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Faculty Publications
Compiled by Margaret J. Keefe

Faculty Publications 2012

Biomedical & Pharmaceutical Sciences

Adwan, Lina and Nasser Zawia. "A Novel Approach for Lowering Multiple Targets in Alzheimer's Disease (Abstract)." Alzheimer's & Dementia. 8(4,S):716. July 2012.

Agarwal, H. K., G. F. Donal and K. Parang. "Synthesis and Anti-HIV Activities of Conjugates of 3'-fluoro-2',3'-didemythymidine and 3'-azido-2',3'dideoxythymidine." Medicinal Chemistry. 55(6):2672-2687. March 22, 2012.

Agarwal, Hitesh K., Bhupender S. Chhikara, Megrose Quiterio, Gustavo F. Doncel and Keykevous Parang. "Synthesis and Anti-HIV Activities of Glutamate and Peptide Conjugates of Nucleoside Reverse Transcriptase Inhibitors." Drugs. 72(1):49-66. March 22, 2012.

Agarwal, H. K., G. F. Donal and K. Parang. "Synthesis and Anti-HIV Activities of Suramin Conjugates of 3'-fluoro-2',3'-didemythymidine and 3'-azido-2',3'dideoxythymidine." Medicinal Chemistry. 8(2):193-207. March 2012.

Agarwal, Hitesh K., Karen W. Buckheit, Robert W. Buckheit Jr. and Keykavous Parang. "Synthesis and Anti-HIV Activities of Symmetrical Dicarboxylate Esters of Dinucleoside Reverse Transcriptase Inhibitors." Bioorganic & Medicinal Chemistry. 22(17):5451-5454. 1 September 2012.

Agarwal, Hitesh K., Bhupender S. Chhikara, Michael J. Hanley, Guofeng Ye, Gustavo F. Doncel and Keykavous Parang. "Synthesis and Biological Evaluation of Fatty Acyl Ester Derivatives of (-)-2',23'-dideoxy-3-thiacytidne." Journal of Medicinal Chemistry. 55(10):4861-4871.  May 24, 2012.

Ahmad, Aftab.  SEE also: Musharraf, Syd G.; Ng, K. W.; Paliwal, P. R.; Tsze, D. S.; Varma, M. W.; Velmurugan, K.

Ahmad, Aftab and V. K. Sharma. "Early Sub Critical Ischemic Infarction and Delayed Leucoencephalopahty After Carbon Monoxide Poisoning." International Journal of  Emergency Medicine. Suppl.1:33-34. 2-12.

Ahmed, M. S., A. Kovoor, S. Nordman, N. Abu Seman, T. W,. Gu, S. Efendic, K. Brismar, C. G. Ostenson and H. F. Gu. "Increased Expression of Adenylyl Cyclase in Pancreatic Islets and Central Nervous System of Diabetiuc Goto-Kakiozaki Rats: A Possible Regulatory Role in Glucose Homeostasis." Islets. 4(5):343-348. September-October 2012.

Ahmed, Sara, Richard A. Bberzon, Dennis A. Revicki, William R. Lenderking, Carol M. Moinpour, Ethan Basch, Bryce B. Reeve, Albert W. Wu on Behalf of the International Society for Quality of Life Research. "The Use of Patient-Reported Outcomes (PRO) Within Comparative Effectiveness Research: Implications for Clinical Practice and Health care Policy." Medical Care. 50(12):1060-70. December 2012.

Akhlaghi, Fatemeh.  SEE also: Dostalek, Mirosav ; Longato, Frank; Macwan, Joyce S.; Tsze, Daniel S.

Akhlaghi, Fatemeh, Miroslav Dostalek, Pal Falck, Anisha E. Mendoza, Rune Amundsen. Reginald Y. Gohh and Anders Asberg. "The Concentration of Cyclosporine Metabolites Is Significantly Lower in Kidney Transplant Recipients With Diabetes Mellitus." Therapeutic Drug Monitoring. 34(1):38-45. February  2012.

Akelman, Matthew R., Erin Teeple, Jason T. Machon, Joseph J. Crisco, Gregory D. Jay and Braden C. Fleming. "Pendulum Mass Affects the Measurement of Articular Friction Coefficient." Journal of Biomechanics. 2012.

Alashwal,  Hany.  SEE also: Dosunmu, Remi.

Alashwal,  Hany, Remi Dosunma and Nasser H. Zawia. "Integration of Genome-Wide Expression and Mythlation Data: Relevance to Aging and Alzheimer's Disesase."  Neurotoxicoloy. 33(6):1450-1453. December 2012.

Andikyan, Vagan, Youssef Rezk, M. Heather Einstein, Gina Gualtiere, Mario M. Leitao, Jr., Yukiio Sonoda, Nadeem R. Abu-Rustum, Richard R. Barakat, Ethan M. Basch and Dennis S. Chi. "A Prospective Study of the Feasibility and Acceptability of a Web-Based Patient-Reported Outcome System in Assessing Patient Recovery After Major Gynecologic Cancer Surgery (Abstract)." Gynecologic Oncology. 125(Suppl.1):S118. March 2012.

Andikyan, Vagan, Youssef Rezk, M. Heather Einstein, Gina Gualtiere, Mario M. Leitao, Jr., Yukiio Sonoda, Nadeem R. Abu-Rustum, Richard R. Barakat, Ethan M. Basch and Dennis S. Chi. "A Prospective Study of the Feasibility and Acceptability of a Web-Based Patient-Reported Outcome System in Assessing Patient Recovery After Major Gynecologic Cancer Surgery." Gynecologic Oncology. 127(2):273-277. November 2012.

Andrade, Susan E., Robert L. Davis, T. Craig Cheetham, William O. Cooper, De-Kun Li, Thushi Amini, Sarah J. Beaton, S. Dublin, Tarek A. Hammad, Pamala A. Pawloski, Marsha A. Raebel, David H. Smith, Judy A. Staffa, Sengwee Toh, Imma Dashevsky, Katherine Haffenreffer, Kimberly Lane, Richard Platt and Pamela E. Scott. "Medication Exposure in Pregnancy Risk Evaluation Program." Maternal and Child Health Journal. 16(7):1349-1354. October 2012.

Ao, Junping, Jiao Meng, Lui Zhu, Huigen Z. Nie, Chinchen Yang, Jinjjun Lin, Jianre Gu, Quiski Lin, Wwiwoen Long, Xianqun Dong and Chao Li. "Activation of Androgen Receptor Reduces IDI and Promotes Heptocellular Carcinoma Cell Migration and Invasion." Molecular Oncology. 6(5):507-515. October 2012.

Apostolidis, Emmanouil, Liya Li, Bouhee Kang, Chong M. Lee and Navindra Seeram. "Seasonal Influence on Phenotic-Mediated Antihyperglycemic Properties of Canadian Sugar and Red Maple Leaves Using In Vitro Assay Models." Food Science and Biotechnology. 21(3):753-760. June 2012.

Asal, Nicole J.  SEE: Desilets, A. R.

Atkinson, Thomas M., Eric J. Small, Lauren Rogak, Laura Sit, Natalie Barragan, Maury Shaw, Liora Pollick, Sean J. Ryan, Narra Heon, Antonia V. Bennett, Ellen Kaplan, Susan Halabi and Ethan Basch. "Measurement of Affective and Activity Pain Interference Using the Brief Pain Inventory (Abstract)." Annals of Behavioral Medicine. 43(S1):S222. April 2012.

Bao, Z. Y., X. D. Yuan, L. Wang, Y. L. Sun and X. Q. Dong. "The Incidence and Etiology of Community-Acquired Pneumonia in Fever Outpatients." Experimental Biology and Medicine. 237(11):1256-1261. November 2012.

Barbeau, Julie, Genevieve Beland, Navindra Seeram and Tao Yuan. Maple Tree-Derived Products and Uses Thereof. PCT Intl. Appl. 20-120555010 Ai 2012053. 2012.

Basch, Ethan M.  SEE also: Ahmed, Sara; Andikyan, Vaagan; Atkinson, Thomas;  M.; Bennett, Antonio V.; Blinder, Victoria S.; Damast, Shari; Loblaw, D Andrew; Logothestis, Christopher J.; Nam, Robert K.; Romanus, D.; Smith, Timothy J.; Ulbricht, Catherine; Vickers, Andrew J.

Basch, E. "Beyond the FDA PRO Guidance: Steps Towards Integrating Meaningful Patient-Reported Outcomes Into Regulatory Trials and US Drug Labels." Value in Health. 15(3):401-403. May 2012.

Basch, E. M., A. P. Abernathy, C. D. Mullins and M. R. Spencer. "Development of a Guidance for Including Patient Reported Outcomes (PROS) in Late-Phase Adult Clinical Trials of Oncology Drugs for Comparative Effectiveness Research (Abstract)." Value in Health. 15(4):A226. June 2012.

Basch, Ethan, Naomi Aronson, A.alfredBerg, David Flum, Sherrie Gabriel, Steven N. Goodman, Mark Helfand, John P. A. Ioannidis, Michael Lauer, David Meltzer, Brian Mittman, Robin Newhouse, Sharon-Lise Normand, Sebastian Schneeweiss, Jean Slutsky, Mary Tinetti and lyde Yancy. "Methodological Standards and Patient-Centeredness in Comparative Effectiveness Research The PCORI Perspective." JAMA. 307(15):1636-1640. April 18, 2012.

Basch, Ethan M., Amy P. Abernathy, C. Daniels Mullins, B. B. Reeve, M. L. Smith, S. J. Coons, J, Sloan, K. Wenzel, C. Chauhan, W. Eppard, E. S. Frank, J. Lipscomb, S. A., Raymond, M. Spencer and S. Tunis. "Recommendations for Incorporating Patient-Reported Outcomes Into Clinical Comparative Effectiveness Research in Adult Oncology." Journal of Clinical Oncology. 30(334):4249-4255. December 1, 2012.

Basch, Ethan, Thomas K. Oliver, Andrew Vickers, Ian Thompson, Philip Kantoff, Howard Parnes, D. Andrew Loblaw, Bruce Roth, James Williams and Robert K. Name. "Screening for Prostate Cancer With Prostate-Specific Antigen Testing: American Society of Clinical Oncology Provisional Clinical Opinion." Journal of Clinical Oncology. 30(24):3020-3025. August 2012.

Beckford, Floyd A., Jeffrey Thessing, Alyssa Stott, Alvin A. Holder, Oleg G. Poluektov, Liya Li and Navindra P. Seeram. "Anticancer Activity and Biophysical Reactivity of Copper Complexes of 2-(benzo[d][1,3]dioxol-5-ylmethylene)-N-alkylhydrazinecarbothiomides." Inorganic Chemistry Communications. 15:225-229. January 2012.

Bennett, Antonio V., Roxanne E. Jenson and Ethan Basch. "Electronic Patient-Reported Outcome Systems in Oncology Clinical Practice." CA: A Cancer Journal for Clinicians. 2012.

Bhattachaya, Samit K., Gary E. Aspnes, Scott W. Baley, Markus Boehm, Arthur D. Brosius, Leonard Buckbinder, Jeanne S. CHang, Joseph Dibrino, Heather Eng, Kosea S. Frederick, David A. Griffith, Matthew C. Griffor, Christiano R. W. Guimaraes, Angel Guzman-Perez, Seungil Han, Amit S. Kalgutkar, Jacquelyn Klug-McLeod, Carmen Garcia-Irizarry, Jianke Li, Blaise Lippa, David A. Price, James A. Southers, Daniel P. Walker, Liuqing, Jun Xiao, Michael Zawistoski and Xumiao Zhao. "Identification of Novel Series of Pyrazole and Indole-Urea Based DFG-out PYK2 Inhibitors." Bioorganic & Medicinal Chemistry Letters. 22:7523-7529. 2012.

Bhimanagouda S. Patil, Guddadarangawanahally K. Jayapakasha, Kotamballi N. Chidambara Murthy and Navindra P. Seeram. Emerging Trends in Dietary Components for Preventing and Combating Disease. American Chemical Society. (ACS Seminar Series). 2012.  624p.

Bi, Yi-An, E. Kimoto, Larissa Balogh, A. El-Khattan and Y. R. Lei. "Assessment of the Hepatic Disposition and Selectivity of Hepatic Uptake Transporter Substrates in Sandwich-Cultured Immune Hepatocytes. (SCHH)." Drug Metabolism Reviews. 44(51):135-136. 2012.

Bi, Yi-An, E. Kimoto, Smantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chenjie Ji, Katherine S. Fenner, Ayman El-Khattan and Yurong Lai. "In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation." Drug Metabolism and Disposition. 40(6):1085-1092. March 1, 2012.

Bihaqi, Syed and Nasser H. Zawia. "Alzhemier's Disease Biomarkers and Epigenetic Intermediales Following Exposure to Pb In Vtro." Current Alzheimer Research. 9(5):555-562. June 2012.

Bihaqi, Syed W., Axel Schumacher, Bryan Maloney, Debomoy Lahiri and Nasser H. Zawia. "Do Epigenetic Pathways Initiate Late Onset Alzheimer Disease (LOAD): Toward a New Paradigm." Current Alzheimer Research. 9(5):574-588. June 2012.

Blaauboer, B. J., Kim Boekelheide, H. C. Clewell, M. Daneshian, M. M. L. Dingemans, A. M. Goldberg, M. Heneween, J. Jaworska, N. I. Kramer, M. Leistm H. Seibert, E. Testai, R. J. Vandebriel, J. D. Yoger and J. Zurlo. "The Use of Biomarkers for Integrated In Vitro Hazard Estimates Into Risk Assessment for Humans." Altex-Alternatives to Animal Experimentation. 29(4):411-425. 2012.

Blinder, Victoria S., Sujath Patil, Aamaradeep Thind, Allison Diamant, Clifford A. Hudis, Ethan Basch and Rose C. Maly. "Return to Work in Low-Income Latina and Non-Latina White Breast Cancer Survivors: A 3-Year Longitudinal Study." Cancer. 118(6):1664-1674. March 15, 2012.

Boekelheide, Kim.  SEE also: Blaauboer, B. J.; Campion, Sarah N.; Heger, Nicholas; Johnson, K. J.; Pacheco, Sara E.; Saffarini, C. M.; Seifert, Erin L.; Springer, C ecilia; Stephens, Martin L.; Thompson.

Boekelheide, Kim, Bruce Blumberg, Robert E. Chapin, Ila Cote, Joseph H. Graziano, Amanda Janesick, Robert Lane, Karen Lillycrop, Leslie Myatt, J. Christopher States, Kristin A. Thayer, Michael P. Waalkes and John M. Rogers. "Assessment of Circulating Hormones in Regulating Toxicity Studies II. Male Reproductive Hormones." Toxicolic Pathology. 2012.

Boekelheide, K., B. Blumberg, R. E. Chapin, I. Cote, J. H. Graziano, A. Janesick, R. Lane, K. Lillycrop, L. Myatt, J. C. States, K. A. Thayer, M. P. Waalkes and J. M. Rogers. "Predicting Later-Life Outcomes of Early-Life Exposures." Environmental Health Perspectives. 120(10):1353-1361. October 2012.

Boekelheide, Kim and I. Schuppe-Koisten. "SOT/EUROTOX Debate: Biomarkers From Blood and Urine Will Replace Traditional Histopathological Evaluation to Determine Adverse Drug Response." Environmental Health Perspectives. 129(2):249-255. October 2012.

Bose, Sonali, Daniel Schenck, Indrajit Ghosh, Al Hollywood, Ester Maulit and Colleen Ruegger. "Application of Spray Granulation for Conversion of a Nanosuspension into a Dry Powder Form." European Journal of Pharmaceutical Sciences. 47(1):35-43. 30 August 2012.

Campion, S. N., G. D. Cappon, R. E. Chapin, R. T. Jamon, T. R. Winton and W. S. Nowland. "Isoflurane Reduces Motile Sperm Counts in the Sprague-Dawley Rat." Drug and Chemical Toxicology. 35(1):20-24. March 15, 2012.

Campion, S., N. Caitlin, N. Heger, E. V. McDonnell, S. E. Pacheco, C. Saffarini, M. A. Sandrop and Kim Boekelheide. "Male Reprotoxicity and Endocrine Disruption." EXS. 101:315-360. 2012.

Campion, Sarel N., Natasha Caitlin, E. Andres Houseman, Janan Hensley, Yunxai Sui, Kevin W. Gaido, Zhijin Wu and Kim Boekelhiede. "Molecular Alterations Underlying the Enhanced Disruption of Spermatogenesis by 2,5-Hexanedione and Carbendazim Co-Exposure." Reproductive Toxicology. 33(3):382-389. June 2012.

Celver, Jeremy, Meenakshi Sharma and Abraham Kovoor. "D2-Dopamine Receptors Target Regulator of G Protein Singaling 9-2 (RGS9-2) to Detergent-Resistant Membrane Functions." Journal of Neurochemistry. 120(1):56-69. January 2012.

Chapin, Robert E.  SEE also: Boekelheide, Kim; Campion, S. N.; Stanislaus, Dinesh; Van der Laan, J. W.

Chapin, Robert E. and Dianne M. Creasy. "Assessment of Circulating Hormones in Laboratory Toxicity Studies II. Male Reproductive Hormones." Toxicologic Pathology. 40(7):1063-1078. October 2012.

Chen, Yi-Tzai, Deshi Shi, Dongfang Yang and Bingfang Yan. "Antioxidant Sulforaphane and Sensitizer Trinitrobenzene Sulfonate Induce Carboxylesterose-1 Through a Novel Sensitizer Element Transactivated by Nuclear Factor-E2 Related Factor-2." Biochemical Pharmacology. 84(6):864-871. September 2012.

Chen, Y., X. Song, L. Valanegd, A. Vasilen ko, V. More, X. Qiu, W. Chen, Y. Lai, A. Slitt , M. Stoner, B. Yan and R. Deng. "Bile Salt Export Pump Is Dysregulated With Altered Farnesoid x Receptor Isoform Expression in Patients Wirth Hepatocellular Carcinoma Tissues." Hepatology. 2012.

Chichester, Clinton O.  SEE: Zaroogian, Gerald E.

Chhikara, Bhupender S., Rakish Tiwari and Keykavous Parang. "N-Myristolylglutamic Acid Derivative of 3"-Fluoro 3"-Deoxythymidine as an Organogel." Tetrahedron Letters. 53(39):5335-5337. September 2012.

Chhikara, Bhupender S., Deendayal Mandel and Keykavous Parang. "Synthesis, Anticancer Activities, and Cellular Uptake Studies of Lipophilic Derivatives of Doxorubicin Succinate." Journal of Medicinal Chemistry. 55(4):1500-1510. February  23, 2012.

Chichester, Clinton O.  SEE: Jean-Gilles, Dinorah; Patel Jagdishwa; Zaroogian, G. E.

Chistol, G., S. Liu, C. L Hetherington, J. R. Moffitt, S. Grimes, P. J. Jardine and C. Bustamante. "High Degree of Coordination and Division of Labor Among Subunits in a Homomeric Ring ATPase." Cell. 151(5):1017-1028. November 21, 2012.

Cho, Bongsup P.  SEE also: Jain, Anshu; Jain, V.; Sandireni, Anusha; Vaidyanathan, V. G.; Xu, Lifang.

Cho, Bongsup and Norma J. Owens. "The University of Rhode Island College of Pharmacy." Medicine & Health, Rhode Island. 95(9):272. September 2012.

Choi, Hyukjae, Samanthqa J. Mascuch, Francisco A. Villa, Tara Byrum, Margaret E. Teasdale, Jennifer E. Smith, Linda B. Preskitt, David C. Rowley, Lena Gerwick and William H. Gerwick. "Honaucins A-C, Potent Inhibitors of Inflammation and Bacterial Quorum Sensing: Synthetic Derivations and Structure-Activity Relationships." Chemistry & Biology. 19(5):589-598. May 2012.

Cole, Susan, Sharan Bagal, Ayman El-Kattan, Katherine Fenner, Tanya Hay, Sarah Kempshall, Graham Lunn, Manthena Varma, Paul Stupple and William Speed. "Full Efficacy With No CNS Side-Effects: Unachievable Panacea or Reality? DMPK Considerations in Design of Drugs With Limited Brain Penetration." Xenobiotica. 42(1):11-27. January 2012.

Conca, Addison J.and David R. Worthen. "Nonprescription Drug Abuse." Journal of Pharmacy Practice. 25(1):13-21. February 2012.

Damast, Shari, Kaled M. Alektiar, Shari Goldfarb, nne. Eaton, Sujata Patil, Jeffrey Mosenkis, Antonia Bennett, Thomas Atkinson, Elizabeth Jewell, Mario Leitao, Richard Barakat, Jeanne Carter and Ethan Basch. "Sexual Functioning Among Endometrial Cancer Patients Treated With Adjuvant High-Dose-Rate Intra-Vaginal Radiation Therapy." International Journal of Radiation Oncology Biology Physics. 84(2):E187-E193. October 1, 2012.

Dao, C., W. Zhao, M. Karim, Marta Gomez-Chiarri, D. Nelson and D. Rowley. " Investigation of Interactions Between Host, Pathogens, and Probiotic Bacteria (Abstract)." Planta Medica. 78(11):1163. August.

Davis, Richard J.  SEE: Andrade, Susan E.; Li, Y.; Tsang S. H.; Wert, K. J.; Zijlstra, Albert A.

Deng, Ruitang.  SEE also: Chen, Y.; Yang, D.

Deng, Ruitang.  "Pharmacy Research at URI: Bile Acids and Bile Salt Export Pump: Physiology and Pathology." Medicine and Health, Rhode Island. 95(9):290-291. September 2012.

Deng, Ruitang. "A Review of the Hypoclycemic Effect of Five Commonly Used Herbal Food Supplements." Recent Patents on  Food Nutrition and  Agriculture. 4(1):50-60. April 1, 2012.

Desilets, A. R., N. J. Asal and K. C. Dunican. "Considerations for the Use of Proton-Pump Inhibitors in Older Adults." Consult. Pharm. 27(2):114-120. February 2012.

Di, Li, Christopher Keefer, Dennis O. Scott, Timothy J. Strelevitz, Genge Chang, Yi-An Bi, Yurang Lai, Jonathan Dickworth, Katherine Fenner, Matthew Troutman and R. Scott Obach. "Mechanistic Insights From Comparing Intrinsic Clearance Values Between Human Liver Microsomes and Hepatocytes to Guide Drug Design." European Journal of Medicinal Chemistry. 57:441-448. November  2012.

Di, Li, P. Trapa, R. Scott Obach, Karin Atkinson, Yi-An Bi, Angela C. Wolford, Beying Tan, Thomas S. McDonald, Yurong Lai and Larry M. Tremaine. "A Novel Relay Method for Determining Low-Clearance Values." Drug Metabolism and Disposition. 40(9):1860-1865. September 2012.

Donepudi, Ajay C., Lauren M. Aleksunes, Maureen V. Driscoll, Navindra P. Seeram and Angela L. Slitt. "The Traditional Ayurvedic Medicine, Eugenia jambolana (Jamun fruit), Decreases Liver Inflammation, Injury and Fibrosis During Cholestasis." Liver International. 32(4):560-573. April 2012.

Dong, Xiaoqun.  SEE: Ao, J. P.; Bao, Z. Y.; Gu, Mingliang; Guo, Shujie.

Dostalek, Miroslav, Wai-Jung Sam, Konrad R. Paeren, Joyce S. Macwan, Auginald Y. Gohm and Fatemeh Akhlaghi. "Diabetes Mellitus Reduces the Clearance of Atorvastatin-Lactone." Clinical Pharmacologist. 51(9):591-606. September 1, 2012.

Dostalek, M., W. Sam and Fatemeh Akhlaghi. "Diabetes Mellitus Reduces the Clearance of Atorvastatin-Lactone: The Results of a Population Pharmacokinetic Analysis and Ex Vivo Studies Using Livers From Diabetic Donors (Abstract)."  Clinical Pharmacology & Therapeutics. 91(S1):S88. March 2012.

Dostalek, M., W. Sam, K. R. Paryani, J. S. Macwan, R. Y. Gohn and Fatemeh Akhlaghi. "Diabetes Mellitus Reduces the Clearance of Atorvastatin-Lactone: The Results of a Population Pharmacokinetic Analysis in Renal Transplant Recipients and In Vitro Studies Using Human Liver Microsomes." Clinical Pharmacokinetics.  51(9):591-606. 2012.

Dostalek, Miroslav, Fatemeh Akhlaghi and Martina Puzanovava. "Effect of Diabetes Melitus on Pharmacokinetic and Pharmacodynamic Properties of Drugs." Clinical Pharmacokinetics. 51(8):481-499. August 1,  2012.

Dostalek, M., R. Y. Gogh and Fatemeh Akhlaghi. "Inosine Monophosphate Dehydrogenase (IMPDH) Gene and Protein Expression and Activity Is Markedly Lower in Kidney Transplant Recipients With Diabetes Mellitus (Poster Session Abstract)." Clinical Pharmacology & Therapeutics. 91(S1):S87-S88. March 2012.

Dosunmu, Remi, Hany Alashwal and Nasser H. Zawia. "Genome-Wide Expression and Methylation Profiling in the Aged Rodent Brain Due to Early-Life Pb Exposure and Its Relevance to Aging." Mechanisms of Aging Development. .113(6):453-443. June  2012.

Drewniak, Elizabeth I., Gregory D. Jay, Braden C. Fleming, Ling Zhang, Matthew L. Warman and Joseph J. Crisco. "Cyclic Loading Increases Friction and Changes Cartilage Surface Integrity in Lubricin-Mutant Mouse Knees." Arthritis and Rheumatism. 287(5):465-473. February 2012.

El-Agnaf, Omar M.  SEE: Fauvet, B.; Gaugler, M. N.; Gorostidi, Ana; O'Dowd, S. T.; Paleologu, K. E.

El-Khattan, Ayman.  SEE: Bi, Yi-An; Cole, Susan; Feng, B.; Jones, Hannah M.; Kimoto, Emi; Kimoto, E.; Lai, Y.; Pfefferkorn, Jeffrey. A.; Varma, Manthena V. S.

Elsaid, K. A., L. Zhang, K. Waller, J. Tofte, E. Teeple, B. C. Fleming and G. D. Jay. "The Impact of Forced Joint Exercise on Libricin Biosynthesis From Articular Cartilage Following ACL Transection and Intra-articular Lubricin's Effect in Exercised Joints Following ACL Transection." Osteoarthritis and Cartilage. 20(8):940-948.  August 2012.

Elshafeey, Ahmed H., Yassin E. Hamza, Soad Y. Amion and Hossein Zia. "In Vitro Transdermal Permeation of Fenoterol Hydrobromide." Journal of Advanced Research. 3(2):125-132. April 2012.

Espinosa, Aveline, Aaron M. Socha, Erica Ryke and David C. Rowley. "Antiamoebic Properties of the Actinomycete Metabolites Echinomycin A and Tirandamycin A." Parasitology Research. 111(6):2473-2477. December 2012.

Fauvet, Bruce, Martial K. Mbefo, Mohamed-Bilal Fares, Carole Desobry,  Sarah Michael, Mustafa T. Ardah, Elpida Tskia, Phillippe Coune, Michael Prudent, Niels Lion, David Eliezer, Darren J. Moore, Bernard Schneider, Patrick Aebischer, Omar M. El-Agnaf, Eliezar Masliah and Hilal A. Lashuel. "Alpha-Synuclein in Central Nervous System and From Erythrocytes, Mammalian Cells, and Eschericia coli Exists Predominately as Disordered Monomer." Journal of Biological Chemistry. 287(19):15345-15364. May 4, 2012.

Feng, B., A. F. El-Khattan and Z. A. Radi. "Renal Transporters in Drug Disposition, Drug-Drug Interactions, and Nephrotoxicity."  IN: Current Protocol Toxicology. Wiley. 2012.  p.23.3.1-15.

Forschner-Dancausse, S., K. LaPlante, D. C. Smith and D. C. Rowley. "Going Deep for Drug Discovery: An Ocean to Bedside Approach to Explore Sub-Seafloor Microbes for the Next Generation of Antibiotics." Medicine and Health, Rhode Island. 95(9):292-293. September 2012.

Gao, Hongyang and R. Scott Obach. "A Simple Liquid Chromotography-Tandem Mass Spectrometry Method to Determine Relative Plasma Exposures of Drug Metabolites Across Species for Metabolite Safety Assessments (Metabolites in Safety Testing). II. Application to Unstable Metabolites." Drug Metabolism and Disposal. 40(7):1290-1296. March 28, 2012.

Gaugler, Meret Nora, Ozgur Genc, Wojciesk Bobela, Sofa Mohanna, Mustafa Taleb Ardah, Omar Mukktar El-Agnaf, Marco Cantoni, Jean-Charles Bensadoiun, Ralf Schneggenburger, Graham W. Knott, Patrick Aebischer and Bernard Laurent Schneider. "Nigrostriatal Overabundance of Alpha-Synuclein Leads to Decreased Vesicle Density and Deficits in Dopamine Release That Correlate With Reduced Motor Activity." Acta Neuropathology. 123(5):653-669. May 2012.

Gerwick, Lena, Paul Boudreau, Hyukjae Cho, Samantha Mascuch, Francisco A. Villa, Marcy J. Balunas, Karla L. Malloy, Margaret E. Teasedale, David C. Rowley and William H. Gerwick. "Interkingdom Signaling by Structurally Related Cyanobacterial and Algal Secondary Metabolites." Phytochemistry Reviews. 2012: 1-7.

Ghosh, Indrajit, Daniel Schenck, Sonali Bose and Colleen Ruegger. "Optimization of Formulation and Process Parameters for the Production of Nanosuspension by Wet Media Milling Technique: Effect of Vitamin E TPGS and Nanocrystal Particle Size on Oral Absorption." European Journal of Pharmaceutical Sciences. 47(4):718-728. 20 November 2012.

Gobburu, Jogarao.  SEE: Jin, Yuyan; Mehroto, Shailly; Perlstein, Todd S.; Rogers, H. L.;  Wang, Yaning.

Gonzalez-Sarrias, Tao Yuan and Navindra P. Seeram. "Anticancer and Structure Activity Related (SAR) Studies of Maple Gallotannins (Abstract)." Abstracts of Papers of the American Chemical Society. 2012.  AGFD-153.

Gonzalez-Sarrias, Antonio, Liya L. and Navindra P. Seeram. "Anticancer Effects of Maple Syrup Phenolics and Extracts on Proliferation, Apoptosis, and Cell Cycle Arrest of Human Colon Cells." Journal of Functional Foods. 4(1):185-196. January 2012.

Gonzalez-Sarrias, Tao Yuan and Navindra P. Seeram. "Anticancer Studies of Gallotannins From Maple (Acer) Spp (Abstract)." Planta Medica. 78(11):1214. August  2012.

Gonzalez-Sarrias, Antonio, Tao Yuan and Navindra P. Seeram. "Cytotoxicity and Structure Activity Relationship Studies of Maplexins A-1 Gallotannins From Red Maple (Acer Rubrum)." Food and Chemical Toxicology. 50(4):1369-1376. February 23, 2012.

Gonzales-Sarrias, Antonio, Liya Li and Navindra P. Seeram. "Effects of Maple (Acer) Plant Part Extracts on Proliferation, Apoptosis and Cell Arrest of Human Tumorigenic and Non-Tumorigenic Colon Cells." Psychotherapy Research. 50(5):1369-1376. July 2012.

Gorostidi, Ana, Alberto Bergareche, Javier Ruiz-Martinez, Jose F. Mart-Masso, Maria Cruz, Shiji Varghese, Mohamed M. Qureshi, Fatimah Alzahmi, Abdulmonem Al-Hayani,  Adolfo Lopez de Munain and Omar M. A. El-Agnaf. "Alpha-Synuclein Levels in Blood Plasma From LRRK2 Mutation Carriers." PLoS One.7(12):e5312. December 2012.

Gu, Mingliang, Xiaoqun Dong, Xuezhi Zhang and Wenquan Niu. "The CAG Repeat Polymorphism of Androgen Receptor Gene and Prostate Cancer: A Meta-Analysis." Molecular Biology Reports. 39(3):2615-2624. March 2012.

Gu, Mingliang, Xiaoqun Dong, Li Shi, Lei Shi, Keqin Lin, Xiaoqin Huang and Jeauyon Chu. "Differences in mtDNA Whole Sequence Between Tibetan and Han Populations Suggesting Adaptive Selection to High Altitude." Gene. 496(1):37-44. March 15, 2012.

Gu, Mingliang, Xiaoqun Dong,  Xuezhi Zhang, X. M. Wang, Y. Qi, J Yu and Wenquan Niu. "Strong Association Between Two Polymorphisms on 15q25.1 and Lung Cancer Risk: A Meta-Analysis." PLoS One. 7(6):#e37970. June 6, 2012.

Gunduz, M., U. A. Argikar, A. Kamel, K. Colizza, J. L. Bushee, A. Cirello, F. Lombardo and S. Harriman. "Oxidative Ipso Substitution of 2,4-difluoro-benzylphthalazines: Identification of a Rare Stable Quinone Methide and Subsequent GSH Conjugate." Drug Metabolism and Disposition. 40(11):2074-2080. November 2012

Guo, Shujie, Xiabo Shi, Mion Gao, Hong Kong, Yuqiong Li, Mingliang Gu, Xiaoqun Dong and Wenquan  Niu. "Synergistic Association of PTGS2 and CYP2E1 Genetic Polymorphisms With Lind Cancer Risk in Northeastern Chinese." PloS One. 7(6):#e39814. June 25, 2012.

Harriman, Shawn P.  SEE: Gunduz, M.; Kamel, Amin; Lombardo, Frank.

Harstad, Eric B.  SEE: Liederer, B. M.; Zak, Mark.

Heger, Nicholas E., Susan J. Hall, Moses A. Sandrof, Elizabeth V. McDonnell, Janan B. Hensley, Eerin N. McDowell, Kayla A. Martin, Kevin W. Gado, Kamin J. Johnson and Kim Boekelheide. "Human Fetal Testus Xenografts Are Resistant to Phthalate-Induced Endocrine Disruption." Environmental Health Perspectives. 120(8):1137-1143. August 2012.

Henry, G. E., T. Yuan, M. Edmonds, L. Li and N. P. Seeram. "Antioxidant and Alpha-Glucosidase Inhibiting Activity (Abstract)." Planta Medica. 78(11):1228. August 2012.

Hingorani, L., N. P. Seeram and B. Ebersole. "High Throughput Screening for Botanical Abstracts (Abstract)." Planta Medica. 78(11):1131. August 2012.

Jain, Anshu, Lifang Xu, Vaidyananathan, Vilpin Jain and Bongsup P. Cho. "Fluorescence Probing of the 5' vs 3' Flanking Cytosine in Arylamine Induced-2 Bulge Structures (Abstract)." Abstracts of the American Chemical Society.  224:TOXI-92. 2012.

Jain, Vilpin, Benjamin Hilton, Satyakam Patnaik, Yue Zhou, M. Paul Chiarelli and Bongsup P. Cho. "Conformational and Thermodynamic Properties Modulate the Nucleotide Excision Repair of 2-Aninofluorene and 2-Acetylamenofluorene dG Adducts in the Narl Sequences." Nucleic Acids Research. 40(9):2939-3951. May 1, 2012.

Jain, Vilpin, Benjamin Hilton, Yue Zou and Bongsup P. Cho. "Nucleotide Excision Repair of Cluster Acetyla,nofluorene DNA Lesions in E. Coli: Sequence and Thermodynamic Effec ts (Abstract)." Abstracts of the American Chemical Society. 2012. TOXI-86.

Jay, Gregory D.  SEE also: Akelman, Matthew R.; Drewnaik, Elizabeth I.; Elsaid, K. A.; Kobayashi, L.;  Valente, J. H.; Waller, Kimberly A.; Zhao, C.

Jay, Gregory D., Khalen A. Elsaid, Scott C. Anderson, Liang Zhang, Erin Teeple, Kimberly  Waller and Bradon C. Fleming. "Prevention of Cartilege Degeneration and Gait Asymmetry by Lubricin Tribosupplementation in the Rat Following ACL Transection." Arthritis and Rheumatism. 64(4):1162-1171. April 2012.

Jean-Gilles, Dinorah, Liya Li, Hang Ma, Tao Yuan, Clinton O. Chichester III and Navindra P. Seeram. "Anti-Inflammation Efforts of Polyphenolic-Enriched Red Raspberry Extract in Antigen-Induced Arthritis Rat Models." Journal of Agricultural and Food Chemistry. 60(23):5756-5762. June 13, 2012.

Jin, Yuyan, Robert Bies, Marc R. Gastonguay, Norman Stockbridge, Jogarao Gobburu and Rajanikanth Madabushi. "Misclassification and Discordance of Measured Blood Pressure From Patient's True Blood Pressure in Current Clinical Practice: A Clinical Trial Simulation Case Study." Journal of Pharmacokinetics and Pharmacodynamics. 39(3):283-294. June 2012.

Johnson, Kamim J., Nicholas E. Heger and Kim Boekelheide. "Of Mice and Men (and Rats): Phthalate-Induced Fetal Testis Endocrine Disruption Is Species-Dependent." Toxicologic Sciences. 129(2):235-248. October 2012.

Jones, Hannah M., Hugh A. Barton, Yurong Lai, Yi-An Bi, Emi Kimoto, Sara Kempshall, Sonya C. Tate, Ayman El-Khattan, J. Brian Houston, Aleksandr Galetin and Katherine S. Fenner. "Mechanistic Pharmacokinetic Modelling for the Prediction of Transporter-Mediated Disposition in Human From Sandwich Culture Human Hepatocyte Data." Drug Metabolism and  Disposition. 40(5):1085-1092. June 2012.

Kalgutkar, A. S.  SEE also: Bhattachaya, Samit K.;  Leoung, Louis; Orr, Suvi T. M.; Rand, Arthur C.; Ryder, Tim; Smith, Dennis A.; Wolford, Angela.

Kalgutkar, A. S. and D. K. Dalvie. "Drug Discovery for a New Generation of Covalent Drugs (Correction)." Expert Opinion on Drug Discovery. 7(9):861. September 2012.

Kalgutkar, Amat S. Reactive Drug Metabolites. Wiley-VCH. (Methods and Principles in Medicinal Chemistry v.55) 2012. 385p.

Kamel, Amin, Kevin Colizza, Mithat Gunduz, Shawn Harriman and R. Scott Obach. "In Vitro-In Vivo Correlation for Intrinsic Clearance for CP-409,092 and Sumatriptan: A Case Study to Preduct the In Vivo Clearance for Compounds Metabolized by Monoamine Oxidase." Xenobiotica. 42(4):355-362. April 2012.

Kamel, A., K. Colizza and R. S. Obach. "In Vitro Metabolism of the 5-Hydroxytryptamine1B Receptor Antsagonist Elzasonan." Xenobiotica. 2012.

Kameshwara Rao, V., Bhupender S. Chhikara, Rakese Tiwari, Amir Nasrolahi Shirazi, Keykavous Parang and Anel Kumar. "One-Pot Regioselective Synthesis of Tetrahydroindazolones and Evaluation of Their Anti-Proliferative and Src Kinase Inhibitory Activities." Bioorganic and Medicinal Chemistry Letters. 22(11):410-414.  January 2012.

Karim, Murni, Chrissy Dae, Wenjing J. Zhao, David Rowley, David Nelson and Marta Gomez-Chiarri. "Role of Antibiotic Production in the Probiotic Activity of Phaeobacter SP S4 Against Bacterial Pathogens of Oysters (Abstract)." Journal of Shellfish Research. 31(1):303-304.. April 2012.

Kay, Jonathan, Brian G. Feagan, Michael S. Guirguis, Edward C. Keystone, Agnes V. Klein, Anthony S. Lubiniecki, Diane R. Mould, Kwasi A. Nyarko, Anthony A. G. Ridgway, Maureen E. Trudeau and Jian Wang. "Health Canada/BIOTECanad Summitt on Regulatory and Clinical Topics Related to Subsequent Entry Biologics (Biosimilars), Ottawa, Canada, 14 May 2012." Biologicals. 40:517-527. November 2012.

Khandri, Vamsikrishna, Nadja B. Cech, Mingyong Xie and Navindra P. Seeram. "Cheminform Abstract: Maplexins, New Alpha-Glucosidase Inhibitors From Red Maple (Acer rubrun) Stems". 143(21   May 22, 2012.

Kimoto, E., K. Yoshida, L. M. Balogh, Y. A. Bi, K. Maeda, A. El-Khattan, Y. Sugiyama and Y. R. Lai. "Characterization of Organic Anion Transporting Polypeptide (OATP) Expression and Its Functional Contributions to the Uptake of Substrates in Human Hepatocycles." Molecular Pharmaceutics. 9(12):35-42. December 2012.

Kimoto, Emi., Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine F. Fenner, Ayman F. El-Kattan and Yurongng Li. "Differential Modulation of Cytochrome P450 Activity and the Effect of 1-aminobenzotriazole on Hepatic Transport in Sandwich Cultured Human Hepatocytes." Drug Metabolism and Disposition. 40(2):407-411. February 2012.

King, Roberta S., Editorial Advisory Board. Drug Metabolism Letters. Vol.6, 2012.

Kislalioglu, M. Serpil.  SEE: Sheth, Pratik.

Kobayashi, Leo, Jennifer A. Dunbar-Viveiros, Jeffrey Devine, Mark S. Jones, Frank L. Overly, John W. Gosbee and Gregory D. Jay. "Pilot-Phase Findings From High-Fidelity In Situ Medical Simulation Investigation of Emergency Department Procedural Sedation." Simulation in Healthcare. 7(2):81-94. April 2012.

Kobayashi, Leo, Lynn A. Sweeney, Anna C. Cousins, Karina S. Bertsch, Fenwick G. Gardiner, Nicole M. Tomaselli, Robert M. Boss III, Frantz J. Gibbs and Gregory D. Jay. "Web Survey and Embedded Intervention on Emergency Department Personnel Perceptions of Role in Patient Experience." European Journal of Emergency Medicine. 19(2):112-116. April 2012.

Kodavanti, Prasada Rao S.  SEE: Royland, Joyce E.; Sueyashi, T.

Koen, Yakov M., Digamta Sama, Todd D. Williams, Nadezhadni A. Galeva, R. Scott Obach and Robert P. Hanzlik. "Identification of Protein Targets of Reactive Metabolites of Tienilic Acid in Human Hepatocytes." Chemical Research in Toxicology. 25(5):1145-1154. May 21, 2012.

Kovoor, Abraham.  SEE:Ahmed, M. S.;   Celver, Jeremy.

Kumar, Anil, Manoj Kumar Muthyala, Sunita Choudhary, Rakesh K. Tiwari and Keykavous Parang. "Ionic Liquid as Soluble Support for Synthesis of 1,2,3-Thiadiazoles and 1,2,3-Selenadiazoles." Journal of Organic Chemistry. 77(20):9391-9396. October 19, 2012.

Lai, Y., M. Varma, B. Feng, J. C. Stephens, E. Kimoto, A. El-Khattan, K. Ichikawa, H. Kikkawaa, C. Ono, A. Suzuki, M. Suzuki, Y. Yanamoto and L. Tremaine. "Impact of Drug Transporter on Pharmacogenomics on Pharmacokinetic and Pharmacodynamic Variability-Consideratioons for Drug Development." Expert Opinions on Drug Metabolism and Toxicology. 8(6):722-743. June 2012.

Laplante, Kerry L. Simon A. Sarkesian, Suzanne Woodmansee, David C. Rowley and Navindra P. Seeram. "Effects of Cranberry Extracts on Growth and Biofilm Production of Esherichia coli and Stapholococcus Species." Phytotherapy Research. 26(9):1371-1374. September 2012.

Leung, Louis, Anit S. Kalgutkar and R. Scott Obach. "Metabolic Activation in Drug-Induced Liver Injury." Drug Metabolism Reviews. 44(1):18-33. February 2012.

Lewis, Nerissa A., Fange Liu, Luke Seymour, Anthony Magnusen, Travis R. Erves, Jesse Foyle Arca, Floyd A. Beckford, Ramaiyer Venkatramen, Aantonio Gonzalez-Sarrias, F. R. Fronczek, Don G,. Van Derveeer, Navindra P. Seeram, Aimin Liu, William L. Jarrett and Alvin A. Holder. "Synthesis, Characterisation, and Preliminary In Vitro Studies of Vanadium(IV) Complexes With a Schiff Base and Thiosemicarbazones as Mixed Ligands." European Journal of Inorganic Chemistry. 4:664-677. February 2012.

Li, Liya and Navindra P. Seeram. "Appendix C."  IN:  Patil, Bhimangoulda S., Guddadarangavvanahally K. Jayaprakasha, Kotamballi N. Chidambara Murthy and Navindra P. Seeram, Editors. Emerging Trends in Dietary Components for Preventing and Combating Diseases. American Chemical Society. (ACS Symposium v.10093) 2012.  p.587-589.

Li, Liya and Navindra P. Seeram. "Chemical Composition and Biological Effects for Maple Syrup."  IN: Patil, Bhimangoulda S., Guddadarangavvanahally K. Jayaprakasha, Kotamballi N. Chidambara Murthy and Navindra P. Seeram, Editors. Emerging Trends in Dietary Components for Preventing and Combating Diseases. American Chemical Society. (ACS Symposium v.10093) 2012.  p.323-333.

Li, Y., Y. T. Hsai, C. W. Hsu, D. Erol, J. Yang, W. H. Wu, R. J. Davis, D. Egli and S. H. Tsang. Long-Term Safety and Efficacy of Human-Induced Pluriptent Stem Call iPS) Grafts in a Preclinical Model of Retinitis Pigmentosa." Molecular Medicine. 18:1312-1319. December 6, 2012.

Liederer, B. M., X. R. Liu, L. M. Berezhkovskiy, G. Cain, X. Ding, J. Gaudinp, R. Kaus, E. G. Plise, D. P. Sutherline and E. B. Harstad. "Preclinical Steroselective Disposition and Toxicokinetics of Two Novel MET Inhibitors." Xenobiotica. 42(5):456-465. May 2012.

Loblaw, Andrew, Alexis A. Prestrud, Mark R. Somerfield, Thomas K. Oliver, Melissa C. Brouwers, Robert K. Nam, Gary H. Lyman and Ethan Basch. "American  Society of Clinical Oncology Clinical Practice Guidelines: Formal Systematic Review-Based Consensus Methodology." Journal of Clinical Oncology. 30(25):3136-3140. September 1, 2012.

Logothestis, Christopher J., Ethan Basch, Arturo Malino, Karim Fizazi, Scott A. North, Kim N. Chi, Robert J. Jones, Oscan B. Goodman, Paul N. Mainwaring, Cora N. Sternberg, Eleni Efstathiou, Dennis D. Gagnon, Margaret Rothman, Yanni Hao, Cameron S. Liu, Thian S. Kheoh, Christopher N. Haqq, Howard I. Scher and Johanns de Bona. "Effect of Abiratrone Acetate and Prednisone Compared With Placebo and Prednisone on Pain Control and Skeletal-Related Events in Patients With Metastatic Castration-Resistant Prostate Cancer: Exploratory Analysis if Data From the COU-AA-301 Randomised Trial."  Lancet Oncology. 13(12):1210-1217. December 2012.

Lombardo, Frank, N. J. Waters, Upendra A. Ragikar, Michelle K. Dennehy, Jeremy Zhan, M. Gunduz, Shawn P. Harriman, Giuliano Berelini, Ivan Leric Ragilic and R. Scott Obach. "Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Viro Anima; Pharmacokinetic Data, Part 1: Volume of Distribution at Steady State." Journal of Clinical Pharmacology. 2012.

Lombardo, Frank, Nigel J. Waters, Upendra A. Ragikar, Michelle K. Dennehy, Jeremy Zhan, Mithat Gunduz, Shawn P. Harriman, Guiliano Berelini, Ivana Liric Ragilic and R. Scott Obach. "Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Viro Anima; Pharmacokinetic Data, Part 2: Clearance." Journal of Clinical Pharmacology. 2012.

Longato, Lisa, Kelsey Ripp, Mashiko Setshedi, Miroslav Dostalik, Fatemeh Akhlaghi,  Mark Branda, Jack R. Wands and Suzanne M. de la Monte. "Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease." Oxidative Medicine and Cellular Longevity. 2012:479348.   17p.

Lu, Wei.   SEE also: Ramadan, Samy.

Lu, Wei. "Adsorptive-Mediated Brain Delivery Systems." Current Pharmaceutical Biotechnology. 13(12):2340-2348. September 2012.

Lu, Wei. "Nanoparticles for Cancer Treatment."  Medicine and Health, Rhode Island. 95(9):294-295. September 2012.

Ma, Hang, Liangran Guo, Maxwell Edmonds, Wei Lu and Navindra P. Seeram. "Inhibitory Effects of a Solid Lipid Circumin Particle Formulation (Abstract)." Abstracts of the American Chemical Society. 2012.  AGFD-54.

Ma, H., L. Guo, T. Yuan, M. Edmonds, L. Li and N. P. Seeram. "Inhibitory Effects of Sumac (Rhus SPP.) Fruit Extracts and Pentagalloyl Glucose on Mushroom Tyrosinase Enzyme (Abstract)." Planta Medica. 78(11):1230. August 2012.

Ma, Hang, Tao Yuan, Antonio Gonzalez-Sarrias, Liya Lui, Maxwell E. Edmonds and Navindra P. Seeram. "New Galloyl Derivative From Winged Sumac (Rhus copallinum) Fruit." Natural Products Communications. 7(1):45-46. January 2012.

Macwan, Joyce S., Ileana A. Ionita and Fatemeh Akhlaghi. "A Simple Assay for the Simultaneous Determination of Rosuvastatin Acid, Rosuvantatin-5S-Lactone, and N-Desmethyl Rosuvastatin in Human Plasma Using Liquid Chromotography-Tandem Mass Spectrometry (LC-MS/MS)." Analytical and Bioanalytical Chemistry. 402(3):1217-1227. January  2012.

Maloney, B., K. Sambamurti, N. Zawia and D. K. Lahiri. "Applying Epigenetics to Alzheimer's Disease Via the Latent Early-Life Associated Regulation (LEARn) Model." Current Alzheimer's Disease. 9(5):589-599. June 2012.

Mao, Zhao, Xiaofei Luan, Gang Cao, Wei Lu, Jing Xiong, Gang Hu, Ruini Chen,  Rui Ning, Wei Sheng, Jian Yang and Bingfang Yan. "DEC1 Binding to the Proximal Promoter of CYP3A4 Ascribes to the Downregulation of CYP3A4 Expression by IL-6 in Primary Human Hepatocyctes." Biochemical Pharmacology. 84(5):701-711. September 2012.

Mehroto, Shailly, Jeffrey Florian Jr. and Jogarao Gobburo. "Don't Get Boxed IN: Commentary on the Visual Inspection Practices to Assess Exposure-Response Relationships From Binary Clinical Variables." Journal of Clinical Pharmacology. 52(12):1912-1917. December 2012.

Mochalkin, Igor.  SEE: Warmus, Joseph S.

Moffitt, Jeffrey R.  SEE Also: Chistol, G.

Moffitt, Jeffrey R., Jeffrey B. Lee and Philippe Cluzel. "The Single-Cell Chemostat: An Agarose-Based Microfluidic Device for High-Throughput, Single- Cell Studies of Bacteria and Bacterial Communities." Lab Chip. 12(8):1487-1494. April 21, 2012.

More, Vijay R., Xia Wan, Paul E. Thomas, Lauren M. Aleksunes and Angela L. Slitt. "Severe Diabetes and Leptip Resistance Cause Differential Hepatic and Renal Transporter Expression in Mice." Comparative Hepatology. 11(1):1. April 23, 2012.

Mould, Diane R.  SEE: Kay, Jonathan; Ordas, Ingrid; Parikh, Asit; Smith, William B.

Musharraf, Syd. Ghulam Muhammad Shoaib, Amma Jabtar Siddiqui, Muhammad Najan-ul-Haq and Aftab Ahmed. "Qualitative Analysis of Some Important Metals and Metallids in Tobacco Products by Inductively Coupled Plasma-Mass Spectroscopy (ICP-MS) Chemistry." Chemistry Central Journal. 6:#56. June 18, 2012.

Muthyala, Manoj Kumar,  Bhupendwer S. Chhikara, Keykavous Parang and Anil Kumar. "Ionic Liquid Supported Synthesis of Sulfonamides and Carboxamides." ACS Combinatorial Science. 14(1):60-65. January 9, 2012.

Muthyala, Manoj Kumar,  Bhupendwer S. Chhikara, Keykavous Parang and Anil Kumar. "Ionic Liquid-Supported 1,5,7-Triazabicyclo [4.40] dec-5-ene-An Efficient and Recylable Organocatalyst for Michael Addition to Alpha, Beta-Unsaturated Ketones." Canadian Journal of Chemistry. 90(3):290-297. March 9, 2012.

Nahhas, A., R. K. Tiwari and K. Parang. "Application of Self-Assembled Amphipile Peptides Containing Tryptophon, Argines, and Glutami Acid for Generation of Gold Nanoparticles (Abstract)." Abstracts of Papers of the American Chemical Society. MARM 264. 2012.

Nahhas, Alaa,  Rakesh K. Tiwari, Deendayal Mandal and Keykavous Parang. "Cyclic and Linear Homochiral Decapeptides Containing Tryptopjem and Argininellysine Residues as Src Inhibitors (Abstract)." Abstracts of Papers of the American Chemical Society. MARM 316. 2012.

Nahhas, Alaa F., Rakesh K. Tiwari and K. Parang. "Peptides Containing Tryptophan and Argininer as Sre Kinase Inhibitors (Abstract)." Abstracts of the American Chemical Society. 2012.  MEDI-54.

Nahar, Pragati, Maureen Driscoll, Angela Slitt and Navindra P. Seeram. "Anti-Inflammatory Effects of a Solid Lipid Circumin Particle Formulation (Abstract)." Abstracts of the American Chemical Society. 2012.   AGDF-154.

Nam, Robert K., Thomas K. Oliver, Andrew J. Vickers, Ian Thompson, Philip W. Kantoff, Howard L. Parnes, Andrew Loblaw, Bruce J. Roth, June Williams, Sarah Temin and Ethan Basch. Prostate-Specific Antigen Test for Prostate Cancer Screening: American Society for Oncology Provisional Clinical Opinion." Journal of Oncology Practice. 8(5):315-317. September 2012.

Nasrolah Shirazi, Amar, Rakesh Tiwari, Guofeng Ye and Keykavous Parang. "Amphiphile Cyclic Peptide [WR]H as an Efficient Transporter of Negatively Charged Phosphopeptides (Abstract)." Abstracts of Papers of the American Chemical Society. MARM 343. 2012.

Nasrolah Shirazi, Amar, Rakesh Tiwari, Bhupender S. Chhikari, Deendayai Mandel and Keykavous Parang. "Synthesis and Evaluation of Cell-Penetrating Peptide-Doxoprubucin Conjugates (Abstract)." Abstracts of the American Chemical Society. 2012.  MEDI-66.

Needham, Thomas E.  SEE: Patel, Jagdishwar R.

Ng, K. W., N. Venketasubramanian, L. L. Yeo, A. Ahmed, R. C. Seet, H. L. Teoh, B. P. Chan and V. K. Sharma. "Usefulness of CT Angiography for Therapeutic Decision Making in Thrombolyzing Intubated Patients With Suspected Basilar Artery Thrombosis." Journal of Neuroimaging. 2012.

Niesen, Daniel, Antonio Gonzalez-Sarrias, Tao Yuan, Genevieve Henry and Navindra P. Seeram. "Bioassay-Guided Isolation of Cytotoxic Isolation of Cytotoxic Constituents From CarretVulpinodea Seeds (Abstract)." Abstracts of the American Chemical Society. 2012.  AGFD-152.

Niesen, D., A. Gonzalez-Sarrias, H. Ma, T. Yuan, G. E. Henry and N. P. Seeram. "Isolation of Cytotoxic Consituents From Carex vulpinoidae Seeds (Abstract)." Planta Medica. 78(11):1213. August 2012.

Obach, Ronald S.  SEE also: Di, L.i Gao, H.; Kamel, A.; Koen, Y. M.; Lombardo, F.; Shaffer, Christopher L.; Sharma, Raman; Strelevitz, Timothy J. Walsky, Robert L.; Yates, Philip.

Obach, R. S. "Heterotropic Effects on Drug-Metabolizing Enzyme Activities: In Vitro Curiosity Emerges as a Clinically Meaningful Phenomenon (Perhaps?)." Clinical Pharmacology & Therapeutics. 91(3):385-387. March.

Obach, R. S., C. Prakash and A. M. Kamel. "Reduction and Methylation of Siprasidone by Glutatathione, Aldehyde Oxidase, and Thiol s-Methyltransferase in Humans: An IN Vitro Study." Xenobiotica. 2012.

Obach, R. S., A. N. Nedderman and D. A. Smith. "A Response to 'Radiolabelled Mass-Balance Extinction and Metabolism Studies in Laboratory Animals: A Commentary on Why They Are Still Necessary'." Xenobiotica. 2012.

Oh, Donghoon, Kerry L. LaPlante, Kayla M. Babcock and Keykavous Parang. "Acylated Cyclic Polyarginine Cell-Penetrating Peptides as Molecular Transporters and Antibacterial Agents (Abstract)." Abstracts of Papers of the American Chemical Society. 2012.  MEDI-356.

Omar, Raed, Liya Li, Tao Yuan and Navindra P. Seeram. "Alpha-Glucoseidase Inhibiting Hydrolyzable Tannins From Eugenia jambalana Seeds." Journal of Natural Products. 75(8):1505-1509. August 2012.

Ordas, Ingrid, Diane R. Mould, Brian G. Eagan and William J. Sandborn. "Anti-TNF Monoclonal Antibodies Inflammatory Bowel Disease Pharmacokinetics-Based Dosing Paradigms." Clinical Pharmacology & Therapeutics. 91(4):634-646. April 2012.

Orr, Suvi T. M., Sharon L. Ripp, T. Eric Ballard, Jaclyn L. Henderson, Dennis O. Scott, R. Scott Obach, Hao Sun and Amit S. Kalgutkar. "Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure-Activity Relationships and Discovery Strategies to Mitigate Drug-Drug Interaction Risks." Journal of Medicinal Chemistry. 55(11):4896-4933. March 12 2012.

O'Dowd, S. T., M. T. Ardah, K. A. Roberts, C. Commins, O. El-Agnaf, J. Svensson, H. Zetterberg, T. Lynch and D. M.  Walsh. "The Determination of Aggregated Tau in Solution and Its Potential as a Tool for the Diagnosis of Tau Particles (Abstract)." European Journal of Neurology. 19(S1)::98. September 2012.

O'Dowd, S. T., M. T. Ardah, P. Johansson, A. Lomakin, G. B. Benedek, K. A. Roberts, G. Cummins, O. M. El-Agnaf, J. Svensson, H. Zetterberg, T. Lynch and D. M. Walsh. "The ELISA-Measured Increase in Cerebrospinal Fluid Tau That Discriminates Alzheinmer's Disease From Other Neurodegenerative Disorders Is Not Attributable to Differential Recognition of Tauy assembly Forms." Journal of Alzheimer's Disease. 2012.

Ozolins, Terence R. S.  SEE: Purssell, Elizabeth.

Pacheco, Sara E., Linette, Moses A. Sandrof, Marguerite M. Vantangol, Susan Hall M. Anderson and Kim Boekelheide. "The Hidden Messages: Sperm RNA Transcripts As Biomarkers of Low Dose Testicular Injury in the Rat (Abstract)." Journal of Andrology. 33(2,S):50. 2012.

Pacheco, Sara E., Linette, Moses A. Sandrof, Marguerite M. Vantangol, Susan Hall M. Anderson and Kim Boekelheide. "The Hidden Messages: Sperm RNA Transcripts As Biomarkers of Low Dose Testicular UInjury in the Rat (Abstract)." Journal of Andrology. 33(2,S):53. 2012.

Pacheco, S. E., L. M. Anderson and K. Boekelheide. "Optimization of a Filter-Lysis Protocol to Purify Rat Testicular Homogenates for Automated Spermatid Counting." Journal of Andrology. 33(5):811-816. September-October  2012.

Pacheco, Sara E., Linette, Moses A. Sandrof, Marguerite M. Vantangol, Susan Hall M. Anderson and Kim Boekelheide. "Sperm RNA Transcripts Are Indicators of Sub-Chronic Low-Dose Testicular Injury in the Fischer 344 Rat." PLoS One. 7(8):e44280. August 31, 2012.

Paleologu, K. E. and O. M. El-Aghnaf. "Alpha-Synuclein Aggregation and Modulating Factors." Subcellular Biochemistry. 65:109-164. 2012.

Paliwal, P. R., A. Ahmed, L. Shen, L. L. Yeo, P. K. Loh, K. W. Ng, V. F. Chong, B. K. Ing, N. Venketasubaramanian, A. K. Sinham, H,. L. Teon, G. Barthla and V. K. Sharma. "Persistence of Hyperdense Middle Cerebral Artery Sign o n Follow-up CT Scan After Intravenous Thrombolysis Is Associated With Poor Outcome."  Cerebrovascular Diseases. 33(5):445-452. March 2012.

Parang, Keykavous.  SEE: Agarwal, H. K.; Chhikara, Bhugender S.; Kameshwara Rao, V.; Kumar, Anil; Muthayala, M. K.; Nahhas, Alaa F.; Oh, Dongheon; Rao, M. S.; Shaikh, I. H.; Sharma, Ramen K.; Shirazi, Amir Nasrolahi; Tiwari, Rakesh K.

Parikh, Asit, Timothy Leach, Tim Wyant, Catherine Scholz, Diane R. Mould, Terry Ponich and Brian G. Feagen. "Velollizunab for the Treatment of Active Ulcerative Colitis: A Randomized Controlled Phase 2 Dose-Ranging Study." Inflammatory Bowel Diseases. 18(8):1470-1479. August 2012.

Patel, Jagdishwar R., Robert A. Carlton, Fu Yuniatine, Thomas E. Needham, Lianming W. and Frederick G. Vogt. "Preparation and Structural Characterization of Amorphous Spray-Dried Dispersions of Tenoxicam With Enhanced Dissolution." Journal of Pharmaceutical Sciences. 101(2):641-663. February 12, 2012.

Patel, Jagdishwar R., Robert A. Carlton, Thomas E. Needham, Clinton Chichester and Frederick G. Vogt. "Preparation, Structural Analysis, and Properties of Tenoxicam Cocrystals." International Journal of Pharmacy. 436(1-2):685-706. July 25, 2012.

Patil, Bhimangoulda S., Guddadarangavvanahally K. Jayaprakasha, Kotamballi N. Chidambara Murthy and Navindra P. Seeram, Editors. Emerging Trends in Dietary Components for Preventing and Combating Diseases. American Chemical Society. (ACS Symposium v.10093) 2012.  607p.

Patil, Bhimangoulda S., Guddadarangavvanahally K. Jayaprakasha, Kotamballi N. Chidambara Murthy and Navindra P. Seeram. "Preface." IN: Patil, Bhimangoulda S., Guddadarangavvanahally K. Jayaprakasha, Kotamballi N. Chidambara Murthy and Navindra P. Seeram, Editors. Emerging Trends in Dietary Components for Preventing and Combating Diseases. American Chemical Society. (ACS Symposium v.10093) 2012.  p.xiii-xiv.

Perlstein, Todd S., Samuel Z. Goldhaber, Kerrie Nelson, Victoria Joshi, T. Vance Morgan, Lawrence J. Leska, Joo-Yeon Lee, Jogarao Gobbaru, David Schoenfeld, Raju Kucherlapati, Mason W. Freeman and Mark A. Creager. "The Creating an Optimal Warfarin Nomagram (CROWN) Study." Thrombosis and  Haemostasis. 107(1):59-68. January 2012.

Pfefferkorn, Jeffrey A., Angel Guzman-Perez, John Litchfield, Robert Aiello, Judith L. Treadway, John Pettersen, Martha L. Minich, Kevin J. Filipski, Christopher S. Jones, Meihua Tu, Gary Aspnes, Hud Risley, Jianwei Bian, Benjamin D. Stevens, Patricia Bourassa, T.heresaD'Aquila, Levenia Baker, Nicole Barucci, Alan S. Robertson, Francis Bourbonais, David R. Derksen, Margit Macdougall, Over Cabrera, Jing Chen, Amanda Lee Lapworth, James A. Landro, William J. Zavadoski, Karen Atkinson, Nahor Haddish-Berhane, Beijing Tan, Lili Yao, Rachel E. Kosa, Menthena; V. Varma, Bo Feng, David B. Duignan, Ayman El-Khattan, Sharad Murdande, Shenping Liu, Mark Ammirati, John Knafels, Paul Dasilva-Jardine, Laurel  Sweet, Spiros Liras and Timothy P. Rolph. "Discovery of (S)-6-(3-cycloentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)Nicotonic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus." Journal of Medicinal Chemistry. 55(3):1318-1333. February 9, 2012.

Purssell, Elizabeth, Andrea D. Weston, Jason J. Thomson, Terri A. Swanson, Nigel A. Brown and Terence R. S. Ozolins. "Noninvasive High-Resolution Ultrasound Reveals Structural and Functional Deficits in Dimethadione-Exposed Fetal Rat Hearts in Utero." Birth Defects Research. Part B. 95:35-46. 2012.

Ramadan, Samy, Liangran Guo, Yajuan Li, Bingfang Yan and Wei Lu. "Hollow Copper Sulfide Nanoparticle Mediated Transdermy Drug Delivery." Small. 8(20):3143-3150. October 22, 2012.

Rand, Arthur C., Siegfried S. F. Leung, Heather Eng, Charles J. Rotter, Raman Sharma, Amit S. Kalagutkar, Yizhong Zhang, Manthena V. Varma, Kathleen A. Farley, Bhagyashree Khunte, CHris Limberakis, David A. Price, Spiros Liras, Alan M. Mathiowetz, Matthew P. Jacobson and R. Scott Lokey. "Optimizing PK Properties of Cyclic Peptides: The Effect of Side Chain Substitutions on Permeability and Clearance." Med ChemCommun. 3:1282-1289. 2012.

Rao, Madharan Sudershan, Bhupender S. Chhikara, Rakesh Tiwari, Anir N. Shirazi, Keykavous Parang and Anil Kumar.  "Microwave-Assisted and Scandium Triflate Catalyzed Synthesis of Tetrahydrobenzo[a]xanthen-11-Ones." Monatsheft fur Chemie. 143(2):263-268. February 2012.

Rao, M. S., B. S. Chhikara, R. Tiwari, A. N. Shirazi, K. Parang and A. Kumar.  "One-Pot Regioselective Synthesis of Tetrohydroindazolones and Evaluation of Their Antiproliferative and Src Kinase Inhibitory Activities." Bioorganic & Medicinal Chemistry Letters. 22(1):410-414. January 1, 2012.

Rodgers, Robert L. "Glucogen and Cyclic Amp: Time to Turn the Page?" Current Diabetes Review. 8(5):362-381. September 2012.

Rogers, H. L., A. Bhattaram, I. Zineh, J. Gobburo, M. Mathis, T. P. Laughren and M. Pacanowski. "CYP2D6 Genotype Information to Guide Pimozide Treatment in Adult abnd Pediatric Patients: Basis for the U,. S. Food and Drug Administration's New Dosin Recommendations." Journal of Clinical Psychiatry. 73(9):1187-1190. September 2012.

Romanus, Dorothy, Hedy L. Kindler, Laura Archer, Ethan Basch, Donna Niedzwiecki, Jane Weeks, Deborah Schag for the Cancer and Leukemia Group. "Does Health-Related Quality of Life Improve for Advanced Pancreatic Cancer Patients Who Respond to Gemcitabine? Analysis of a Randomized Phase III Trial of Cancer and Leukemia Group B (CALGB 80303." Journal of Pain and Symptom Management. 43(2):205-217. February 2012.

Rowley, David C.  SEE: Choi, Hyukjae; Dao, C.; Espinosa, Avelina; Gerwick, L.; Karim, M.;  Laplante, Kerry L.; Sarakisian, S. A.

Royland, Joyce E., Prasada Rao S. Kodavanti, Judith E. Schmid and Robert C. MacPhail. "Toluene Effects on Gene Expression in the Hippocampus of Young Adult, Middle-Age, and Senescent Brown Norway Rats." Toxicological Sciences. 126(1):193-212. March 2012.

Ruegger, Colleen.  SEE: Bose, Sonali; Ghosh, Indrajit.

Ryder, Tim, Gregory S. Walker, Theunis C. Goosen, Roger B. Ruggeri, Edward L. Conn, Benjamin N. Rocke, Kimiberly Lapham, CLaire M. Steppan, David Hepworth and Amit S. Kalgutkar. "Insights Into the Novel Hydrolytic Mechanism of  a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor." Clinical Research in Toxicology. 25(10):2138-2152. October 2012.

Saffarini, C. M., N. E. Heger, H. Yamasaki, T. Liu, S. J. Hall, K. Boekelheide. "Induction and Persistence of Abnormal Testicular Germ Cells Following Gestational Exposure to Di-(n-butyl)Phthalate in p534-Null Mice." Journal of Andrology. 33(3):505-513. May-June 2012.

Sandineni, Anusha and Bongsup P. Cho. "Spectroscopic and Calorimetric Characterization of AAF-Modified DNA Duplexes Containing -1,-2, and -3 Slipped Mutagenic Intermediates (Abstract)." Abstracts of the American Chemical Society. 221:TOXI-89. 2012

Sarkisian, S. A., M. J. Jansesen, H. Matta, G. E. Henry, K. L. Laplante and D. C. Rowley. "Inhibition of Bacterial Growth and Biofilm Production by Constituents From Hypericum spp." Phytotherapy Research. 26(7):1012-1016. July 2012.

Sarodo, A., P. Wang, C. Cote and D. R. Worthen. "Low-Viscosity Hydroxyproplcellulose (HPC) Grades SL and SSL: Versatile Pharmaceutical Polymersd for Dissolution Enhancement, Controlled Release, and Pharmaceutical Procwessing." AAPS PharmSciTech. 1-9, 2012.

Seeram, Navindra P.  SEE also: Apostplidis, Emmanouil; Barbeau, Julie; Beckford, Floyd A.; Bhimanagouda S. Patil; Donepudi, Ajay C.; Gonzalez-Sarrias, Antonio; Henry, G. E.; Hingorani, L.; Lewis, Nerissa A.;  Li, Liya; Ma, Hong; Jean-Gilles, Dinorah; Huang; Khandri, Vamsikrishna; Laplante, Kerry L.; Nahar; Pragati; Niesen, Daniel; Omar, Raed; Patil, Bhimangoulda S.; Wan, Chunpeng; Yuan, Tao.

Seeram, Navindra P. "Emerging Research Supporting the Positive Effects of Berries on Human Health and Disease Prevention." Journal of Agricultural and Food Chemistry. 60(23):5685-5686. June 13, 2012.

Seeram, Navindra P., Liya Li, Genevieve Beland and Julie Barbeau. Novel Phytochemicals From Extracts of Maple Syrups and Maple Trees and Uses Therof. PCT Intl. Appl. WO2012021981 A1 20120223. 2012.

Seeram, Navindra, Jialin Xu, Liya. Lis and Angela Slitt. "Pharmacy Research at URI: Mining Red Maple (Acer rubrum) Trees for Novel Therapeutics to Manage Diabetes." Medicine and Health, Rhode Island. 95(9):283-284. September 2012.

Seifert, Erin L., Annabelle Z. Caron, Katy Morin, Josee Coulombe, Xiao Hontte, Hong He,  Karen Jardine, Danielle Dewarr-Darch, Kim Boekelheide, Mary-Ellen Harper and Michael W. McBurney. "SirT1 Catalytic Activity Is Required for Male Fertility and Metabolic Homeostasis in Mice." FASEB Journal. 26(2):555-566. February 2012.

Shaffer, Christopher L., Renato J. Scailis, Haojing Rong and R. Scott Obach. "Using Simcyp to Project Human Oral Pharmacokinetic Variability in Early Drug Research to Mitigate Mechanism-Based Adverse Events." Biopharmaceutics and Drug Disposition. 33(2):72-84. March 2012.

Shaikh, Imam H., Hitesh K. Agarwal, Keykavous Parang and Reza Mehvar. "Hepatic Immunosuppressive Effects of Systematically Administered Novel Dextran-Methylprednisolone Prodrugs With Peptide Linkes in Rats." Journal of Pharmaceutical Sciences. 101(10):4003-4012. October 2012.

Sharma, Raman, Timothy J. Strevelitz, Hangying Gao, Alan J. Clark, Klass Schildknegty, R. Scott Obach, Sharon L. Ripp, Douglas K. Spracklin, Larry M. Tremaine and Alfen D. Vaz. "Deuterium Isotope Effects on Drug Pharmacokinetis. 1. System-Dependent Effects of Specific Deuteration With Aldehyde Oxidase Cleared Drugs." Drug Metabolism and Disposal. 40(3):625-634. March 2012.

Sharma, Raman K., Sukdev Singh, Rakesh Tiwqari, Deendayal Mandy, Carl E. Olsen, Virinder S. Parma, Keykavous Parang, Ashok K. Prasad. "O-Aryl Alpha, Beta-D-Ribofuranosides Eynthesis & Highly Efficieint Biocatalytic Separation of Aromers and Evaluation of Their Src Kinase Inhibitory Activity." Bioorganic & Medicinal Chemistry. 20(23):6821-6830. 1 December 2012.

Sheth, P., H. Sandhu, D. Singhal, W. Malick, N. Shah and M. S. Kislalioglu. "Nanoparticles in the Pharmaceutical Industry and the Use of Supercritical Fluid Technologies for Nanoparticle Production." Current  Drug Delivery. 9(3):269-284. May 1,  2012.

Slitt, Angela L.  SEE: Chen, Y.; Donepudi, Ajay C.; More, V. R.; Mahar, Pragati; Seeram, Navindra P.; Xu, Jialin.

Smith, Dennis A., Amit S. Kalgutkar , Hon Waterbeemd and Don K. Waker. Pharmacokinetics and Metabolism in Drug Design. 3d ed. Wiley-VCH. 2012. 269p.

Smith, Thomas J., Sarah Temin, Erin R. Alesi, Amy P. Abernathy, Tracy A. Balboni, Ethan M. Basch, Betty R. Ferrell, Matt Loscalzo, Diane E. Meir, Judith A. Paice, Jeffrey M. Peppercorn, Mark Somerfoe;d, Ellen Stovall and Jaime H. Vonroenn. "American Society of Clinical Oncology Provisional Clinical Opinion: The Integration of Palliative Care Into Standard Oncological Care." Journal of Clinical Oncology. 30(8):880-887. March 10, 2012.

Smith, William B., Thomas C. Marbury, Steven F. Komjathy, Mark S. Sumeray, Gregory C. Williams, Ming-Yi Hu and Diane R. Mould. "Pharmacokinetics, Pharmacodynamics, and Safety of Clevidipine After Prolonged Continuous Infusion in Subjects With Mild to Moderate Essential Hypertension." European Journal of Clinical Pharmacology. 2012.

Springer, Cecilia, Edward Dere, Susan J. Hall, Elizabeth V. McDonnell, Simon. Craig Roberts, C. M. Botl, Heather M. Stapelton, Deborah J. Watkins, Michael C. McClean, Thomas F. Webster, Jennifer Schlezinger and Kim Bioejkelheide. "Rodent Thyroid, Liver, and Feta; Testis Toxicity of the Monester Metabolite of Bis-(2 ehyhexyl) Tetrabroenophthalate (TBPH): A Novel Brominated Flame Retardant Present in Indoor Dust." Environmental Health Perspectives. 120(12):1711-1719. December 2012.

Stanislaus, Dinesh, Hakan Andersson, Robert Chapin, Dianne Creasy, Duncan Ferguson, Mary Gilbert, Thomas J. Rosol, Rogely Waite Boyce and Charles E. Wood. "Society of Toxicology Pathology Position Paper: Review Series: Assessment of Circulatory Hormones in Nonclinical Toxicity Studies: General Concepts and Considerations." Toxicologic Pathology. 40:943-950. 2012.

Stephens, Martin L., Craig Barrow, Melvin E. Anderson, Kim Boekelheide, Paul L. Carmichael, Michael P. Holsapple and Mark Lafranconi. "Accelerating the Development of 21st Century Toxicology: Outcome of a Human Toxicology Project Consortium Workshop." Toxicological Sciences. 125(2):327-334. February 2012.

Strelevitz, Timothy J., Christine C. Orozco and R. Scott Obach. "Hydralazine as a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic Clearance." Drug Metabolsim and Disposition. 40(7):1441-1448. July 2012.

Sueyashi, T., H. L. Li, H. B. Wang, R. Moore, P. R. S. Kodavanti, H. J. Lehmler, M. Negishi and L. Birnbaum. "Flame Retardant BDE-47 Effectively Activates the Nuclear Receptor Car in Human Primary Hepatocytes." Drug Metabolism Reviews. 44(S1):111-112. 2012.

Tiwari, R. K. and K. Parang. "Conformationally Contained Peptides as Protein Tyrosine Kinase Inhibitors." Current Pharmaceutical Design. 18(20):2852-2866. July 1, 2012.

Tiwari, Rakesh K., Alex Brown, Amir N. Shirazi, Jarod Bolton, Gongquin Sun and Keykavous Parang. "Dasatinib-Fatty Acid Conjugates: Synthesis and Evaluation of Tyrosine  Kinase Inhibitary and Anticancer Activities (Abstract)." Abstracts of the American Chemical Society. 2012.  MEDI-36.

Tiwari, Rakesh K., Alex Brown, Amir N. Shirazi, Jarod Bolton, Gongquin Sun and Keykavous Parang. "Synthesis and Evaluation of Dasatinib Amino Acid Derivatives for Their Anticancer Kinase Activity Abstract)." Abstracts of the American Chemical Society. 2012.  MEDI-254.

Tsang, S. H., M. L. Woodriff, C. S. Lin, B. D. Jacobson, M. C. Naumann, C. W. Hsu, R. J. Davis, M. C. Cilluffo, J. Chen and G. L. Fain. "Effect of the ILE86TYER Mutation in the y Subunit of cGMP Phospodiesterase (PDE6) on Rod Pbhotorecptor Signaling." Cell Signaling. 24(1):181-188. January 2012.

Tsze, Daniel S., Dale W, Steele, Jason T. Machan, Fatemeh Aklaghi and James G. Linakin. "Intranasal Ketamine for Procedural Sedation in Pediatric Laceration Repair: A Preliminary Report." Pediatric Emergency Care. 28(8):767-800. August 2012.

Ulbright, C., E. Basch, W. Chao, J. Conquer, D. Costa, S. Culwell, K. Flanagan, J. Guilford, P. Hammerness, S. Hashmi, R. SIaac, E. Rusie, J. M. Serrano, C. Ulbricht, M. Vora, R. C. Windsor, M. Woloszyn and S. Zhou. "An Evidence-Based Systematic Review of Vitamin A by the Natural Standard Research Collaboration."  Journal of Dietary Supplements. 9(4):299-416. December 2012.

Vaidyanathan, V. G., Lifang Xu and Bongsup P. Cho. "Binary and Ternary Affinities Between Exonuclease-Deficient Klenow Fragment (Kf-exo-) and Various Arylamine DNA Lesions Characterized by Surface Plasmon Resonance." Chemical Research in Toxicology. 25(8):1568-1570. August 20, 2012.

Vaidyanathan, V. G.. Lifang Xu and B. P. Cho. "Label-Free Analysis of Arylamine Adduct/Polymerase Interactions Using Surface Plasmon Resonance (Abstract)." Abstracts of the American Chemical Society. 221:TOXI-84.  2012.

Vaidyanathan, V. G. and B. P. Cho. "Sequence Effects on Translesion Synthesis of an Amnifluorene-DNA Adduct: Conformational, Thermodynamic, and Primer Extension Kinetic Studies." Biochemistry. 51(9):1983-1995. March 6, 2012.

Valente, Jonathan H., Gregory D. Jay, Scott T. Schmidt, Albert K. Oh, Steven E. Reinert and Christopher P. Zabbo. "Digital Imaging Analysis of Scar Aesthetics." Advances in Skin & Wound Care. 25(3):119-123. March 2012.

Van der Laan, Jan Willem, Robert E. Chapin, Bert Haenen, Abigail C. Jacobs and Albert Piersma. "Testing Strategies for Embryo-Fetal Toxicity of Human Pharmaceutical Animal Modules VS In Vitro Approaches: A Workshop Report." Regulations, Toxicology and  Pharmacology. 63(1):115-123. June 2012.

Varma, Manthena V., Iain Gardner, Stefanus J. Steyn, Paul Nkansah, Charles J. Rotter, Carrie Whitney-Pickett, Hui Zhang, L. Di, Michael Cram, Katherine S. Fenner and Ayman F. El-Khattan. "pH Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BICS and BDDCS) in Early Drug Discovery." Molecular Phamaceutics. 9(5):1199-1212. May 2012.

Varma, Manthena V.S. , George Chang, Yurong Lai, Bo Feng, Ayman F. El-Khattan, John Litchefield and Theunis C. Goosen. "Physiochemical Property Space of Hepato-Billary Transport and Computational Modes for Predicting Rat Billary Extraction." Drug Metabolism and Dispositions. 40(8):1527-1537. 2012.

Velmurugan, K., A. N. Balamurugan, G. Loganathan, A. Ahmed, B. J. Herring and S. Pugaxhenthi. "Antiapoptotic Actions of Extendin-4 Against Hypoxia and Cytokines Are Augmented by CREB." Endocrinology. 2012.

Vickers, Andrew J., Daniel Sjoberg, Ethan Basch, Frank Sculli, Marwan Shourey, Vincent Laudone, Karen Tiuijer, James  Eastham and Peter T. Scardino. "How Do You Know If You Are Any Good? A Surgeon Performance Feedback System for Outcomes of Radical Prostatectomy." European Urology. 61(2):284-289. February 2012.

Waller, K. A., L. X. Zhang, B. C. Fleming and G. D. Jay. "Preventing Friction-Induced Chondrote Apostatsis: Comparison of Human Synoviall Fluid and Hylan G-F 20." Journal of Rheumatology. 39(7):1475-1480. July 2012.

Walsky, Robert L., Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham,. Andre Neghan, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen. "Optimized Assays for Human UDP-Gleuuronosytransferase (UGT- Activities: Altered Alamethicin Concentrations and Utility to Screen for UGT Inhibitor." Drug Metabolism and Disposition. 40(9):1051-1065. May 2012.

Walsky, Robert L., R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kiernan F. Geoghegan, Christopher J. Helal, Grergory S. Walker, Theunis C. Goosen and Michael A. Zientak. "Selective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 Versus CYP3A5 in the Metabolism of Drugs." Drug Metab Dispos. 40(9):1686-1697. September 2012.

Wan, Chunpeng, Tao Yuan, Mingyong Xie and Navindra P. Seeram. "Acer Rubrem phenolics Include A-Type Procyanidins and a Chalcone." Biochemical Systematics and Ecology. 44:1-3. October 2012.

Wan, Chunpeng, Tao Yuan, Amanda L. Cirello and Navindra P. Seeram. "Antioxidant and Alpha-Glucosidase Inhibitopry Phenolics Isolated From Highbush Blueberry Flowers." Food Chemistry. 135(3):1929-1937. December 1, 2012.

Wan, Chunpeng, Tao Yuan, Liya Li, Vamsikrishna Khandi, Nadja B. Cech, Ming Yong Xie and Navindra P. Seeram. "Maplexins, New Alpha-Glucosidase Inhibitors From Red Maple (Acer rubrum) Stems." Bioorganic & Medicinal Chemistry Letters. 22(1):597-600.  January 2012.

Wang, Yaning, P. R. Jadhu, M. Lala and J. V. Gobburu. "Clarification on Precision Criteria to Derive Size When Designing Pediatric Pharmacokinetic Studies." Journal of Clinical Pharmacology. 52(10):1601-1606. October 2012.

Wang, Yaning, J. Y. Lee, T. Michele, B. A. Chowdhory and J. V. Gobburu. "Limitations of Model-Based Dose Selection for Indacaterol in Patients With Chronic Obstructive Pulmonary Disease." International Journal of Clinical Pharmacology and Therapeutics. 50(9):622-630. September 2012.

Warmus, Joseph S., heryl. L. Quinn, Clarke Taykor, Sean T. Murphy, Timothy A. Johnson, Chris Limberakis, Daniel Ortwine, Joel Bronstein, Paul Pagano, John D. Knafels, Sandra. Lightle, Igor Mochalkin, Roger Brideau and Terry Podoll. "Structure Based Design of an In Vivo Active Hydrosamic Acid Inhibitoer of P. aeruginosa LpxC." Bioorganic and Medicinal Chemistry Letters. 22(7):2536-2643. April 1, 2012.

Wert, K. J., J. M. Skele, R. J. Davis, S. H. Tsang and V. B. Mahajan. "Subretinal Injection of Gene Therapy Vectors and Stem Cells in the Perinatal Mouse Eye." Journal of Visualized Experiments. November 2012.

Wolford, Angela, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar. "Immune-Mediated Agranolocytosis Casued by the Cocaine Adulterant Lemamisole: A Case for Reactive Metabolite(s) Involvement." Drug Metabalism and Disposition. 40(6):1067-1075. 2012.

Worthen, David R.  SEE: Conca, Addison J.; Sarodo, A.

Xiao, Da, Yi-Tzai Chen, Dongfang Yang and Bingfang Yan. "Age-Related Inducibility of Carboxylesyterases by the Antiepileptic Agent Phenobarbital and Implications in Drug Metabolism and Lipid Accumulation." Biochemical Pharmacology. 84(2):232-239. July 2012.

Xu, Jialin, Supria R. Kulkarni, Ajay C. Donepudi, Vijay R. More and Angela L. Slitt. "Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation in Adipose Tissue, and Increases Hepatic Steatosis in Leptin-Deficient Mice." Diabetes. 61(12):3208-3218. December  2012.

Xu, Jialin, Supria R. Kulkarni, Liya Li and Angela L. Slitt. "UDP-Glucuronosltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis." Drug Metabolism ands Disposition. 40(2):259-266. February 2012.

Xu, Lifang, V. G. Vaidyanathan and B. P. Cho. "Systematic Spectroscopic and Thermodynamic Innvestigation of Slippage Mediated Frameshift Metagenesis  (Abstract)." Abstracts of the American Chemical Society. 221:TOXI-97. 2012.

Yan, Bingfang.  SEE also: Chen, Y.; Chen, Yi-Tzai; Xhao, Mao; Xiao, Da; Yang, Dingfang; Ramadon; S.; Zhao, Mao.

Yan, Bingfang.  "Carboxylesterase."  IN: Encyclopedia of Drug Metabolism and Interactions, Edited by Alexander V. Rodrigues and Michael A. Sinz. 2012.  1:423-456.

Yan, Bingfang.  "Hydrolytic Enzymes."  IN: Metabolism of Drugs and Other Xenobiotics, Edited by Pavel Anzenbacher and Ulrich M. Zanger. 2012.  p.147-164. 2012.

Yang, Dingfang, Jian Yang, Deshi Shi, D. Xiao, Yi-Tzai Chen,  Chris Black, Ruitang Deng and Bingyang Yan. "Hypolipidemic Agent Z-Guggulsterone: Metabolism Interplays With Induction oif Carboxylesterase and Bile Salt Export Pump." Journal of Lipid Research. 53(3):529-539. March 2012.

Yang, J., M. C. Naumann, Y. T. Tsai, J. Tosi, D. Erol, C. S. Lin, R. J. Davis and S. H. Tsang. "Long-Term Safety and Efficacy of Human-Induced Pluripoint Stem Cell (iPS) Grafts in a Preclinical Model of Retinitis Pigmentosa." PLoS One. 7(8):e43889. 2012.

Yates, Philip, Heather Eng, Li Di and R. Scott Obach. "Statistical Methods for Analysis of Time-Dependent Inhibition of Cytochrome P450 Enzymes." Drug Metabolism and Disposition. 40:2289-2296. December 2012.2012.

Yuan, Tao, Yuanqing Ding, Chunpeng Wan, Liya Li, Jialin Xu, Ke Liu, Angela Slitt, Daneel Ferrera, Ikhlas A. Khan and Navindra P. Seeram. "Antidiabetic Ellagitannins From Pomegranate Flowers: Inibition of Alpha-Glucosidase and Lipogenic Gene Expression." Organic Letters. 14(20):5358-5361. October 2012.

Yuan, Tao, Chunpeng Wan, Ke Liu and Navindra P. Seeram. "New Maplexins-F-1 and Phenolic Glycosides From Red Maple (Acer rubrum) Bark." Tetrahedron. 68(4):959-964. 28 January  2012.

Yuan, T., D. Ferreira and N. P. Seeram. "Punicatannins A and B: Alpha-Glucosidase Inhibitory Ellagitannins From Pom,egranate (Punica garnatum) Flowers (Abstract)." Planta Medica. 78(11):1179. August 2012.

Zak, Mark, Rohan Mendonca, Merceddes Balazs, Kathy Barrett, Philippe Bergeron, Wade S. Blair, Christian Chang, Gauri Deshmukh, Jason DeVoss, Peter S. Gragovich, Charles Eigenbrot, Nico Ghilardi, Paul Gibbons, Stefan Gradl, Chris Hamman, Emily J. Hanan, Eric Harstad, Paul R. Hewitt, Christopher A. Hurley, Tian Jin, Adam Johnson, Tony Johnson, Jane R. Kenny, Michael F. T. Koehler, Pawan Bir Kohli, Janusz J. Kulagowski, Sharada Labadie, Jiangpeng Liao, Marya Limimatta, Zonghua Lin, Patrick Lupardus, Robert  J. Maxey, Jeremy M. Murray, Rebecca Pulk, Madeleine Rodriguez, Scott Savage, Steven Shia, Micah Steffek, Savita Ubhayakar, Mark Ultisch, Anne van Abbema, Stuart I. Ward, Ling Xiao and Yisong Xiao. "Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors With Selectivity Over JAK2." Journal of Medicinal Chemistry. 55(13):6176-6193. July 12, 2012.

Zaroogian, Gerald E., Ruth E. Gutjahr-Gobell, Doranner B. Horowitz, Saro Jayaraman, Mark Cantwell, Clinton O. Chichester and L. J. Mills. "An Injectable, Slow-Release Implantation Method fopr Exposing Fish to Chemicals Over a Period of Weeks." North American Journal of Aquaculture. 74(4):515-521. 2012.

Zawia, Nasser H.  SEE also: Adwan, Lina;  Alashwal, Hany; Bihaqi, S. W.; Dosunmu, Remi.

Zawia, Nasser H. and D. K. Lahiri. "Editorial: Epigentics: A Paradigm Shift in Understanding Alzheimer's Disease." Current Alzheimer Disease. 9(5):525-526. June 2012.

Zhao, Chunfend Yu-Long Sun, Gregory D. Jay, Steven L. Moran, Kai-Nan and Peter C. Amadio. "Surface Modification Counteracts Adverse Effects Associated With Immunobilization After Flavor Tendon Repair." Journal of Orthopaedic Research. 30(2):1940-1944. December 2012.

Zhao, Mao, Luan Xiaofei, Gang Cao , Wei Lui, Jing Xiong , Gana Hu, Rui Chen Ning Ruini, Wei Shang , Jian Yang and Bingfang Yan. "DEC1 Binding to the Proximal Promoter of CYP3A4 Ascribes to the Downregulation of CYP3A4 Expression by IL.6."  Biochemical Pharmacology. 84(5):701-711. 15 September 2012.

Zijlstra, Albert A. and Richard J. Davis. "Retrospective: Sir Bernard Lovell (1913-2012)." Science. 337(6100):1307. September 14, 2012.

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