and Assessment of Environmental Agents. "Toxicity Testing in the 21st Century: A Vision and a Strategy." Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13(2-4):51-138. 2010.

Ku, Warren W., Frank Pagliusi, George Foley, Alfred Roesler and Thomas Zimmerman. "A Simple Orchidometric Method for the Preliminary Assessment of Maturity Stats in Male Cynomolgus Monkeys (Macaca fascocularis) Used for Nonclinical Safety Studies." Journal of Pharmacological and Toxicological Methods. 61(1):32-37. January-February 2010.

Li, Liya, Daniel Woolridge, Ritchie Seing, John Jennings, Geneive E. Henry and Navindra Seeram. "Flavonoids and a Stilbene Brom Triadenum fraseri (Spach) Gleason." Biochemical Systematics and Ecology. 38(5):1074-1076. October 2010.

Li, Liya, Molly MacDonald and Navindra Seeram. "Maple Syrup Constituents Beyond Macronutrients: Antioxidant Phenotics in Canadian Maple Syrup  (Abstract)." Abstracts of Papers of the American Chemical Society. 2010.  AGFD-41.

Li, Liya and Navindra Seeram. "Maple Syrup Phytochemicals Include Ligands, Coumarins, a Stilbene, and Other Previously Unreported Antioxidant Phenolic Compounds." Journal of Agricultural and Food Chemistry. 58(22):11673-11679. November 24, 2010.

Li, Liya and Navindra Seeram. "Sugar Maple (Acer saccharun) Photochemicals: Antioxidant, Antibacterial, and Cytotoxicity Properties (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  AGFD-24.

Li, Liya, Daniel Woolridge, John Jennings, Ritchie Seing, Geneive E. Henry and Navindra Seeram. "Phytochemical's in Fraser's Marst St. John's Wort (Triadenum fraseri) (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  AGFD-148.

Li, Y., Q. Shen, H.-T. Kim, R. P. Bissonette, W. W. Lamph, B. Yan and P. H. Brown. "Therexinoid Bexarotene Represses Cyclin D1 Transcription by Inducing the DEC2 Transcriptional Represser." Breast Cancer Research and Treatment. 2010.

Liang, Fengting and Bongsup P. Cho. "Enthalpy-Entropy Contribution to Carcinogen-Induced DNA Conformational Heterogeneity." Biochemistry. 49(2):259-266. January 19, 2010.

Litchfield, John, Raman Sharma, Karen Atkinson, Kevin J. Filipski, Stephen W. Wright, Jeffrey A. Pfefferkorn, Beijing Tan, Rachel E. Kosa, Benjamin Stevens, Meihua Tu and Amit S. Kalgutkar. "Intrinsic Electrophilicity of the 4-methylsulfonyl-2-pyridone Scaffold in Glucokinase Activators: Role of Glutathione-S-Transferases and in Vivo Quantitaiion of a Glutathione Conjugate in Rats." Bioorganic & Medicinal Chemistry letters. 20(21):6262-6267. November 1, 2010.

Lu, Wei.  SEE also: Melancon, M.

Lu, W., Q. Huang, G. Ku, X. Wen, M. Zhou, D. Guzatov, P. Brecht, R. Su, A. Oraevsky, L. V. Wang and C. Li. "Photoacopustic Imaging of Living Mouse Brain Vasculature Using Hollow Gold Nanospheres." Biomaterials. 31:2617-2626. 2010.

Lu, W., G. Zhang, R. Zhang, L. G. Flores II, Q. Huang, J. G. Gelovani and C. Li. "Tumor Site-Specific Silencing of NF-KB p65 by Targeted Hollow Gold Nanospheres-Mediated Photothermal Transfection." Cancer Research. 70:3177-3188. 2010.

Ma, Hang, Liya Li and Navindra P. Seeram. "Phenolics From Cornus amomum Mill. Fruit." Biochemical Systematics and Ecology. 38(5):1083-1084. October 2010.

Ma, Hang, Liya Li and Navindra P. Seeram. "Phytochemicals in Silky Dogwood (Cornusamomum) Fruit (Abstract)." Abstracts of Papers of the American Chemical Society. AGFD 144. August 2010.

Ma, Hang, Liya Li and Navindra P. Seeram. "Phytochemicals in Winged Sumac (Rhus copallinum) Fruit (Abstract)."  Abstracts of Papers of the American Chemical Society. March 21-25,  2010.  AGFD-147.

MacDonnell, C. P., A. M. DeAngelis-Chichester and C. O. Chichester. "The Role of Human Patient Simulation in Pharmacy Education."  IN: Proceedings of the ICERI2010 Conference, 15th-17th November, Madrid Spain.   p.3611-3613.

Mandel, Deendayal and Keykavous Parang. "Self-Assessing of Cyclip Peptides and Potential Transporters (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  ORG-107.

Masuho, Ikuo, Jeremy Celver, Abraham Kovoor and Kirill A. Martemyanov. "Membrane Ancher R9AP Potentiates GTPase-Accelerating Protein Activity of RGS11-G Beta (5) Complex and Accelerates Inactivation of the mGluR6-G(o) Signaling." Journal of Biological Chemistry. 285(7):4781-4787. February 12, 2010.

Matharu, Jyothi, Jun Oki, David R. Worthen, Quentin R. Smith and Peter A. Crooks. "Regiospefic and Conformationally Restrained Analogs of Melphalan and dl-2-NAM-7 and Their Affinities for the Large Neutral Amino Acid Transporter (System LAT1) of the Blood-Brain Barrier." Bioorganic & Medicinal Chemistry Letters. 20(12):3688-3691. June 2010.

Mehta, A., K. Boekelheide and M. Sigman. "Reliability of Anogenitsal Distance Measurement as an Assay of Male Fertility (Abstract)." Journal of Andrology. 44-45. Suppl.S. May-April 2010.

Melancon, M., W. Lu, Q. Huang, P. Thapa, D. Zhou, C. Ng and C. Li. "Targeted Imaging of Tumor-Associated M2 Macrophages Using a Macromolecular Contrast Agent PG-Gd-NIR813." Biomaterials. 31:6567-6573. 2010.

Menini, Srinivasarao, Fentling Liang and Bongsup P. Cho. "Erratum to 'Examination of the Long-Range Effects of Aminofluorene-Induced Conformational Heterogeneity and Its Relevance to the Mechanism of Translesional DNA Synthesis.' [J.Mol.Biol. 366:1387-1400. 2007." Journal of Molecular Biology. 398(5):7686. 21 May 2010.2010.

Mould, Diane R.  SEE also:  Karhu, David.

Mould, Diane R. and Bruce Green. "Pharmacokinetics and Pharmacodynamics of Monoclonal Antibiodies Concepts and Lessons for Drug Development." Biodrugs. 24(1):23-39. 2010.

Mould, Diane R. and Bill Frame. "Population Pharmacokinetic-Pharmacodynamic Modeling of Biological Agents: When Modeling Meets Reality." Journal of Clinical Pharmacology. 50(Suppl.9):S91-S100. September 2010.

Mularski, Richard A., Margaret L. Campbell, Steven M. Asche, Bryce B. Reeve, Ethan Basch, Terri L. Maxwell, J. Russell Hoverman, Joanne Curn, Steve B. Clauser, Claire Snyder, Hsien Seow, Albert Wu. and Sydney Dy. "A Review of Quality of Care Evaluation for the Palliation of Dyspnea." American Journal of Respiratory and Critical Care Medicine. 181(6):534-538. 2010.

Mumper, Russell J., Michael A. Bell, David R. Worthen, Richard A. Cone, Gareth R. Lewis, Jeremy R. A. Paull, Thomas R. Moench.  "Formulating a Sulfonated Antimicrobial Dendrimer in a Vaginal Microbicidal Gel Having Dual Mechanisms of Action."  Drug Development and Industrial Pharmacy. 35:515-24, 2010.

Narwal, Rajesh, Fatemeh Aklaghi, Anders Asberg, Monica Hermann and Sara E. Rosenbaum. "Development of a Population Pharmacokinetic Model for Atorvastation Acid And Its Lactone Metabolite." Clinical Pharmacokinetics. 49(10):693-702. October 1, 2010.

Omar, Raed, Liya Li,, Amanda Cirello and Navindra Seeram. "Compounds for Eugenia jambelana (Jamun) Berries Beyond Anthocyamins  (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  AGFD-158.

Ozolins, Terence R. St. "Cyclophosphamide and the Teratology Society: An Awkward Marriage." Birth Defects Research. Pt. B Developmental and Reproductive Toxicology. 89(4):289-299. August 2010.

Pabla, Dimple, Fatemeh Akhlaghi and Hossein Zia. "Intestinal Permeability Enhancement of Levothyroxine Sodium by Straight Chain Fatty Acids Studied in MDCK Epithelial Cell Line." European Journal of Pharmaceutical Sciences. 40(5):466-472. August 2010.

Pacheco, S., C. Schoerl, E. A., Housemna, K. Kelsey, M. Sigman and K. Boekelheide. "Genome-Wide Approaches to Identifying Sperm Biomarkers of Toxicant Exposure (Abstract)." Clinical Pharmacology & Therapeutics. 87(Suppl.1):S77. February 2010.

Parang, Keykavous.  SEE: Agarwal, Hitesh K; Ahmadibeni, Yousef; Chhikara, Bhupendor S.; Mandel, Deendayal;  Penugonda, Suman; Sharma, Deepta; Tiwari, Rakesh.

Parikh, T., M. M. Bommana and E. Squillante. "Efficacy of Surface Change in Targeting Pegylated Nanoparticles of Sul Piride to the Brain." European Journal of Pharmaceutics and Biopharmaceutics. 74(3):442-450. March 2010.

Patniak, Satyakam and Bongsop P. Cho. "Structures of 2-Acetylaminofluorine Modifies DNA Revisited: Insights into Conformational Heterogeneity." Chemical Research in Toxicology. 23(11):1650-1652. November 15, 2010.

Penuganda, Suman, Anil Kumar, Hitesh K. Agarwal, Keykavous Parang and Reza Mehvar. "Synthesis and In Vitro Characterization of Novel Dextran-Methylprednisolone Conjugates With Peptide Linkers: Effects of Linker Length on Hydrolytic and Enzymatic Release of Methylprednisolone and Its Peptidyl Intermediates." Journal of Pharmaceutical Sciences. 99(3):1626-1637.  March 2010.

Raul, S. L., B. Kirthivasan, M. M. Bommana, E. Squillante and M. Sadoqi. "The Formulation, Characterization and In Vivo Evaluation of a Magnetic Carrier for Brain Delivery of NIR Dye." Nanotechnology 21(39):#395102. October 2010.

Rochdi, Moulay D., Gabriel A. Vargas, Eric Carpentier, Genevieve Oligny-Longpre, Stanford Chen, Abraham Kovoor, Stephen E. Gitelman, Stephen N. Rosenthal, Mark von Zastrow and Michael Bouvier. "Functional Characterization of Vasopression Type 2 Receptor Substitution (R1137H/C/L) Leading to Nephrogenic Diabetes Insipidis and Nephrogenic Syndrome of Inappropriate Antidurvesis: Implications for Treatments." Molecular Pharamacology. 77(5):836-846. 2010.

Rosenbaum, Sarah E.  SEE: Narwal, Rajesh.

Schneider, R. P., H. Zhang, L. Mu, A. S. Kalgutkar and R. Bonner. "Utility of Multivariate Analysis in Support of In Vitro Metabolite Identification Studies: Retrospective Analysis Using the Antidepressant Drug Nefazodone." Xenobiotica. 40(4):262-274. April 2010.

Seeram, Navindra P.  SEE also: Adams, Lynn S.;  Asharobi, Omatola; Bolser, Jessica; Henning, Susanne M.; Li, Liya; Ma, Hang; Omar, Raed; Sharma, Meenakshi.

Seeram, Navindra P. "Recent Trends and Advances in Berry Health Benefits Research." Journal of Agriculture and Food Chemistry. 58(7):3869-3870. April 14, 2010.

Shaikh, Zahir A.  SEE: Vincent, James; Yu, Xinyuan.

Sharma, Deepta, Raman K. Sharma, Sumati Bhatia, Rakesh Tiwari, Deendayal Mandel, Jessica Lehmann, Keykavous Parang, Carl E. Olsen, Virinda S. Pamer and Ashol K. Prasad. "Synthesis, SRC Kinase Inhibiting and Anticancer Activities of 1-Unsubstitched 3-(N-alkyl-N-phenylamine) Propane-2-Oils." Biochimie.  92(9):1164-1172. 2010.

Sharma, Meenakshi, Liya Li, Jeremy Celver, Caroline Killian, Abraham Kovoor and Navindra Seeram. "Effects of Fruit Ellagitannin Extracts, Ellargic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signalling." Journal of Agriculture and Food Chemistry. 58(7):3965-3969. April 14, 2010.

Shi, Deshi, Dongfang Yang and Bingfang Yan. "Dexamethasone Transcriptionally Increases the Expression of the Pregnane X Receptor and Synergistically Enhances Pyrethroid Esfenvalerate in the Induction of Cytochrom P450 3A23." Biochemical Pharmacology. 80(8):1274-1283. 15 October 2010.

Southers, James A., Jonathan N. Bauman, David A. Price, Paul S. Humphries, Gaytari Balan, John F. Sagal, Tristan S. Maurer, Yan Zhang, Robert Oliver, Michael Herr, David R. Healy, Mei Li, Brendan Kapisno, Gwendolyn D. Fate, G. S. Fate, Keith A. Riccardi, Vishwar M. Paralkar, Thomas A. Brown and A.mitS. Kalgutkar. "Metabolism-Guided Design of Short-Acting Calcium-Sensing Receptor Antagonists." ACS Medicinal Chemistry Letters. 1(5):219-223. August 2010.

Squillante, Emilio.  SEE: Parikh, Tapan; Raul, S. L.

Stoner, Matthew A.   SEE: Dring, Anne M.

Tiwari, Rakesh, Alex Brown, Seetha Narramaneni, Gongqin Sun and Keykavous Parang. "Conformationally Constrained Peptides as the Sre SH3 Domain Binding Ligands (Abstract)."  Abstracts of Papers of the American Chemical Society. 2010.  MEDI-230.

Tiwari, Rakesh and Keykavous Parang. "Protein Conjugates of SH3-Domain Ligands and ATP-Competitive Inhibitors as Bivalent Inhibitors of Protein Kinases." ChemBioChem. 2010.

Tiwari, Rakesh, Alex Brown, Seetha Narramaneni, Gonqgin Sun and Keykavous Parang. "Synthesis and Evaluation of Conformationally Constrained Peptide Analogues as the Src SH3 Domain Binding Ligands." Biochemie. 92(9):1153-1163. September 2010.

Udwary, Daniel W.   SEE also: Crooks, Peter A.

Udwary, Daniel W. "Natural Product Combinatorial Biosynthesis: Promises and Realities."  IN: Natural Product Chemistry for Drug Discovery. 2010.  p.299-317.

Undey, Cenk, Sinem Ertunc, Thomas Mistretta and Bryan Looze. "Applied Advanced Process Analytics in Biopharmaceutical Manufacturing: Challenges and Prospects in Real-Time Monitoring on Control." Journal of Process Control. 20(9):1009-1018. October 2010.

Vaidyanathan, V. G. and Bongsup Cho. "Thermodynamic and Real Time Analysis of Aminofluorene-DNA Adduct/Polymerase Interaction at the Replication Fork (Abstract)." Clinical Research in Toxicology. 23(1) 271. January 2010.

Varma, Manthena V. S., R. Scott Obach, Charles Rotter, Howard R. Miller, George Chang, S. J. Steyn, Ayman El-Kattan and Matthew D. Troutman. "Physiochemical Space for Optimum Oral Bioavailability; Contributions of Human Intestinal Absorption and First-Pass Elimination." Journal of Medicinal Chemistry. 53(3):1098-1081. February 11, 2010.

Vickers, Andrew J., Carolene J. Savage, Marawan Shouery, James A. Eastham, Peter T. Scardino and Ethan M. Bausch. "Validation Study of a Web-Based Assessment of Functional Recovery After Radical Prostatectomy." Health and Quality of Life Outcomes. 8:#82. August 5, 2010.

Vincent, James, Benjamin King, Clinton Chichester, Joanna Fueyo, Qinghua Wang, Bruce Kingham, Carolyn Mattingly, Randall D. Dahn, Cecilia Arighi, Marc Farnum Rendino, William Kelley Thomas, Hongzhan Huang, Mihailo Kaplarevic, Douglas Green, Scott Valcourt, Jeff Letourneau, Bruce Segee, Cathy H. Wu, Karl Steiner, Zahir Shaikh, David Weir, Bruce Stanton, Patricia Hand and Judith Van Houten. NECC - North East Cyberinfrastructure Enabling Collaborative Research Through Shared Infrastructure. Published and Presented at NIH, NCRR Third Biennial National IDEA Symposium of Biomedical Research Excellence (NISBRE). June 16-18, 2010.

Wang, Qinghua, Benjamin King, Ceceilia Arighil, Hongzhan Huang, Mihailo Kaplarevic, Bruce Kingham, James Vincent, Randall D. Dahn, Carolyn Mattingly, Clinton Chichester, Joanna Fueyo, William Kelley Thomas and Cathy H. Wu. Skate Genome Project: A Cyber-Enabled Research and Workforce Development. Published and Presented at NIH, NCRR Third Biennial National IDEA Symposium of Biomedical Research Excellence (NISBRE). June 16-18, 2010.

Wang, X. S., Q. L. Shi, C. Lu, E. M. Basch, V. E. Johnson, T. R. Mendoza, G. M. Mobley and C. S. Cleeland. "Prognostic Value of Symptom Burden for Overall Survival in Patients Receiving Chenoth for Advanced Nonsmall Cell Lung Cancer." Cancer. 116(1):137-1445. January 1, 2010.

Wang, Y., J. Wang, R. D. Finkelman, H. Jou, C. T. Azumaya, R. Mosqueda-Garcia and B. K. Birmingham. "Effect of CYP2C19 Polymorophism on the Pharmacokinetics of Rousvastatin in Healthy Taiwanese Subjects (Abstract)." Clinical Pharmacology & Therapeutics. 87(Suppl.1):S22. February 2010.

Wei, Lai, Braden C. Fleming, Xiajuan Sun, Erin Teeple, Wesley Wu, Gregory D. Jay, Kkaled A. Elsaid, Junming Lubu, Jason T. Machan and Qian Chen. "Comparison of Differential Biomarkers of Osteoarthritis With and Without Posttraumatic Injury in the Hartley Guinea Pig Model." Journal of Orthopaedic Research. 28(7):900-906. July 2010.

Worthen, David R.  SEE: Asharobi, Omatola;  Matharu, Jyothi; Mumper, Russell J.

Worthen, David R., Simon Bristow and Philip Cocks. Process of Making  Aripiprazole Particles. US Patent 7,507,823, 2009.

Yamasaki, Hideki, Moses A. Sandrof and Kim Boekelheide. "Suppression of Radiation-Induced Testicular Germ Cell Apotosis by 2,5-hexanedion Pretreatment. 1. Histopathological Analysis Reveals Stage Dependence of Attenuated Apotosis." Toxicological Sciences. 117(2):449-456. October 2010.

Yan, Bingfang.  SEE: Holmes, Roger S.; Li, Y.; Shi, Deshi; Yang, Jian.

Yang, Jian, Chunshu Hao, Dongfang Yang, Deshu Shin, Xiulong Song, Xinofele Luan, Gany Hu and Bingfang Yan. "Pregnane x Receptor Is Required for Interleukin-6-Mediated Down-Regulation of Cytocrome P450 3A4 in Human Hepatocytes." Toxicology Letters. 68(3):242-247. September 2010.

Ye, Guofeng, Anju Gupta,  Robert DeLuca, Keykavous Parang and Geoffrey D. Bothun. "Bilayer Disruption and Liposome Restructuring by a Homologous Series of Small Arg-Rich Synthetis Peptides." Colloids and Surfaces B: Interfaces. 76(1):76-81. March 1, 2010.

Yu, Xinyuan, Edward J. Filardo and Zahir A. Shaikh. "The Membrane Estrogen Receptor GPR30 Mediates Cadmium-Induced Proliferation of Breast Cancer Cells." Toxicology and Applied Pharmacology. 245(1):83-90. May 15, 2010.

Zawia, Nasser H. and Fernando Cardozo-Pelaez. "An Epigenetic Model for Susceptibility to Oxidative Brain and Alzheimer's Disease."  IN: Aging and Age-Related Disorders. 2010.  p.439-453.

Zhao, Chunfeng, Yu-Long Sun, Ramona L. Kirk, Andrew R. Thoresen, Gregory D. Jay, Steven L. Moran, Kai-Nan An and Peter C. Amadio. "The Effects of a Lubricin-Cintaining Compound on the Results of Flexor Tendon Repair in a Canine Model In Vivo." Journal of Bone and Joint Surgery - American Volume. 92A(6):1453-1461. June 2010.

Zia, Hossein.  SEE: Pabla, Dimple

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