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Faculty

Tom Manfredi

Dr. Tom Manfredi

Office: 25 West Independence Way, RM 223

Phone: 401-874-5439

Fax: 401-874-4215

Email: manfredi@uri.edu

Current Position

Professor, Kinesiology

Education & Training

B.S. Physical Education, University of Maryland

M.S. Physical Education & Special Education, University of Maryland

Ph.D., Exercise Science, University of Massachusetts

Teaching/Courses Taught

KIN 334 – Physiology of Exercise

KIN 531 – Physiology of Physical Activity

KIN 562 – Advanced Physiology of Exercise

KIN 564 – Physiology of Aging

Research Interests

Effects of aerobic and strength training on skeletal muscle morphology in older adults

Metabolic related diseases and skeletal muscle mitochondria in older adults

Aging heart and skeletal muscle morphology

Selected Publications

1. Urso, M., Fiatarone Singh, M., Ding, W., Evans, WJ., Cosmas, AC., and Manfredi, TG. Exercise Training Effects on Skeletal Muscle Plasticity and IGF-1 receptors in Frail Elders. AGE 27:117-125, 2005.

2. Urso, Maria, Arthur Cosmas, Maria Fiatarone Singh, Thomas Manfredi. Immunogold Labeling of IGF-1 Receptors in Elderly Human Skeletal Muscle. Scanning. 27:208-212, 2005. FAMS, Inc.

3. Guo, Y., B. Gong, S. Levesque, T. Manfredi, and Y. sun. Automated detection and delineation of mitochondria in electron micrographs of human skeletal muscles. Microscopy Research and Technique. 63:133-139, 2004.

4. Santoro, C., Cosmas, A., Forman, A., Morghan, A., Byros, L, Levesque, S, Hennessey, J, Roubinoff, R, Manfredi, T. Exercise Training Alters Skeletal Muscle Mitochondrial Morphometry in Heart Failure Patients. The Journal of Cardiovascular Risk. 9:1-5,2002

5. Agostinucci, K., T.G. Manfredi, A. Cosmas, K. Martin, S.N. Han, D. Wu, J. Sastre, S.N. Meydani, M. Meydani. Vitamin E and age alter liver mitochondrial morphometry. Journal of Anti-Aging. 5:2; 173-178, 2002.

6. Prakash, P, Manfredi, TG, Jackson, CL, Gerber, LE. B-Carotene alters the morphology of NCL-H69 small cell lung cancer cells. Journal of Nutrition. 132:121-124, 2002.

7. Dean, S.G., Elliott, T.A., Lamont, L.S., Hackney, P.F., Manfredi, T.G., Dean, R.M. Influence of dietary manipulation and exercise on muscle lipids in endurance-trained athletes. International Sports Journal. 4:2, 111-119. Summer, 2000

8. Fielding, R.A., Violan, M.A., Svetkey, L., Abad, L.W., Manfredi, T.G., Cosmas, A.C., Bean, J. Effects of prior exercise on eccentirc exercise-induced neutriphilia and enzyme release. Med. Sci. Sports. Exer. 32:2, 359-364. 2000

9. Fiatarone Singh, M.A., Ding, W., Manfredi, T.G., Solares, G.S., O’Neill, E.F., Celements, K.M., Ryan, N.D., Kehayles, J.P., Fielding, R.A., and Evans, W.J. Insulin-like growth factor I in skeletal muscle after weight-lifting exercise in frail elders. Am. J. Physiology, 277 (Endocrinol. Metab. 40): E135-E143, 1999.

Most Recent External Financial Support

2004 – 2007 - $10,800: 3 awards from the UCONN Foundation (Dr. Arthur Cosmas, Professor at UCONN and Tom Manfredi, URI) for the purchase of a CCD camera, image analysis software, computer, and Millar animal cardiac left ventricular function.

2003 – Support for research study on effects of cadmium on liver mitochondria from URI Biomedical program $2700 s

1995- 2005. – Contract Award “Exercise Science Cooperative Agreement with Slater Hospital” for fall prevention” Contract with Slater Hospital for Fall Prevention Program for Psychogeriatric Patients. Approximately, $52,000/year. Manfredi, T, Annie Connolly and T. Romeo, PI's

2000 – Manfredi, Deville, R. Patterson. Characterization of skeletal muscle in patients with peripheral arterial occlusive disease. The W.L. Gore & Associates, Inc (SP#10021). $2,500

1999 – 2002 – Ying Sun (major P.I.), Robert Hill (P.I.), and TG Manfredi. (P.I.) “Partnership in physiological measurements & computing.” URI President’s partnership grant. $450,000

ANNOUNCEMENTS

New PHETE in Kinesiology
-- How this will effect you
Learn about new Physical Health Education Teacher Education Program (PHETE)
WHEN: Friday 9/18 9am-10am OR Tuesday 9/22 11am-12am. WHERE Kinesiology Conference Room

New for Fall 2009!
The 2009-2010
HSS Living and Learning Community
in Butterfield Hall is a great opportunity for Kinesiology students to network with each other during their first year on campus.

PROGRAM HIGHLIGHTS