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Dr. Chichester's video

Department Chair
Clinton O. Chichester, Ph.D.
Professor of Pharmacology and Toxicology
chichester@uri.edu

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Research Interests:

• Connective tissue pharmacology
• Collagen degradation in osteoarthritis
• Alterations in drug metabolism in septic shock

Aftab Ahmed, Ph.D.
Research Assistant Professor
aahmed@uri.edu

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Research Interests:

• Protein purification and characterization including amino acid sequencing and mass spectrometry
   

Fatemeh Akhlaghi, Pharm. D., Ph.D.
Associate Professor of Pharmacokinetics
fatemeh@uri.edu

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Research Interests:

• Immunosuppressive agents PK/PD following organ transplantation
• Therapeutic drug monitoring
• Drug disposition and effect in diabetes mellitus

Bongsup P. Cho, Ph.D.
Professor of Medicinal Chemistry
bcho@uri.edu

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Research Interests:

• Chemical carcinogenesis of polyarenes and their amino and nitro derivatives with   major emphasis on the molecular consequence of adduct formation in DNA
• Structural  biology of carcinogen (drug)-macromolecular interactions, mechanisms of mutation,  DNA adduct chemistry.

Ruitang Deng, Ph.D.
Assistant Professor
dengr@mail.uri.edu

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Research Interests:

• Bile acids and cholesterol homeostasis, regulation and related diseases
• Drug transporters and toxicology
• Biological and pharmaceutical therapy development

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Dr. King's video

Roberta S. King, Ph.D.
Associate Professor of  Toxicology and Medicinal Chemistry
rking@uri.edu

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Research Interests:
Biotransformation and Chemical Toxicology

• Sulfotransferase biochemistry and physiological effects of inhibition.
• Mechanisms causing inter-individual variation in metabolism.
• Biotransformation of heterocyclic amine carcinogens in animal models and human tissues.
   

M. Serpil Kislalioglu, Ph.D.
Professor of Pharmaceutics
skis@uri.edu

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Research Interests:

• Characterization of oils, waxes and polymers
• Formulation, characterization and stability of regular and
  controlled-delivery systems
• Topical delivery
• Quantification of sensory attributes of topical products and regulatory aspects of cosmetic usage.

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Research Interests:

• Molecular mechanisms underlying the pharmacotherapy of schizophrenia and Parkinson’s disease.
• Signaling mechanisms and regulation of seven pass transmembrane G protein coupled receptors.

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Dean Lausier's video

Joan M. Lausier, Ph.D.
Associate Dean, Professor of Pharmaceutics
ladyjoan@uri.edu

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Research Interests:

• Design and evaluation of drug delivery systems,
  pharmaceutical processing, and formulation of cosmetics.

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Dr. Parang's video

Keykavous Parang, Pharm. D., Ph.D.
Professor of Medicinal Chemistry
kparang@uri.edu

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Research Interests

Our research is appropriately described as "the application of synthetic organic chemistry to problems in biology". Specific areas currently under investigation include:

• Designing Protein Kinase Inhibitors Through Target-Based Strategies Using Molecular Modeling, Synthetic and Biochemical Tools.
• Mechanistic Studies of Protein Tyrosine Kinase Activation by Metals.
• Novel Strategies in the Solid-Phase Synthesis.
• Novel Approaches in Designing Bifunctional Antiinfective agents.

Robert L. Rodgers, Ph.D.
Professor of Pharmacology and Toxicology
rrodgers@uri.edu

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Research Interests:

• Effects of diabetes and hypertension on the heart and hormonal regulation of cardiac function and metabolism.

Sara E. Rosenbaum, Ph.D.
Professor of Applied Pharmaceutical Sciences
sarar@uri.edu

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Research Interests:

• Understanding the dose response relationship and factors that effect this relationship. This area is studied through the development and application of pharmacokinetic and pharmacodynamic models.

David C. Rowley, Ph.D.
Associate Professor of Pharmacognosy
drowley@uri.edu

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Research Interests:

• Bioactive secondary metabolites produced by marine microorganisms.

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Dr. Seeram's video

Navindra Seeram, Ph.D.
Assistant Professor of Pharmacognosy
nseeram@mail.uri.edu

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Research Interests:

• Natural product drug discovery from terrestrial plants
• Medicinal foods for prevention and therapy of cancer, diabetes and Alzheimer’s disease
• Metabolism, bioavailability, tissue disposition and in vivo bioactivities of dietary phytochemicals
   

Zahir A. Shaikh
Professor of Pharmacology and Toxicology
zshaikh@uri.edu

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Research Interests:

• Toxicity of metals
• Nephrotoxicity and hepatotoxicity
• Oxidative stress as a mediator of toxic response
• Transcription factors and apoptosis

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Dr. Slitt's video

Angela Slitt, Ph.D.
Research Assistant Professor
aslitt@etal.uri.edu

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Research Interests:

• How expression of drug transporter expression in liver and kidney changes drug disposition
• How Resveratrol, a component of red wine, regulates transporter expression in liver
• The genetics of gallstone susceptibility during exposure to a high cholesterol diet

Matthew Stoner, Ph.D.
Research Assistant Professor of Molecular Toxicology
mstoner@uri.edu

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Research Interests:

• Nuclear receptor signaling
• Transcriptional regulation of liver gene expression
• Hypoxia versus normoxia
• Proteasome

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Research Interests:

• Identification and manipulation of natural product biosynthetic gene clusters for the purpose of discovering and modifying molecules useful in medicine.

Bingfang Yan, Ph.D.
Professor of Pharmacology and Toxicology
byan@uri.edu

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Research Interests:

• Genetic-based alteration on drug response

• Drugs, herbs, hormones, and their interaction

• Cancer: initiation, progression and chemoresistance

• Transcription regulation

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Dr. Zawia's video

Nasser H. Zawia, Ph.D.
Professor of Pharmacology and Toxicology
nzawia@uri.edu

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Research Interests:

• The developmental-basis of adult diseases.
• Environmental risk factors for Alzheimer’s disease
• Pinpointing potential biomarkers for Alzheimer’s disease.
• Developing drugs for the treatment of neurodegenerative diseases
   

Hossein Zia, Ph.D.
Professor of Pharmaceutics
hzia@uri.edu

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Research Interests:

• Formulation of drugs and peptides for nasal, ocular and oral delivery
• Microencapsulation of peptides and proteins as injectable and intranasal delivery products
• Basic research in area of physical pharmacy as applied to formulation development.

Emeritus Faculty
 

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Research Interests:

• Formulation and product development of conventional and biotechnology based drugs using controlled release technologies to provide intranasal, oral, opthalmic and parenteral delivery.

Yuzuru Shimizu, Ph.D.
Professor Emeritus
yshimizu@uri.edu

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Research Interests:

• Chemistry and Biochemistry of Marine Natural Products
• Toxigenicity Mechanisms of Marine Microorganisms
• Biosynthesis of Red Tide Toxins and Mechanism of Action of Toxins

Alvin K. Swonger, Ph.D.
Professor Emeritus
aks@uri.edu

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Research Interests:

• Development of instructional material for teaching pharmacology

Adjunct Faculty

The department is fortunate to draw upon the services of a number of off-campus scientists from both industry and government.  Those who currently hold adjunct faculty appointments are:

Beckert, Thomas E., Kirschenallee, Germany
Benoit, David G., Northeast Pharmaceutical Services
Birmingham, Bruce, Xeneca
Breur, Miklos M., The Gillette Company
Corvese, David, Alchemie Investments
Danish, Michele R., St. Joseph Health Services
Davis, Richard., DuPont Pharmaceuticals
Dedhiya, Mahendra, Roxane Laboratories, Inc.
Dudley, Michael, Microcide Pharmaceuticals, Inc.
Ette, Ene, Vertex Pharmaceutica
Gann, Kathryn L., Hoechst-Roussel Pharmaceuticals
Gerraughty, Robert J., Pharmaceutical Consultant
Grant, John, Blue Cross of Rhode Island
Himmel, Peter B., Himmel Health
Hoffman, H. Rainer, Lohmann Therapie Systeme, GMB H & Co
Holm, Alison, Private Law Practice
Joshi, Yatindra, Novartis Pharmaceuticals Corporation
Malick, Waseem, Hoffmann-LaRoche, Inc.
Marcoux, Rita, Carenetics Healthcare Management Consultants
Moffitt, Colleen, Pfizer, Inc.
Mojaverian, Parviz, Schering-Plough
Mollan, Matthew Jr., Park-Davis, Pfizer-Warner-Lambert, Inc.
Molzon, Justina, FDA
Monkhouse, Donald C., Private Consultant
Ortiz, Carlos, CVS Pharmacy
Perfetto, Eleanor M., Pharmaceutical Consultant
Rudnic, Edward, Pharmavene
Ruggiero, Laurie, Department of Psychology, URI
Ryan, Thomas, CVS Pharmacy
Sado, Pierre A., University of Rennes
Shah, Ajit, Pfizer, Inc.
Shah, Navnit, Hoffman-LaRoche, Inc.
Sienkiewicz, George, Faulding
Solis, Jon S., Westerly Dermatology
Squillante, Emilio, St. John's University
Szymanski, Dennis, American Pharmaceutical Partners
Tyle, Praveen, Pharmacia & Upjohn
Urbani, Lynne, Coordinated Health Partners, Inc..
Westrick, Edward, Rhode Island Quality Partners

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