Publications

Journal Articles (Last five years)

• Riyaz Basha, Md., Wei, W., Brydie, M, Razmiafshari, M. and Zawia, N.H. (2003). Lead induced developmental perturbations in hippocampal Sp1 DNA-biding are prevented by Zinc. In vivo evidence for Pb and Zinc competition.  Intl. J. Devl. NeuroSci, 21(1): 1-12, 2003.

• Atkins, D.S., Riyaz Basha, Md. and Zawia, N.H. Intracellular signaling pathways involved in mediating the effects of lead on the transcription factor Sp1. Intl. J. Devl. NeuroSci, 21(5): 235-244, 2003.

• Md. Riyaz Basha, Wei, W. and Zawia, N.H. (2003). PCBs and environmental metal Pb exacerbate b-amyloid aggregation and its cytotoxicity in PC12 cells. Ogranohalogen Compounds, 65: 12-15.

• Zawia, N. H., Riyaz Basha, Md., and Razmiafshari, M. An electrophoretic method to determine the ability of xenobiotic metals to bind a specific protein domain. Current Protocols in Toxicology 12. 11: 1-8, 2003.

• Zawia, N.H. Transcriptional involvement in neurotoxicity. Toxicol Appl Pharmacol. 190(2): 177-88, 2003.

• Riyaz Basha, Md., Wei, W., Reddy, G. R. and Zawia, N. H. Zinc finger transcription factors mediate perturbations of brain gene expression ilucidated by heavy metals. In: Molecular Nerotoxicology Environmental Agents and Transcription-Transduction Coupling, (Ed. N. H. Zawia), pp 43-64. CRC press, USA, 2004.

• Basha, M.R., Wei, W., Bakheet^, S.A., Benitez, N., Siddiqi, H.K.,  Ge, Y.W.,  Lahiri, D. K., and Zawia, N.H. The Fetal-basis of Amyloidogenesis: Exposure to Lead (Pb) and Latent Over-expression of APP and β-Amyloid in the Aging Brain.  Journal of Neuroscience, 25: 823-829, 2005.

• Basha, M.R., Murali, M., Siddiqi, K.K., Ghosal, K., Siddiqi, O.K., Lashuel, H.A., Ge, Y.W., Lahiri D.K., and N. H. Zawia (2005). Lead (Pb) exposure and its effect on APP proteolysis and Aβ aggregation, FASEB J. 19(14): 2083-2084, 2005.

• Zawia, N. H. and Basha, M.R. Environmental Risk Factors and the Developmental-Basis for Alzheimer's disease. Rev Neurosci. 16: 325-337, 2005.

• Lahiri, D. K., Ge, Y-W., Maloney, B., Thiel, G., Zawia, N.H., Geig, N.H., Sabamurti, K. (2005). Functional and structural domains of the 5’-flanking regions of the BACE1 gene promoter: implications in Alzheimer’s disease. In (Ed: Fisher, A., Hanin I., Memo, M., and Stocchi, F.) New Trends in Alzheimer and Parkinson Related Disorders: ADPD 2005, pp7-14.

• Donohue, M., Wei, W,, Wu, J., Zawia, N.H., Hud, N., Jesus, V.D., Schmechel, D., Hettick, J.M., Beezhold, D.H., and Vesper. S. Characterization of nigerlysin (c), hemolysin produced by Aspergillus niger, and effect on mouse neuronal cells in vitro. Toxicology. 219(1-3):150-155, 2006.

• Basha, M.R., Brady, N., Zawia, N.H., and Kodavanti, P.R.S. Perinatal exposure to PCBs alters the activity of transcription factors in the brain. Neurotoxicology, 27: 118-124, 2006.

• Bolin, C.S., Basha, M.R., Cox, D., Zawia, N. H., Maloney, B., Lahiri, D. K., and Cardozo-Pelaez, F. (2006). Exposure to lead (Pb) and the developmental origin of oxidative DNA damage in the aging brain.  FASEB J. 20(6); 788-790.

• Lahiri, Debomoy K, Yuan-Wen Ge, Md Basha Riyaz, Bryan Maloney, De-Mao Chen and Nasser Zawia. "Genetics & Epigenetic Studies in AD (Abstract)." Alzheimer's  and Dementia. 2(3,Suppl):S24. July 2006.

• Lashuel, Hilal A. and Nasser Zawia. "Islam: Governments Need to Reform Education and Build a Scientific Culture." Nature. 444(7109):545. November 30, 2006.

• Lahiri, D.K., Maloney, B., Basha, M.R., Ge, Y.W. Zawia, N.H. How and when environmental agents and dietary factors affect the course of Alzheimer’s disease: the “LEARn” model (Latent Early Associated Regulation) may explain the triggering of AD.  Curr. Alzheimer’s Res., 4, 219-228, 2006. 95(2): 436-42.

• Bakheet SA, Basha MR, Cai H, Zawia NH.  Lead exposure: expression and activity levels of Oct-2 in the developing rat brain.  Toxicological Sciences 2007 95(2):436-442.

• Stevens, K.E., Bunch R.W., Anchordoquy, T.J., Zawia, N.H., Zheng, L., Abrams, D.J.  An initial animal proof-of-concept study for central administration of clozapine in schizophrenia patients.  Schizophrenia Bull., 33:479-480, 2007

• Dosunmu R, Wu, J., Basha M.R., and Zawia, N.H. Environmental and Dietary Risk Factors in Alzheimer’s disease: An Overview. Expert Review of Neurotherapeutics.  7, 887-900, 2007.

• White, L.D., Cory-Slechta, D.A., Gilbert, M.E., Tiffany-Castiglioni, E., Zawia,  N.H., Virgolini, M., Rossi-George, A., Lasley, S.M., Qian, Y., Basha, M.R. New concepts in the neurotoxicology of lead (Pb). Toxicol. Applied Pharmacol. 225, 1-27, 2007 .

• Jinfang Wu, Md. Riyaz Basha, Brian Brock, David P. Cox, Fernando Cardozo-Pelaez, Christopher A. McPherson, Jean Harry, Deborah C. Rice, Bryan Maloney, Demao Chen, Debomoy K. Lahiri, and Nasser H. Zawia . Alteration of Alzheimer disease (AD)-like pathology in aged monkeys after infantile exposure to environmental lead (Pb): Evidence for a developmental origin and environmental link for AD. J. Neurosci. 28:3-9, 2008.

• Brock B., Basha, M.R., dePalma, K., Harry, G., Rice, D.C., Zawia, N.H. Immunohistochemical characterization of cerebral APP and Sp1 and its relationship to amyloidogenesis. J. Alzheimer’s Dis. 13:71-80, 2008.

• Daniel J Abrams, MD; Lijun Zheng, MS; Kevin S Choo, MS; Jun J Yang, MS; Wei Wei, MD; Thomas J Anchordoquy, PhD; Nasser H Zawia, PhD; Karen E Stevens, PhD, An Initial Animal Proof-of-Concept Study for Central Administration of Clozapine to Schizophrenia Patients. Schizophr Res. 100:86-96, 2008.

• Joyce E. Royland , Jinfang Wu, Nasser H. Zawia , Prasada Rao S. Kodavanti, Gene expression profiles in the cerebellum and hippocampus following exposure to a neurotoxicant, Aroclor 1254: Developmental effects, Toxicol. Appl. Pharmacol. (2008), doi:10.1016/j.taap.2008.04.022
   

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