Kerry LaPlante, Pharm.D.

Assistant Professor
Department of Pharmacy Practice
kerrytedesco@uri.edu

Publications | Honors & Awards

Click here for information about Dr. LaPlante's lab

Research Interests

Dr. LaPlante is an associate professor of pharmacy and adjunct clinical professor of medicine at the University of Rhode Island and the Alpert Medical School of Brown University, respectively. She is also an infectious diseases pharmacotherapy specialist and the Director of the infectious diseases research program at the Providence Veterans Affairs Medical Center. She is nationally recognized for her work in the treatment, virulence inhibition, control and prevention of methicillin-resistant Staphylococcus aureus (MRSA) where she has authored more than 75 peer-reviewed journal articles, abstracts and textbook chapters.

Research Expertise

Infectious Diseases in vitro Division (2004 present)

• Methicillin Resistant Staphylococcus aureus (MRSA)
• Biofilm and toxin production in MRSA
• Pharmacodynamic interactions of combination therapy
• Antibiotic lock Therapy (ALT)
• Infection control and decolonization of MRSA
• Investigating novel agents for activity against gram positive pathogens

Anti-infective Outcomes Research Division (2008 to present):

• Pharmacoepidemiologic Research
• Comparative Effectiveness Research/Studies
• Outcomes Research/Studies
• Risk Factors Research/Studies
• Drug Utilization Research/Studies
• Drug Safety Research/Studies
• Infectious Disease Epidemiologic Research/Studies
  

Clinical Practice Site

Veterans Affairs Medical Center

Education

Bachelor of Science, Biology, Canisius College, Buffalo, NY, 1996

Bachelor of Science, Pharmaceutical Sciences Wayne State University, College of Pharmacy Detroit, MI, 2000

Doctor of Pharmacy, Wayne State University, College of Pharmacy Detroit, MI, 2002

Experience

Adjunct Clinical Assistant Professor of Medicine, Warren Alpert Medical School of Brown University, Department of Medicine of the Division of Biology and Medicine and Infectious Diseases, Brown University, Providence, RI; 2007 - present

Assistant Professor of Pharmacy, URI College of Pharmacy, Department of Pharmacy Practice, University of Rhode Island

Clinical Pharmacy Specialist, Infectious Diseases, Veterans Affairs Medical Center, Providence, RI

DePestel DD, Benninger M, Danziger L, LaPlante KL, May C, Luskin A, Pichichero M, Hadley JA. Cephalosporin Use in the Treatment of Penicillin-Allergic Patients; Status: in press. Journal of the American Pharmacists Association.

LaPlante KL, Rybak MJ. Andes D, Craig WA. Community Associated-Methicillin Resistant Staphylococcus aureus isolates versus Daptomycin, Clindamycin, Doxycycline, Linezolid and Trimethoprim/Sulfamethoxazole in an in vitro Pharmacodynamic model.  Antimicrob Agents Chemother. 2008 Apr 14, Eur ahead of print

LaPlante KL, Mersfelder TL, Ward KE, Quilliam, BJ. Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting. Pharmacotherapy. 2008 Jan;28(1):82-9.

Attwood RJ, LaPlante KL. Telavancin, a novel lipoglycopeptide antimicrobial agent. Am J Health Syst Pharm. 2007 Nov 15;64(22):2335-48.

LaPlante KL Mermel LA.. In Vitro Activity of Daptomycin and Vancomycin Lock Solutions on StaphylococcalBiofilms in a Central Venous Catheter Model. Nephrol. Dial. Transplant. 22: 2239-2246

LaPlante KL, Rybak MJ, Tsuji B, Lodise, T, Kaatz GW,  Fluoroquinolone Resistance in Streptococcus pneumoniae, Area Under the Curve: Minimum Inhibitory Concentration Ratio and the Probability of Resistance Development with Gatifloxacin, Gemifloxacin, Levofloxacin, and Moxifloxacin. Antimicrob Agents Chemother. 2007 Feb 12.

LaPlante KL, Rybak MJ, Amjad A, Kaatz GW.  Antimicrobial Susceptibility and Staphylococcal Chromosomal Cassette mec Type in Community- and Hospital-Associated Methicillin-Resistant Staphylococcus aureus. Pharmacotherapy. 2007 Jan;27(1):3-10.

LaPlante KL, In vitro activity of lysostaphin, mupirocin, and tea tree oil against clinical methicillin-resistant Staphylococcus aureus. Diagn Microbiol Infect Dis. 2006 Nov 30

Socha A, LaPlante KL, Rowley DR, New bisanthraquinone antibiotics and semi-synthetic derivatives with potent activity against clinical Staphylococcus aureus and Enterococcus faecium isolates. Bioorg Med Chem. 2006 Dec 15;14(24):8446-54. Epub 2006 Sep 18

LaPlante KL, Rybak MJ, Leuthner KL, Chin JN Impact of Enterococcus faecalis on the bactericidal activities of arbekacin, daptomycin, linezolid, and tigecycline against methicillin-resistant Staphylococcus aureus in a mixed-pathogen pharmacodynamic model. Antimicrob Agents Chemother. 2006 Apr;50(4):1298-303.

Ward KE, Mersfelder TL, LaPlante KL. Oritavancin--an investigational glycopeptide antibiotic.
Expert Opin Investig Drugs. 2006 Apr;15(4):417-29. Review.

Rybak MJ, LaPlante KL. Community-associated methicillin-resistant Staphylococcus aureus: a review. Pharmacotherapy. 2005 Jan;25(1):74-85. Review.

LaPlante KL, Rybak MJ.  Impact of high-inoculum Staphylococcus aureus on the activities of nafcillin, vancomycin, linezolid, and daptomycin, alone and in combination with gentamicin, in an in vitro pharmacodynamic model. Antimicrob Agents Chemother. 2004 Dec;48(12):4665-72.

LaPlante KL, Rybak, MJ. Daptomycin - a novel antibiotic against Gram-positive pathogens. Expert Opin Pharmacother. 2004 Nov;5(11):2321-31. Review.

LaPlante KL, Rybak MJ. Clinical glycopeptide-intermediate staphylococci tested against arbekacin, daptomycin, and tigecycline.  Diagn Microbiol Infect Dis. 2004 Oct;50(2):125-30. 

Tedesco KL, Rybak MJ. Daptomycin; Drug Review.  Pharmacotherapy 2004;24 (1):41-57.