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Faculty and Staff
Deng  

Wei Lu, Ph.D.

Assistant Professor
Department of Biomedical and Pharmaceutical Sciences
weilu@uri.edu
     

Research Interests

   Dr. Lu’s current research involves nanotechnology for cancer diagnosis and therapeutics--Theranostics. From nanotechnology to biomedical application and pharmaceutical development, the work is related to seeking the potentials for clinical translation, which includes photothermal therapy, molecular imaging, controlled release of chemotherapeutic agents and nucleic acids, and vaccine development for cancer theranostics.
     

Education

  

Ph.D., School of Pharmacy, Fudan University, Shanghai, China, 2005

B.S., School of Pharmacy, Fudan University, Shanghai, China, 2000
     
Selected Publications  

Melancon M*, Lu W*, Huang Q, Thapa P, Zhou D, Ng C, Li C. Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813. Biomaterials 2010; 31: 6567-73. (*equal contribution)

Lu W, Zhang G, Zhang R, Flores II LG, Huang Q, Gelovani JG, Li C. Tumor site-specific silencing of NF-κB p65 by targeted hollow gold nanospheres-mediated photothermal transfection. Cancer Research 2010; 70: 3177-88.

Lu W, Huang Q, Ku G, Wen X, Zhou M, Guzatov D, Brecht P, Su R, Oraevsky A, Wang LV, Li C. Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres. Biomaterials 2010; 31: 2617-26.

Lu W, Xiong C, Zhang G, Huang Q, Zhang R, Zhang JZ, Li C. Targeted photothermal ablation of murine melanomas with melanocyte-stimulating hormone analog-conjugated hollow gold nanospheres. Clinical Cancer Research 2009; 15: 876-86.

Lu W, Jiang W, Chen J, Yin M, Wang Z, Jiang X. Modulation of brain delivery and copulation by intranasal apomorphine hydrochloride. International Journal of Pharmaceutics 2008; 349: 196-205.

Lu W, Wan J, Zhang Q, She Z, Jiang X. Aclarubicin-loaded cationic albumin-conjugated pegylated nanoparticle for glioma chemotherapy in rats. International Journal of Cancer 2007; 120: 420-31.

Lu W, Sun Q, Wan J, She Z, Jiang XG. Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration. Cancer Research 2006; 66: 11878-87.

Lu W, Zhang Y, Tan YZ, Hu KL, Jiang XG, Fu SK. Cationic albumin-conjugated pegylated nanoparticles as novel drug carrier for brain delivery.Journal of Controlled Release 2005; 107: 428-48.

 
     
Honors & Awards  

2007

 National Excellent Doctoral Dissertation by Ministry of Education and Academic Degrees Committee of the State Council of the People’s Republic of China
     
Journal Reviewer  

Journal of Controlled Release, 2007-
International Journal of Pharmaceutics, 2007-