David C. Rowley, Ph.D.

Associate Professor of Pharmacognosy
Department of Biomedical and Pharmaceutical Sciences
drowley@uri.edu

Click here for information about the Natural Product Research Group

Research Interests

Bioactive secondary metabolites produced by marine microorganisms.

Education

Ph.D., University of California, San Diego, 2001

B.S., The Pennsylvania State University, 1990

Long RA, Rowley DC, Zamora E, Liu J, Douglas H. Bartlett DH, Azam F. Antagonistic interactions among marine bacteria impede the spread of Vibrio cholerae.  Appl. Environ. Microbiol. 2005, 71: 8531-8536.

Socha AM, Garcia D, Sheffer R, Rowley DC. Antibiotic bisanthraquinones produced by a streptomycete isolated from a cyanobacterium associated with Ecteinascidia turbinata. J. Nat. Prod. 2006, 69: 1070-1073.

Socha AM, LaPLante KL, Rowley DC. New bisanthraquinone antibiotics and semi-synthetic derivatives with potent activity against clinical Staphylococcus aureus and Enterococcus faecium isolates.  Bioorg. Med. Chem. 2006, 14:8446-54.

Socha AM, Long RA, Rowley DC. New bacillamides from a hypersaline microbial mat bacterium. J. Nat. Prod. 2007, 70:1793-1795.

Clark BR, Engene N, Teasdale ME, Rowley DC, Matainaho T, Valeriote FA, Gerwick WH. Natural products chemistry and taxonomy of a Blennothrix species of marine cyanobacterium. J. Nat. Prod. 2008, 71: 1530-1537.
Teasdale M, Liu J, Wallace J, Rowley DC. Secondary metabolites produced by a marine Halobacillus salinus that inhibit quorum sensing controlled phenotypes in Gram-negative bacteria. Appl. Environ. Microbiol. 2009, 75(3): 567-572.

 Socha AM, LaPlante KL, Russell DJ, Rowley DC.  Structure-activity studies of echinomycin antibiotics against drug-resistant and biofilm-forming Staphylococcus aureus and Enterococcus faecalis.  Bioorg. Med. Chem. Lett. 2009, 19: 1504-1507.

 Forschner S, Sheffer R, Rowley DC, Smith DC. Microbial diversity of deeply buried Arctic prokaryotic communities.  Environ. Microbiol. 2009, 11(3): 630-639.