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College of Pharmacy > Department of Biomedical and Pharmaceutical Sciences > Dr. King's Lab

Dr. Roberta S. King, Ph.D.
Publications

 
 
 

15. Yalcin EB, Struzik SM, King RS (2008) Allosteric Modulation of SULT2A1 by Celecoxib and Nimesulide: Computational Analyses. Drug Metabolism Letters, 2(3).

14. Yuan Z, Jha G, McGregor M, and King RS (2007) Metabolites of the carcinogen 2-amino-alpha-carboline formed in male Sprague-Dawley rats in vivo, and in rat hepatocyte and human HepG2 cell incubates. Chemical Research in Toxicology, 20:497-503.

13. King RS, Ghosh AA, Wu J (2006) Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents. Current Drug Metabolism, 7(7):745-753.

12. Huber WW, Teitel CH, Coles BF, King RS, Wiese FW, Kaderlik KR, Casciano DA, Shaddock JG, Mulder GJ, Ilett KF, Kadlubar FF. (2004) Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities. Environmental and Molecular Mutagenesis, 44:265-276.

11. Banoglu E and King RS  (2002) Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate. European Journal of Drug Metabolism and Pharmacokinetics, 27(2): 135-140.

10. Banoglu E, Jha GG and King RS (2001) Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate. European Journal of Drug Metabolism and Pharmacokinetics, 26(4): 235-240.

9. King RS, Sharma V, Pedersen LC, Kakuta Y, Negishi M and Duffel MW (2000) Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV. Chemical Research in Toxicology, 13(12):1251-1258.

8. King RS, Teitel CH and Kadlubar FF (2000) In vitro bioactivation of N-hydroxy-2-amino-a-carboline. Carcinogenesis, 21(7):1347-1354.

7. King RS, Kadlubar FF and Turesky RJ (2000) In vivo metabolism of heterocyclic amines, in Food Borne Carcinogens: Heterocyclic Amines (Sugimura T and Nagao M eds) pp. 90-111, John Wiley & Sons, London.

6. King RS, Teitel CH, Shaddock JG, Casciano DA and Kadlubar FF (1999) Detoxication of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative. Cancer Letters, 143:167-171.

5. Lewis AJ, Walle UK, King RS, Kadlubar FF, Falany CN and Walle T (1998) Bioactivation of the cooked-food mutagen N-hydroxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) by estrogen sulfotransferase in cultured human mammary epithelial cells. Carcinogenesis 19(11):2049-2053.

4. Snyderwine EG, Sadrieh N, King RS and Schut HAJ (1998) Formation of DNA adducts of the food-derived mutagen 2-amino(a)carboline and bioassay of mammary gland carcinogenicity in Sprague-Dawley rats. Food and Chemical Toxicology 36(12):1033-1040.

3. King RS and Duffel MW (1997) Oxidation-dependent inactivation of aryl sulfotransferase IV by primary N-hydroxy arylamines during in vitro assays. Carcinogenesis 18(4):843-849.|

2. Raza H, King RS, Squires RB, Guengerich FP, Miller DW, Freeman JP, Lang NP and Kadlubar FF (1996) Metabolism of 2-amino-a-carboline: A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2. Drug Metab. Dispos. 24(4):395-400.

1. Duffel MW, Modi RB and King RS (1992) Interactions of a primary N-hydroxy arylamine with rat hepatic aryl sulfotransferase IV. Drug Metab. Dispos. 20:339-341.


 

 
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