Department of Biomedical and Pharmaceutical Sciences
University of Rhode Island, Kingston, Rhode Island
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Publications (Updated May 14, 2012):

106. Agarwal, H. K., Chhikara, B. S., Hanley, M. J., Ye, G., Doncel, G. F., Parang, K. Synthesis and biological evaluation of fatty acyl ester derivatives of (-)-2',3'-dideoxy-3'-thiacytidine. J. Med. Chem. (2012) DOI: 10.1021/jm300492q.

105. Agarwal, H. K., Chhikara, B. S., Quiterio, M., Doncel, G. F., Parang, K. Synthesis and anti-HIV activities of glutamate and peptide conjugates of nucleoside reverse transcriptase inhibitors. J. Med. Chem. (2012) 55, 2672-2687.

104. Chhikara, B. S., Mandal, D., Parang, K. Synthesis, anticancer activities, and cellular uptake studies of lipophilic derivatives of doxorubicin succinate. J. Med. Chem. (2012) 55, 1500-1510.

103. Munthayala, M., Chhikara, B., Parang, K., Kumar, A. Ionic liquid-supported synthesis of sulfonamides and carboxamides. ACS Combinatorial Science (2012) 14, 60-65.

102. Kameshwara Rao, V., Chhikara, B.S., Tiwari, R., Nasrolahi Shirazi, A., Parang, K., Kumar, A. One-pot regioselective synthesis of tetrahydroindazolones and evaluation of their anti-proliferative and Src kinase inhibitory activities. Bioorg. Med. Chem. Lett. (2012) 22, 410-414. 

101. Rao, M. S., Chhikara, B. S., Tiwari, R., Shirazi, A. N., Parang, K., Kumar, A. Microwave-assisted and scandium triflate catalyzed synthesis of tetrahydrobenzo[α]xanthen-11-ones. Monatsh. Chem. (2012) 143, 263-268.

100. Agarwal, H. K., Doncel, G. F., Parang, K. Synthesis and anti-HIV activities of Suramin conjugates of 3′-fluoro-2′,3′-dideoxythymidine and 3′-azido-2′,3′-dideoxythymidine. Med. Chem. 2012, 8, 193-197.

99. Muthyala, M. J., Chhikara, B. S., Parang, K., Kumar, A. Ionic-liquid-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene— An efficient and recyclable organocatalyst for Michael addition to α,β-unsaturated ketones. Can. J. Chem. (2012) 90, 290-297.

98. Tiwari, R., Parang K. Conformationally constrained peptides as protein tyrosine kinase inhibitors. Current Pharmaceutical Design (2012), in press, PMID 22571654.

97. Mandal, D., Nasrolahi Shirazi, A., Parang, K. Cell-penetrating homochiral cyclic peptides as nuclear-targeting molecular transporters. Angew. Chem. Int. Ed. (2011) 50, 9633-9637.

96. Fallah-Tafti, A., Foroumadi, A., Tiwari, R., Shirazi, A. N., Hangauer, D. G., Bu, Y., Akbarzadeh, T., Parang, K., Shafiee, A. Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities. Eur. J. Med. Chem. (2011) 46, 4853-4858.

95. Kathuria, A., Jalal, S., Tiwari, R., Nasrolahi Shirazi, A., Gupta, S., Kumar, S., Parang, K., Harma, S. K. Substituted coumarin derivatives: Synthesis and evaluation of antiproliferative and Src kinase inhibitory activities. Chemistry Biology Interface (2011) 1 (2), 279-296.

94. Kumar, A., Ahmad, I, Chhikara, B. S., Tiwari, R., Mandal, D., Parang, K. Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities. Bioorg. Med. Chem. (2011) 21, 1342-1346.

93. Agarwal, H. K., Loethan, K., Mandal, D., Doncel, G. F. Parang, K. Synthesis and anti-HIV activities of fatty acyl ester derivatives of 2',3'-didehydro-2',3'-dideoxythymidine. Bioorg. Med. Chem. (2011) 21, 1917-1921.

92. Chhikara, B. S., St. Jean, N., Mandal, D., Kumar, A., Parang, K. Fatty-acyl amide derivatives of doxorubicin: Synthesis and in vitro anticancer activities. Eur. J. Med. Chem. (2011) 46, 2037-2042.

91. Ahmadibeni, Y., Tiwari, R., Swepson, C., Pandhare, J., Dash, C., Doncel, G. F., Parang, K. Synthesis and anti-HIV activities of bis-(cycloSaligenyl) pronucleotides derivatives of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine. Tetrahedron Lett. (2011) 52, 802-805.

90. Kumar, D., Buchi Reddy, V., Kumar, A., Mandal, D., Tiwari, R., Parang, K. Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activity. Bioorg. Med. Chem. Lett. (2011) 2, 449-452.

89. Gupta, A., Mandal, D., Ahmadibeni, Y., Parang, K., Bothun, G. Hydrophobicity drives the non-specific cellular uptake of short cationic peptide ligands. Eur. Biophysics J. (2011) 40, 727-736.

88. Fallah-Tafti, A., Tiwari, R., Shirazi, A. N., Akbarzadeh, T., Mandal, D., Shafiee, A., Parang, K. , Foroumadi, A. 4-Aryl-4H-Chromene-3-carbonitrile derivatives: Evaluation of Src kinase inhibitory and anticancer activities. Med. Chem. (2011) 7, 466-472.

87. Dash, C., Ahmadibeni, Y., Hanley, M. J., Pandhare, J., Gotte, M., Le Grice, S. F. J., Parang, K. Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside beta-triphosphates. Bioorg. Med. Chem. Lett. (2011) 21, 3519-3522.

86. Rao, V. K., Chhikara, B. S., Nasrolahi Shirazi, A. N., Tiwari, R., Parang, K., Kumar, A. 3-Substituted indoles: One-pot synthesis and evaluation of anticancer and Src kinase inhibitory activities. Bioorg. Med. Chem. (2011)  21, 3511-3514.

85. Chhikara, B. S., Parang, K. Development of cytarabine prodrugs and delivery systems for leukemia treatment. Expert Opin. Drug Del. (2010) 7, 1399-1414.

84. Agarwal, H. K., Kumar, A., Doncel, G. F., Parang K. Synthesis, antiviral and contraceptive activities of nucleoside-sodium cellulose sulfate acetate and succinate conjugates. Bioorg. Med. Chem. Lett. (2010) 20, 6993-6997.

83. Chhikara, B. S., Mandal, D., Parang, K. Synthesis and evaluation of fatty acyl ester derivatives of cytarabine as anti-leukemia agents. Eur. J. Med. Chem. (2010) 45, 4601-4608.

82. Sharma, D., Bhatia, S., Sharma, R. K., Tiwari, R., Olsen, C. E., Mandal, D., Lehmann, J., Parang, K., Parmar, V. S., Prasad, A. S. Synthesis, Src kinase inhibitory and anticancer activities of 1-substituted 3-(N-alkyl-N-phenylamino)propane-2-ols. Biochimie ( 2010) 92, 1164-1172.

81. Ahmadibeni, Y., Dash, C., Le Grice, S. F. J., Parang K. Solid-phase synthesis of 5'-O-beta,gamma-methylenetriphosphate derivatives of nucleosides and evaluation of their inhibitory activity against HIV-1 reverse transcriptase. Tetrahedron Lett. (2010) 51, 3010-3013.

80. Tiwari, R., Brown, A., Narramaneni, S., Sub, G., Parang, K. Synthesis and evaluation of conformationally constrained peptide analogues as the Src SH3 domain binding ligands. Biochimie (2010) 92, 1153-1163.

79. Ahmadibeni, Y., Dash, C., Hanley, M. J., Le Grice, S. F. J., Agarwal, H. K., Parang K. Synthesis of nucleoside 5'-O-alpha,beta-methylene-betatriphosphates and evaluation of their potency towards inhibition of HIV-1 reverse transcriptse. Org. Biomol. Chem. (2010) 8, 1271-1274..

78. Ye, G., Gupta, A., Delluca, R., Parang, K., Bothun, G. D. Bilayer distribution and liposome restructuring by a homologous series of small Arg-Rich synthetic peptides. Colloids and Surfaces B.:Biointerfaces (2010) 76, 76-81.

77. Penugonda, S., Agarwal, H. K., Parang, K., Mehvar, R. Plasma pharmacokinetics and tissue disposition of novel dextran-methylprednisolone conjugates with peptide linkers in rats. J. Pharmaceutical Sci. (2010), 99, 1627-1637.

76. Tiwari, R., Parang K. Protein conjugates of SH3 domain ligands and ATP-competitive inhibitors as bivalent inhibitors of protein kinases. ChemBioChem (2009) 10, 2445-2448.

75. Carballeira, N. M., Miranda, C., Parang, K. The first total synthesis of the ( )-4-methoxydecanoic acid: a novel antifungal fatty acid. Tetrahedron Lett. (2009) 50, 5699-5700.

74. Ye, G., Schuler, A., Ahmadibeni, Y., Morgan, J. R., Faruqui, A., Huang, K., Sun, G., Zebala, J. A., Parang, K. Synthesis and evaluation of peptides containing iminodiacetate groups as binding ligands of the Src SH2 domain. Bioorg. Chem. (2009) 37, 133-142.

73. Ahamadibeni, Y., Tiwari, R., Sun, G., Parang, K. Synthesis of nucleoside mono-, di-, and triphosphoramidates from solid-phase cycloSaligenyl phosphitylating reagents. Org. Lett. (2009) 11, 2157-2160.

72. Ahmadibeni, Y., Parang, K. Solid-supported reagents for synthesis of nucleoside monothiophosphates, dithiodiphosphates, and trithiotriphosphates. Curr. Protoc. Nucleic Acid Chem.(2009) Chapter 13:Unit13.9.

71. Parang, K., Doncel, G., Agarwal, H. K. Substituted nucleoside derivatives and antiviral and antimicrobial properties. PCT Int. Appl. (2009) WO 2009009625.

70. Agarwal, H. K., Doncel, G., Parang, K. Synthesis and anti-HIV activities of phosphate triester derivatives of 3′-fluoro-2′,3′-dideoxythymidine and 3′-azido-2′,3′-dideoxythymidine. Tetrahedron Lett. (2008) 49, 4905-4907.

69. Ye, G., Tiwari, R., Parang K. Development of Src tyrosine kinase substrate binding site inhibitors. Curr. Opin. Investig. Drugs (2008) 9, 605-613.

68. Ahmadibeni, Y., Parang, K. Solid-supported diphosphitylating and triphosphitylating reagents for nucleoside modification. Curr. Protoc. Nucleic Acid Chem. (2008) Chapter 13:Unit13.8.

67. Penugonda, S., Kumar, A., Agarwal, H. K., Parang, K., Mehvar, R. Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: Effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates. J. Pharm. Sci. (2008) 97, 2649-2664.

66. Ahmadibeni, Y., Parang, K. Solid-phase synthesis of symmetrical 5’,5’-dinucleoside mono-, di-, tri-, and tetraphosphodiesters. Org. Lett. (2007) 9, 4483-4486.

65. Bhandari, R., Saiardi, A., Ahmadibeni, Y., Snowman, A. M., Resnick, A. C., Kristiansen, T. Z., Molina, H., Pandey, A., Werner, Jr. J. K., Juluri, K. R., Xu, Y., Prestwich, G. D., Parang, K., Snyder, S. H. Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proc. Nat. Acad. Sci. U.S.A. (2007) 104, 15305-15310.

64. Chimalakonda, C., Agarwal, H., Kumar, A., Parang, K., Mehvar, R. Synthesis, analysis, in vitro characterization, and in vivo disposition of a lamivudine-dextran conjugate for selective antiviral delivery to the liver. Bioconjugate Chem. (2007) 18, 2097-2108.

63. Ye, G., Nam, N. H., Saleh,A., Kumar, A., Sun, G., Shenoy, D. B., Amiji, M. M., Parang,K. Cellular delivery of phosphopeptides with tripodal peptide analogues. J. Med. Chem. (2007) 50, 3604-3617.

62. Ahmadibeni, Y., Hanley, M., White, M., Ayrapetov, M., Lin, X., Sun, G., Parang, K. Metal-binding properties of a dicysteine-containing motif in protein tyrosine kinases. ChemBioChem (2007) 8, 1592-1605.

61. Carballeira, N. M., O’Neil, R., Parang, K. Synthesis and antifungal properties of alpha-methoxy and alpha-hydroxyl substituted 4-thiatetradecanoic acids. Chem. Phys. Lipids (2007) 150, 82-88.

60. Ahmadibeni, Y., Parang, K., Synthesis and evaluation of oligodeoxynucleotides containing diphosphodiester internucleotide linkages. Angew. Chem. Int. Ed. (2007) 46, 4739-4743.

59. Kumar, A., Wang, Y., Lin, X., Sun, G., Parang, K. Synthesis and evaluation of 3-phenylpyrazolopyrimidine-peptide conjugates as Src tyrosine kinase inhibitors. ChemMedChem (2007) 2, 1346-1360.

58. Agarwal, H. K., Parang, K. Application of solid-phase chemistry for the synthesis of 3’-fluoro-3’-deoxythymidine. Nucleosides, Nucleotides& Nucleic Acids (2007) 26, 317-322.

57. Parang, K., Ahmadibeni, Y. Solid-phase synthesis of modified oligonucleotides containing diphosphodiester inter-nucleotide linkages. PCT Int. Appl. (2007) WO 2007030227.

56. Gu,X., Wang, Y., Kumar, A., Ye, G., Parang, K., Sun, G. Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase. J. Med. Chem. (2006) 49, 7532-7539.

55. Kumar, A., Ye, G., Wang, Y., Lin, X., Sun, G., Parang, K. Synthesis and structure-activity relationships of linear and conformationally constrained peptide analogs of CIYKYY as Src tyrosine kinase inhibitors. J. Med. Chem. (2006) 49, 3395-3401.

54. Carballeira, N. M., Sanabria, D., Cruz, C., Parang, K., Wan, B., Franzblau, S. 2,6-Hexadecadiynoic acid and 2,6-nondecadiynoic acid – Novel synthesized acetylenic fatty acids as potent antifungal agents. Lipids (2006) 41, 507-511.

53. Ahmadibeni, Y., Parang, K. “Application of a solid-phase beta-triphosphitylating reagent in the synthesis of nucleoside beta-triphosphates. J. Org. Chem. (2006) 71, 5837-5839.

52. Ahmadibeni, Y., Parang, K. Solid-phase synthesis of dinucleoside and nucleoside-carbohydrate phosphodiesters and thiophosphodiesters. J. Org. Chem. (2006) 71, 6693-6696.

51. Lee, S., Ayrapetov, M. K., Kemble, D., Parang, K., Sun, G. Docking-based substrate recognition by the catalytic domain of a protein tyrosine kinase, the C-terminal Src kinase. J. Biol. Chem. (2006) 281, 8183-8189.

50. Lin, X., Wang, Y., Ahmadibeni, Y., Parang, K., Sun, G. Structural basis for domain-domain communication in a protein tyrosine kinase, Csk. J. Mol. Biol. (2006) 357, 1263-1273.

49. Ayrapetov, M. K., Wang, Y.-H., Xiaofeng, L., Gu X., Parang, K., Sun, G. Conformational basis for SH2-pTYR527 binding in Src inactivation. J. Biol. Chem. (2006) 281, 23776-23784.

48. Kumar, A., Ye, G., Ahmadibeni, Y., Parang, K. Synthesis of polymer-bound 4-acetoxy-3-phenylbenzaldehyde derivatives: Applications in solid-phase organic synthesis. J. Org. Chem. (2006) 71, 7915-7918.

47. Parang, K. Editor. Novel approaches in designing anti-HIV microbicides and anti-HIV Agents. Curr. Pharm. Des. (2005) 11, 123 pp.

46. Ahmadibeni, Y., Parang, K. Selective diphosphorylation, dithiodiphosphorylation, triphosphorylation, and trithiotriphosphorylation of unprotected carbohydrates and nucleosides. Org. Lett. (2005) 7, 5589-5592.

45. Parang, K., Sun, G. Recent advances in the discovery of Src kinases inhibitors. Expert Opin. Ther. Patents (2005) 15, 1183-1207.

44. Ye, G., Ayrapetov, M., Nam, N. H., Sun, G., Parang, K. Solid-phase binding assays of peptides using EGFP-Src SH2 domain fusion protein and biotinylated Src SH2 domain. Bioorg. Med. Chem. Lett. (2005) 15, 4994-4997.

43. Carballeira, N. M., O'Neill, R., Parang, K. Total synthesis and further scrunity of the in vitro antifungal activity of 6-nonadecynoic acid. Arch. Pharm.-Pharm. Med. Chem. (2005) 338, 441-443.

42. Ayrapetov, M. K., Nam, N. H., Ye, G. Kumar, A., Parang, K., Sun, G. Functional diversity of Csk, Chk, and Src SH2 domains due to a single residue variation. J. Biol. Chem. (2005) 280, 25780-25787.

41. Parang, K., Nam, N. H. Sardari, S. Preparation of azole monosaccharide as antifungal agents. PCT Int. Appl. 006860 (2005) 62 pp, U.S. Patent 7,351,731, April 2008.

40. Ahmadibeni, Y., Parang, K. Polymer-bound oxathiaphospholane: A solid-phase reagent for regioselective monothiophosphorylation and monophosphorylation of unprotected nucleosides and carbohydrates. Org. Lett. (2005) 7, 1955-1958.

39. Carballeira, N. M., O'Neill, R., Parang K. Racemic and optically active 2-methoxy-4-oxatetradecanoic acids: Novel synthetic fatty acids with selective antifungal properties. Chem. Phys. Lipids (2005) 136, 47-54.

38. Parang, K., Sun, G., Kumar, A., Nguyen, N. H., Wang, Y.-H., Ye, G. Bisubstrate inhibitors of protein tyrosine kinases as therapeutic agents. PCT Int. Appl. WO 117932 (2005), 74 pp.

37. Hines, A. C., Parang, K., Kohanski, R. A., Hubbard, S. R., Cole, P. A. Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: Molecular yardsticks for analyzing catalytic mechanism and inhibitor design. Bioorg. Chem. (2005) 33, 285-297.

36. Lin, X., Ayrapetov, M. K., Lee, S., Parang, K., Sun, G. Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk. Biochemistry (2005) 44, 1561-1567.

35. Ahmadibeni, Y., Parang, K. Solid-phase reagents for selective monophosphorylation of carbohydrates and nucleosides. J. Org. Chem. (2005) 70, 1100-1103.

34. Parang, K., Sun, G. Protein kinase inhibitors in drug discovery. Drug Discovery Handbook, 2005, Wiley-Interscience, New Jersey, Ed. Gad, S. C. 1191-1257.

33. Parang, K., Sun, G. Design strategies for protein kinases inhibitors. Current Opinions In Drug Discovery (2004) 7, 630-638.

32. Nam, N. H., Lee, S., Ye, G., Sun, G., Parang, K. ATP-phosphopeptide conjugates as inhibitors of Src tyrosine kinases. Bioorg. Med. Chem. (2004) 12, 5753-5766.

31. Nam, N. H., Sardari, S., Selecky, M., Parang, K. Carboxylic acids and phosphate ester derivatives of fluconazole: synthesis and antifungal activities. Bioorg. Med. Chem. (2004) 12, 6255-6269.

30. Schmidt, B., Jiricek, J., Titz, A., Ye, G., Parang, K. Copper dipicolinates as peptidomimetic ligands for the Src SH2 domain. Bioorg. Med. Chem. Lett. (2004) 14, 4203-4206.

29. Nam, N. H., Pitts, R., Sun, G., Sardari, S., Tiemo, A., Xie, M., Yan, B., Parang, K. Design of tetrapeptide ligands as inhibitors of the Src SH2 domain. Bioorg. Med. Chem. (2004) 12, 779-787.

28. Nam, N.-H., Ye, G., Sun, G., Parang, K. Conformationally constrained peptide analogues of pTyr-Glu-Glu-Ile as inhibitors of the Src SH2 domain binding. J. Med. Chem. (2004) 47, 3131-3141.

27. Carballeira, N. M., Ortiz, D., Parang, K., Sardari, S. Total synthesis and in vitro antifungal activity of 2-methoxytetradecanoic acid. Arch. Pharm.-Pharm. Med. Chem. (2004) 337, 152-155.

26. Force, T., Kuida, K., Parang, K., Kyriakis, J. M. Inhibitors of protein kinase signaling pathways: emerging therapies for cardiovascular disease. Circulation (2004) 109, 1196-1205.

25. Lee, S., Lin, X., Nam, N. H., Parang, K., Sun, G. Determination of the substrate-docking site of protein tyrosine kinase Csk. Proc. Nat. Acad. Sci. U.S.A. (2003) 100, 14707-14712.

24. Sardari, S., Pourmorad, F., Tiemo, A., Nam, H., Parang, K. Protein kinases and their modulation in the central nervous system. Current Medicinal Chemistry-CNS (2003) 3, 341-364.

23. Nam, N. H., Sardari, S., Parang, K. Reactions of solid supported reagents and solid supports with alcohols and phenols through their hydroxyl functional group. J. Comb. Chem. (2003) 5, 479-546.

22. Parang, K., Preface, Anti-HIV design, Bentham Science Publishers, Hilversum, Current Pharm. Design (2003) 9, 22.

21. Nam, N. H., Parang, K. Current Drug Targets for Anticancer Drug Discovery. Current Drug Targets (2003), 4, 159-179.

20. Parang, K., Cole, P. A. Bisubstrate inhibitors of protein kinases. Pharmacology and Therapeutics (2002) 93, 145-157.

19. Parang, K. Polymer-supported reagents for methylphosphorylation and phosphorylation of Carbohydrates. Bioorg. Med. Chem. Lett. (2002) 12, 1863-1866.

18. Parang, K., Kohn, J. A., Saldahna, A., Cole, P. A. Development of photo-crosslinking reagents for protein kinase-substrate interactions. Febs Letters (2002) 520, 156-160.

17. Parang, K., Preface, Anti-HIV design, Bentham Science Publishers, Hilversum, Current Pharm. Design (2002) 8, 8.

16. Parang, K., Fournier, E. J.-L., Hindsgaul, O. A solid phase reagent for the capture phosphorylation of carbohydrate and nucleosides. Org. Lett. (2001)3, 307-309.

15. Courtney, A., Cole, P. A., Parang, K., Ablooglu, A., Kohanski, R. Bisubstrate inhibitors of kinases. PCT Int. Appl. WO 0170770 (2001) , 39 pp,US Patent 7,045,617 B2 May 2006.

14. Parang, K., Till, J. H., Ablooglu, A. J., Kohanski, R. A., Hubbard, S. R., Cole, P. A. Mechanism-based design of a protein kinase inhibitor. Nature Structural Biology (2001) 8, 37-41.

13. Parang, K., Wiebe, L. I., Knaus, E. E. Novel approaches in designing prodrugs of AZT. Current Medicinal Chemistry (2000) 7, 995-1039.

12. Kim, K., Parang, K., Lau, O. D., Cole, P. A. Tyrosine analogs as alternative substrates for protein tyrosine kinase Csk: insights into substrate selectivity and catalytic mechanism. Bioorg. Med. Chem. (2000) 8, 1263-1268.

11. Ablooglu, A. J., Till, J. K., Kim, K., Parang, K., Cole, P. A., Hubbard, S. R., Kohanski, R. A. Probing the catalytic mechanism of the insulin receptor kinase with a tetrafluorotyrosine-containing peptide substrate. J. Biol. Chem. (2000) 275, 30394-30398.

10. Parang, K., Wiebe, L. I., Knaus, E. E., Huang, J. S., Tyrrell, D. L. In vitro anti-hepatitis B virus activities of 5’-O-myristoyl analogue derivatives of 3’-fluoro-2’,3’-dideoxythymidine (FLT) and 3’-azido-2’,3’-dideoxythymidine (AZT). J. Pharm. Pharmaceut. Sci. (1998) 1, 107-113.

9. Parang, K., Knaus, E. E., Wiebe, L. I. Synthesis, in vitro anti-HIV activity, and biological stability of 5’-O-myristoyl analogue derivatives of 3’-fluoro-2’,3’-dideoxythymidine (FLT) as potential prodrugs of FLT. Nucleosides & Nucleotides (1998) 17, 987-1008.

8. Parang, K., Wiebe, L. I., Knaus, E. E. In vivo pharmacokinetic parameters, liver and brain uptake of (±)-3’-azido-2’,3’-dideoxy-5’-O-(2-bromomyristoyl)thymidine as potential prodrug of 3’-azido-3’-deoxythymidine. J. Pharm. Pharmacol. (1998) 50, 989-996.

7. Parang, K., Knaus, E. E., Wiebe, L. I. Synthesis, in vitro anti-HIV structure-activity relationships and stability of 5’-O-myristoyl analogue derivatives of 3’-azido-2’,3’-dideoxythymidine as potential prodrugs of 3’-azido-2’,3’-dideoxythymidine (AZT). Antiviral. Chem. Chemother. (1998) 9, 311-323.

6. Parang, K., Wiebe, L. I., Knaus, E. E. Syntheses and biological evaluation of 5’-O-myristoyl derivatives of thymidine against human immunodeficiency virus (HIV-1). Antiviral. Chem. Chemother. (1997) 8, 417-427.

5. Parang, K., Wiebe, L. I., Knaus, E. E., Huang, J. S., Tyrrell, D. L., Csizmadia, F. In vitro antiviral activities of myristic acid analogs against human immunodeficiency and hepatitis viruses. Antiviral Research(1997) 34, 75-90.

4. Parang, K., Knaus, E. E., Wiebe, L. I., Sardari, S., Daneshtalab, M., Csizmadia, F. Synthesis and antifungal activities of myristic acid analogs. Arch. Pharm.-Pharm. Med. Chem. (1996) 329, 475-482.

3. Sharifan, A., Parang, K., Zorrieh-Amirian, H., Nazarinia, M., Shafiee, A. Synthesis of 1-substituted 1,2,4-triazoles, imidazoles and benzimidazoles. J. Heter. Chem. (1994) 31, 1421-1423.

2. Shafiee, A., Parang, K., Khazen, M., Ghasemian, F. Synthesis of substituted 2-(1-methyl-5- nitro-2-imidazolyl)quinolines. J. Heter. Chem. (1992) 29, 1859-1861.

1. Shafiee, A., Pirouzzadeh, B., Ghasemian, F., Parang, K. Synthesis of 2-acetyl-1-methyl -5-nitroimidazole. J. Heter. Chem. (1992) 29, 1021-1023.