David C. Rowley, Ph.D.
Associate Professor of Pharmacognosy
drowley@uri.edu

Education

• Ph.D., University of California, San Diego, 2001
• B.S., The Pennsylvania State University, 1990

Research Interests:

• Bioactive secondary metabolites produced by marine microorganisms.

Dr Rowley, Talking about his research into microbial resistance Video Clip Text Script

Publications:

• Rowley DC, Kelly S, Jensen P, Fenical W. Synthesis and structure–activity relationships of the halovirs, antiviral natural products from a marine-derived fungus.  Bioorg. Med. Chem. 2004, 12: 4929-4936.
  

• Rowley DC, Kelly S, Kauffman C, Jensen P, Fenical W. Halovirs A-E, new antiviral agents from a marine-derived fungus of the genus Scytalidium. Bioorg. Med. Chem. 2003, 11: 4263-4274.
  

• Spyere A, Rowley DC, Jensen P, Fenical W. New neoverrucosane diterpenoids produced by the marine gliding bacterium Saprospira grandis. J. Nat. Prod. 2003, 66: 818-822.
  

• Rowley DC, Hansen M, Rhodes D, Bushman F, Fenical W. Thalassiolins A-C: new marine-derived inhibitors of HIV cDNA Integrase. Bioorg. Med. Chem. 2002; 10:3619-3625.
  

• Hwang Y, Rowley DC, Rhodes D, Gertsch J, Fenical W, Bushman F. Mechanism of inhibition of a poxvirus topoisomerase by the marine natural product sansalvamide A. Molecular Pharm. 1999; 55:1049-1053.

Patents:

• Fenical, W., Jensen, P.R., and Rowley, D.C., "Halovir, an antiviral marine natural product and derivatives thereof." Application for United States Letters Patent, filed December 1998.
• Semple, J.E., Ardecky, R.J., Nutt, R.F., Ripka, W.C., Rowley, D.C, Lim-Wilby, M.S.L., and Brunck, T.K. United States Letter Patent Number 5,703,208.

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