Roberta S. King, Ph.D.
Associate Professor of  Toxicology and Medicinal Chemistry
rking@uri.edu

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Education

• Ph.D., University of Iowa, 1995, 
  Medicinal and Natural Products Chemistry
• B.S., University of Kansas, 1989,
  Chemistry

Research Interests:

Biotransformation and Chemical Toxicology

• Sulfotransferase biochemistry and physiological effects of inhibition.
• Mechanisms causing inter-individual variation in metabolism.
• Biotransformation of heterocyclic amine carcinogens in animal models and human tissues.

Publications:

Yalcin EB, Struzik SM, *King RS (2008) Allosteric modulation of SULT2A1 by celecoxib and nimesulide: Computational analyses. Drug Metabolism Letters, 2(3):198-204.
(http://www.ingentaconnect.com/content/ben/dml/2008/00000002/00000003/art00010)

Yuan Z, Jha G, McGregor M, and *King RS (2007) Metabolites of the carcinogen 2-amino-alpha-carboline formed in male Sprague-Dawley rats in vivo, and in rat hepatocyte and human HepG2 cell incubates. Chemical Research in Toxicology, 20:497-503. PMID: 17291013. (http://www.ncbi.nlm.nih.gov/sites/entrez/17291013)

*King RS, Ghosh AA, Wu J (2006) Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents. Current Drug Metabolism, 7(7):745-753. PMID: 17073578. (http://www.ncbi.nlm.nih.gov/sites/entrez/17073578)

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