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  25 West Independence Way
  Kingston, RI 02881
  Office:401.874.2976
  Fax: 401.874.4215
  Email: dhillman@uri.edu
  

Faculty

Dr. Tom Manfredi Office: 25 West Independence Way,Suite P,RM 223 Phone: 401-874-5439 Fax: 401-874-4215 Email: manfredi@uri.edu

Current Position: 

Professor, Kinesiology

Education & Training

B.S. Physical Education, University of Maryland
M.S. Physical Education & Special Education, University of Maryland
Ph.D., Exercise Science, University of Massachusetts

Teaching/Courses Taught

KIN 334 – Physiology of Exercise
KIN 531 – Physiology of Physical Activity
KIN 562 – Advanced Physiology of Exercise
KIN 564 – Physiology of Aging

Research Interests

Effects of aerobic and strength training on skeletal muscle morphology in older adults
Metabolic related diseases and skeletal muscle mitochondria in older adults
Aging heart and skeletal muscle morphology

Selected Publications

1. Urso, M., Fiatarone Singh, M., Ding, W., Evans, WJ., Cosmas, AC., and Manfredi, TG. Exercise Training Effects on Skeletal Muscle Plasticity and IGF-1 receptors in Frail Elders. AGE 27:117-125, 2005.

2. Urso, Maria, Arthur Cosmas, Maria Fiatarone Singh, Thomas Manfredi. Immunogold Labeling of IGF-1 Receptors in Elderly Human Skeletal Muscle. Scanning. 27:208-212, 2005. FAMS, Inc.

3. Guo, Y., B. Gong, S. Levesque, T. Manfredi, and Y. sun. Automated detection and delineation of mitochondria in electron micrographs of human skeletal muscles. Microscopy Research and Technique. 63:133-139, 2004.

4. Santoro, C., Cosmas, A., Forman, A., Morghan, A., Byros, L, Levesque, S, Hennessey, J, Roubinoff, R, Manfredi, T. Exercise Training Alters Skeletal Muscle Mitochondrial Morphometry in Heart Failure Patients. The Journal of Cardiovascular Risk. 9:1-5,2002

5. Agostinucci, K., T.G. Manfredi, A. Cosmas, K. Martin, S.N. Han, D. Wu, J. Sastre, S.N. Meydani, M. Meydani. Vitamin E and age alter liver mitochondrial morphometry. Journal of Anti-Aging. 5:2; 173-178, 2002.

6. Prakash, P, Manfredi, TG, Jackson, CL, Gerber, LE. B-Carotene alters the morphology of NCL-H69 small cell lung cancer cells. Journal of Nutrition. 132:121-124, 2002.

7. Dean, S.G., Elliott, T.A., Lamont, L.S., Hackney, P.F., Manfredi, T.G., Dean, R.M. Influence of dietary manipulation and exercise on muscle lipids in endurance-trained athletes. International Sports Journal. 4:2, 111-119. Summer, 2000

8. Fielding, R.A., Violan, M.A., Svetkey, L., Abad, L.W., Manfredi, T.G., Cosmas, A.C., Bean, J. Effects of prior exercise on eccentirc exercise-induced neutriphilia and enzyme release. Med. Sci. Sports. Exer. 32:2, 359-364. 2000

9. Fiatarone Singh, M.A., Ding, W., Manfredi, T.G., Solares, G.S., O’Neill, E.F., Celements, K.M., Ryan, N.D., Kehayles, J.P., Fielding, R.A., and Evans, W.J. Insulin-like growth factor I in skeletal muscle after weight-lifting exercise in frail elders. Am. J. Physiology, 277 (Endocrinol. Metab. 40): E135-E143, 1999.

Most Recent External Financial Support

2004 – 2007 - $10,800: 3 awards from the UCONN Foundation (Dr. Arthur Cosmas, Professor at UCONN and Tom Manfredi, URI) for the purchase of a CCD camera, image analysis software, computer, and Millar animal cardiac left ventricular function.

2003 – Support for research study on effects of cadmium on liver mitochondria from URI Biomedical program $2700 s

1995- 2005. – Contract Award “Exercise Science Cooperative Agreement with Slater Hospital” for fall prevention” Contract with Slater Hospital for Fall Prevention Program for Psychogeriatric Patients. Approximately, $52,000/year. Manfredi, T, Annie Connolly and T. Romeo, PI's

2000 – Manfredi, Deville, R. Patterson. Characterization of skeletal muscle in patients with peripheral arterial occlusive disease. The W.L. Gore & Associates, Inc (SP#10021). $2,500

1999 – 2002 – Ying Sun (major P.I.), Robert Hill (P.I.), and TG Manfredi. (P.I.) “Partnership in physiological measurements & computing.” URI President’s partnership grant. $450,000

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