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Fatemeh
Akhlaghi, Pharm. D., Ph.D.
Associate Professor of Pharmacokinetics
fatemeh@uri.edu
Click here for information about Dr. Akhlaghi's lab
Education:
- Ph.D., University of Sydney, Australia, 1996
- Pharm.D., University of Mashhad, Iran, 1990
Experience:
-
Associate Professor
with Tenure, College of Pharmacy, University of Rhode Island, USA;
2006-current
-
Assistant Professor,
College of Pharmacy, University of Rhode Island, USA; 2001-2005
-
Senior Clinical
Scientist, Pharmacology Clinical Research Unit, Addenbrooke's and
Papworth Hospitals, University of Cambridge, United Kingdom; 1998-2000
-
Postdoctoral Research
Associate, Faculty of Pharmacy, University of Sydney, Australia;
1996-1998
Research Interests:
-
Immunosuppressive
agents PK/PD following organ transplantation
-
Therapeutic drug
monitoring
- Drug
disposition and effect in diabetes mellitus
Publications:
Rosenbaum SE, Baheti G, Trull AK,
Akhlaghi F. Population pharmacokinetics of cyclosporine in
cardiopulmonary transplant recipients. Ther Drug Monit 2005;
27:116-122.
Soman RS, Zahir H, Akhlaghi F.
Development and validation of an HPLC-UV method for determination of
iohexol in human plasma. J Chromatogr B Analyt Technol Biomed Life
Sci 2005; 816:339-343.
Zahir H, McLachlan AJ, Nelson A,
McCaughan G, Gleeson M, Akhlaghi F. Population pharmacokinetic
estimation of tacrolimus apparent clearance in adult liver transplant
recipients. Ther Drug Monit 2005; 27:422-430.
Akhlaghi F,
Gonzalez L, Trull AK. Association between cyclosporine concentrations at
2 hours post-dose and clinical outcomes in de novo lung transplant
recipients. J Heart Lung Transplant 2005; 24:2120-2128.
Akhlaghi F,
Patel CG, Zuniga XP, Halilovic J, Preis IS, Gohh RY. Pharmacokinetics of
mycophenolic acid and metabolites in diabetic kidney transplant
recipients. Ther Drug Monit 2006; 28:95-101.
Mendonza AE, Gohh RY, Akhlaghi F.
Analysis of mycophenolic acid in saliva using liquid chromatography
tandem mass spectrometry. Ther Drug Monit 2006; 28:402-406.
Shi D, Yang J, Yang D, LeCluyse EL,
Black C, You L, Akhlaghi, F, Yan B. Anti-influenza prodrug
oseltamivir is activated by carboxylesterase human carboxylesterase 1,
and the activation is inhibited by antiplatelet agent clopidogrel. J
Pharmacol Exp Ther 2006; 319:1477-1484.
Zahir H, Keogh A, Akhlaghi F.
Apparent clearance of sirolimus in heart transplant recipients: impact
of primary diagnosis and serum lipids. Ther Drug Monit 2006;
28:818-826.
Mendonza AE, Zahir H, Gohh RY,
Akhlaghi F. Tacrolimus in diabetic kidney transplant recipients:
pharmacokinetics and application of a limited sampling strategy. Ther
Drug Monit 2007; 29:391-398.
Patel CG, Richman K, Yang D, Yan B, Gohh
RY, Akhlaghi F. Effect of diabetes on mycophenolic acid
concentration and inosine monophosphate dehydrogenase activity in kidney
transplant recipients. Ther Drug Monit
2007; 29:735-742.
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